Functional/Anti-Aging Medicine

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Discusses diet, exercise, nutritional supplementation, bioidentical hormones, and neurotransmitters for healthy aging.

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Anti-Aging/Functional MedicineRandy A. Birken, MD Clinical Assistant ProfessorBaylor College of MedicineBirken Medical Aesthetics281-419-3231 : 

Anti-Aging/Functional MedicineRandy A. Birken, MD Clinical Assistant ProfessorBaylor College of MedicineBirken Medical Aesthetics281-419-3231

Anti-Aging/Functional Medicine : 

Anti-Aging/Functional Medicine http://tinyurl.com/qytm8z

Aging : 

Aging I don't want to achieve immortality through my work. I want to achieve it through not dying. I'm not afraid to die, I just don't want to be there when it happens. Woody Allen

Anti-Aging/Functional Medicine : 

Anti-Aging/Functional Medicine Poor diet, inadequate supplementation, imbalanced hormones and neurotransmitters as well as exposure to environmental toxins may predispose an individual to illness and specific symptoms.

What are the Effects of Aging? : 

What are the Effects of Aging? Decrease Immune Function Decrease in Muscle Mass Decrease in Bone Mass Decrease in Cellular Protein Synthesis Increase in risks for Diseases

Goal of Anti-Aging Medicine : 

Goal of Anti-Aging Medicine Increase healthspan not just lifespan Aging cannot be reversed, but healthy aging with good physical, physiological, and emotional well-being is obtainable

Anti-Aging Basics : 

Anti-Aging Basics Diet Exercise (physical and mental) Vitamins, Anti-oxidants, Minerals, Nutritional Supplementation Bio-identical Hormones Neurotransmitters

Diet : 

Diet Mediterranean Diet: A notably low incidence of chronic diseases and high life expectancy rates is present in populations living along the Mediterranean Sea (particularly Greeks and southern Italians): Grains, fruits, vegetables, legumes (peas, beans, lentils, nuts), good fats - olive oil and omega-3 fatty acids (fish), occasional red meat Okinawan Diet: Elderly Okinawans have among the lowest mortality rates in the world from a multitude of chronic diseases of aging and as a result enjoy not only what may be the world's longest life expectancy, but the world's longest health expectancy: Low caloric intake, high vegetables/fruit consumption, higher intake of good fats – omega 3 and monounsaturated fat, high fiber, high flavonoid intake (citrus, gingko, tea, wine, chocolate)

Exercise : 

Exercise Reduces the risk of heart disease Maintains healthy weight, cholesterol, blood pressure Prevents bone loss Reduces stress, tension, anxiety, depression Increases muscle strength and energy

Alcohol : 

Alcohol Drinking one or two alcoholic drinks each day could help reduce the risk of developing dementia. [The Lancet 2002; 359:281-286] Light to moderate drinking appears to protect the elderly from developing small blockages in the blood vessels of the brain known as silent strokes therefore lowering stroke risk. [Stroke 2001 32: 1939-1946]

Sleep : 

Sleep Sleep is … Necessary for survival. Necessary for proper nervous system function Rejuvenates brain nerve cells and promotes brain function

Water : 

Water Replenish lost fluids with an intake of eight to twelve ounces of water every day 53 million Americans drink water from municipal water supplies containing potentially dangerous levels of chloro- and fluoro-chemicals, lead, fecal bacteria as well as pesticides and other impurities associated with cancer and metabolic dysfunction

Free Radicals and Oxidative StressAll cells & tissues are constantly subjected to highly sensitive molecules called free radicals. This is termed oxidative stress.These hostile, damaging molecules are normal byproducts of life’s metabolism of food substances or oxidative metabolism.Free radicals are also produced by smoke, radiation, air pollution, chemicals, toxic metals, oxidized fats. : 

Free Radicals and Oxidative StressAll cells & tissues are constantly subjected to highly sensitive molecules called free radicals. This is termed oxidative stress.These hostile, damaging molecules are normal byproducts of life’s metabolism of food substances or oxidative metabolism.Free radicals are also produced by smoke, radiation, air pollution, chemicals, toxic metals, oxidized fats.

Nutraceuticals : 

Nutraceuticals There is strong scientific evidence from large and respected clinical trials that have confirmed the safety and efficacy of nutraceuticals.

Nutraceuticals : 

Nutraceuticals Essential Nutrients: Beta carotene Vitamin C & Vitamin E Selenium Zinc Cysteine Endogenous Compounds: Glutathione Sulfhydryl groups Lipoic Acid CoQ10

Nutraceuticals : 

Nutraceuticals Dietary Compounds: Bioflavinoids (Citrus, tea, gingko, onions, parsley, dark chocolate) Proanthocyanidins (apples, red wine, black and green tea, etc.) Antioxidants recharge each other and are synergistic or additive.

Anti-Oxidants : 

Anti-Oxidants Glutathione Cysteine CoQ10 Selenium Vitamin E Alpha Lipoic Acid Vitamin C

Minerals : 

Minerals Chromium and Vanadium facilitates action of insulin and maintains normal blood sugar Zinc: cofactor in many enzymes Beneficial for prostate health Decreased cancer risk 30-100 mg / day

Probiotics : 

Probiotics Lactobacillus, Acidophilus and Bifidobacterium bifidum. Maintains normal intestinal flora and function Used in intestinal dysbiosis, diarrhea, irritable colon, ulcerative colitis Use along with antibiotics to prevent change in intestinal flora

Micronutrient Testing : 

Micronutrient Testing SpectraCell (Houston, TX) www.spectracell.com Measures the biochemical function of vitamins, minerals, amino acids and antioxidants via blood test Functional intracellular testing with targeted nutrient repletion recommendations for vitamins and minerals found to be deficient Very advanced and sophisticated technique

Micronutrient Testing : 

Micronutrient Testing Genova Diagnostic (Asheville, NC) www.gdx.net A comprehensive nutritional evaluation to identify specific imbalances of vitamins, nutrients, and essential co-factors. This profile also provides assessment of gastrointestinal dysfunction and detoxification impairment via urine testing

Dr. Birken’s Protocol : 

Dr. Birken’s Protocol Multiple Vitamins Vitamins A, C, D3, E, K, Thiamine, Riboflavin, Niacin, B6, Folate, B12, Biotin, Pantothenic Acid, Calcium, Iodine, Magnesium, Zinc, Selenium, Copper, Manganese, Chromium, Molybdenum, Boron, Vanadium, Choline, Inositol, Bioflavanoids,

Dr. Birken’s Protocol : 

Dr. Birken’s Protocol Niacin-SR 500mg sustained release – one per day Omega 3 Fish Oil Marine Fish Concentrate, Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA) 1000mg twice per day

Dr. Birken’s Protocol : 

Dr. Birken’s Protocol Probiotic 3.0 billion viable microorganisms as Lactobacillus acidophilus, Lactobacillus rhamnosus, and Bifidobacterium longum – twice per day Whey Protein Powder Magnesium, Sodium, Potassium, L-Alanine, L-Arginine, L-Aspartic Acid, L-Cysteine, L-Glutamic Acid, Glycine, L-Histidine, L-Isoleucine, L-Leucine, L-Lysine, L-Methionine, L-Phenylalanine, L-Proline, L-Serine, L-Threonine, L-Threonine, L-Tyrosine, L-Valine, L-Carnitine (as L-carnitine tartrate) – one scoop per day

Hormones : 

Hormones Estrogen Progesterone (not synthetic progestin) Testosterone Thyroid DHEA

Women’s Health Initiative Study : 

Women’s Health Initiative Study The WHI trials should not be regarded as truth and all other research discarded (NAMS) A recent study from Australia showed estrogen’s protective effect against dementia and Alzheimer disease Four recent studies and meta-analyses show a protective effect of HRT on cognition, dementia, CAD

Hormones : 

Hormones Estrogen protects against heart disease, stroke, osteoporosis, Alzheimer’s, and memory disorders as well a decreasing fatigue, depression, mood changes, enhancing libido, reducing wrinkles, colon cancer, and dental cavities Progesterone protects against breast cancer, osteoporosis; it has natural anti-anxiety and helps sleep

Hormones : 

Hormones Testosterone increase muscle mass, strength, endurance, well being, and mood stability, and libido. Protects against cardiovascular disease and arthritis as well as improving skin texture and tone Thyroid increases fat breakdown, aids in weight reduction, lowers cholesterol, as well as decreasing heart disease and cognitive impairment

Hormones : 

Hormones DHEA increases metabolism, reduces cardiovascular disease by increasing fat breakdown, improves libido, mood, and immunity HGH, while controversial, does stimulate tissue repair, healing, cell rejuvenation, bone strength, metabolism, cardiovascular health, brain function, and energy. Could prove to be the best anti-aging hormone.

Hormones : 

Hormones Bio-identical hormones are biological identical to human molecules – safe, effective, and the cornerstone to age management. BHRT are not drugs! Synthetic hormones are different and potentially dangerous

Neurotransmitters : 

Neurotransmitters Chemicals that serve as messengers between the brain and organs Analogous to the body’s internal telephone system Must have adequate levels to be healthy

Neurotransmitters : 

Neurotransmitters Imbalanced neurotransmitter levels lead to many clinical conditions including: Fatigue Weight problems Anxiety Depression Insomnia

Neurotransmitters : 

Neurotransmitters Excitatory neurotransmitters: Energizing Motivating Focus Rev up the system Glutamate, Epinephrine, Norepinephrine, PEA, Histamine, Aspartic Acid, Dopamine

Neurotransmitters : 

Neurotransmitters Inhibitory neurotransmitters: Calming Relaxing Sleep inducing Slow down the system GABA, Serotonin, Glycine, Taurine, Agmatine

Neurotransmitters : 

Neurotransmitters Neurotransmitter levels are affected by: High levels of stress Poor diet Environmental toxins Genetic predisposition

Neurotransmitters : 

Neurotransmitters Neurotransmitter imbalances can be detected through a non-invasive urinary and saliva testing and can be corrected through natural amino acid supplements.

Functional Medicine/Age Management Summary : 

Functional Medicine/Age Management Summary Optimal health and longevity requires proper diet, exercise, nutritional supplementation, bio-identical hormone replacement, and optimal neurotransmitters Physical deterioration is not a requirement of growing older!

Anti-Aging/Functional Medicine : 

Anti-Aging/Functional Medicine It is now possible to stop much of the undesirable symptoms of aging as well as diseases associated with aging

Anti-Aging/Functional Medicine : 

Anti-Aging/Functional Medicine Randy A. Birken, MD Clinical Assistant ProfessorBaylor College of MedicineBirken Medical Aesthetics www.birkenmedicalaesthetics.com [email protected] 281-419-3231