02. Bovine Papillomatosis

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CANINE PARVO INFECTION:

CANINE PARVO INFECTION BY- ANUP GOYAL ROLL NO. 01 REG. NO. 02-00122-06

INTRODUCTION:

INTRODUCTION Canine parvo virus was recognised in 1978 in USA and in 1981 in INDIA. Canine parvo virus belongs to family PARVOVIRIDAE It is a smallest DNA virus. It has single standard DNA and has Icosahedral symmetry.

CONT…:

CONT… This virus has got close antigenic relationship with the PANLEUKOPENIA VIRUS Parvo virus has got two strains – CPV- 1 CPV- 2 CPV- Canine parvo virus

HOST :

HOST Parvo virus affect cattle , pig , dog ,cat , man , rat , mice mink and hamster. Breeds like DOBERMANN and LABRADOR are at higher risk.

PATHOGENISIS:

PATHOGENISIS Virus affect cells which are undergoing mitosis, so young dogs are specially attacked . Virus has got affinity for the lymphocytes and the lymphatic system and thus has immunosuppresive effect. Virus is found in the intestinal epithelium and the cardiac muscle.

CLINICAL FINDINGS:

CLINICAL FINDINGS Two conditions are observed- 1-Parvo virus entritis 2-Parvo virus myocarditis

PARVO VIRUS ENTRITIS:

PARVO VIRUS ENTRITIS Symptoms are- Haemorrhagic gastroentritis Slight to high rise of temperature at initial stage but gradually turn to subnormal level. Vomition and Diarrhoea . Brownish semi – solid faeces Retching and restlessness.

PARVO VIRUS MYOCARDITIS:

PARVO VIRUS MYOCARDITIS Symptoms are – Pups under 10 weeks of age usually suffer. Heart muscle damaged . Respiratiry problem. Circulatory failure. Pulmonary odema.

DIAGNOSIS:

DIAGNOSIS Animal Innoculation test . Serum Neutralization test . Isolation of the virus . Haemagglutination test . Haemagglutination inhibition test . Fluorescense antibody test. ELISA

Cont…:

Cont… Haematology – Leukopenia due to lymphopenia and granulocytopenia develop. AGPT – done by using suspected faecal sample with known antibody .

TERATMENT:

TERATMENT No specific treatment . Only symptomatic treatment is given . Fluids and electrolyte is given . Broad spectrum antibiotic is given. Vomition is prevented by METACLOPROMIDE Diarrhoea is prevented by LOPRAMIDE .

VACCNIES:

VACCNIES PARVOCINE – Parvo dog vaccine prepared by M/s serum institute of India limited. This is canine origin parvo virus strain modified by 115 successive passage on cell culture and freeze dried. CANDUR – P . PENTADORE .

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