Health monitering by microchips embedded in drugs


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Here is a solution for alzheimer's disease.......


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HEALTH MONITERING USING MICROCHIPS EMBEDDED IN TABLETS 3rd congress on Research Awareness and science career opportunities in India and abroad 6th of February 2014 :

HEALTH MONITERING USING MICROCHIPS EMBEDDED IN TABLETS 3 rd congress on Research Awareness and science career opportunities in India and abroad 6 th of February 2014 ARUNAI ENGINEERING COLLEGE, Department of Biotechnology , 2 nd YEAR, ( Chandan.K , Ramanan.A.T )


INTRODUCTION Here the microchips provids secure, reliable, real-time information to patients. The concept of biomedical telemetry from ingestible electronics was proposed in the year 1960s in a series of lectures aimed at educating biologists, physicians, and engineers about the use of radio to sense and transmit biological signals from animals and humans. .


AIM & OBJECTIVE Integrate adherence data, physiologic metrics and consumer input. Allow patients to access and share data with physicians, family members and/or caregivers. Provides a plateform for targeting feedback and providing tailored management for wellness promotion.


COMPONENTS USED 1. Edible sensor embedded in a drug product. 2. Health monitor.


D E SCRIPTION & WORKING (i) Edible Sensor:  (Proteus Digital Health)

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Edible sensor consists of an IC ( integrated circuit ) in the centre, surrounded by a frible disc. The IC is Coated with copper and magnesium salt The Fibric disc is 5.0mm in diameter and 200 µ thickness. The Over all weight is approximately 5mg Battery i anode ( magnesium ) ii cathode ( copper salt ) iii electrolyte (HCL acid presenty in stomach) Redox reaction voltage of1-2 V is produced and stored in capacitor. The edible sensor are designed to communicate for a finite period of time approximately 7minutes. Soluble copper salts and magnesium are released to body and bulk of edible sensor is eliminated form body through excreation process.

Wearable Health Monitor :

Wearable Health Monitor Placement of wearable health monitor on the body. First generation of clinical Version of a wearable Health monitor 155 x 93 x 27 mm and 300 grams. S econd generation clinical version is in triangular shape,88 mm per side and 8 mm height which is adhesive electrode base. (Proteus Digital Health)


Several clinical versions have been developed, ranging from a large device worn via a belt clip to an on-body device that can be adhered to a pateints body. Adhered to the patients body using an adhesive electrode base comprised of three biocompatible, electrocardiogram ( ECG ) -style Ag-AgCl electrodes. Electrode allows the monitor to sample the patients biopotentials where the electrodes are attached. Monitor assess the impedance across each electrolyte pair by applying alow-amplitude, alternating current and measuring the resulting voltage. In this case the health monitor has a printed circuit board and a rechargeable battery powering the monitor for approximately 7 days. Consist of five main blocks i data logging engine ii signal chain for high frequency sensor data iii signal chain for low frequency sensor data iv communication subsystem v accelometer

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( Lorenzo DiCarlo  (  [email protected] ), Greg Moon, Allison Intondi, Robert Duck, Jeremy Frank, Hooman Hafazi, Yashar Behzadi, Timothy Robertson, Ben Costello, George Savage, and Mark Zdeblick are with Proteus Digital Health Incorporated, Redwood City, California )


CLINICAL STUDY IN HUMAN There was no unanticipated d evice adverse effect. The most commonly observed is mild skin rash associated with the commercial electrodes placed on a subjests body.


CONCLUSION “H ealth monitering using microchips embedded in tablets” paves a excellent way for the drug delivery to the patients without any faliure. It provides secure, reliable, real-time information to patients. Provides improved outcomes and reduced healthcare expenditure by keeping patient on their medications.


OUTLOOK Alzheimer's disease is the major problem in many countries and there is no cure for this disease. In this case consumption of drug by the patient should be monitored in regular interval of time. There the “Health monitering using microchips embedded in tablets” come into picture and we can apply this idea for this disease.


ACKNOWLEDGMENT Kit Yee Au- Yeung , PhD, Timothy Robertson, PhD, Hooman Hafezi , PhD, Gregory Moon, MD, Lorenzo DiCarlo , MD, Mark Zdeblick , PhD, George Savage, MD . Proteus Biomedical, Inc. 2600 Bridge Parkway, Suite 101 Redwood City, CA 94065, USA 1 (650) 632-4031

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