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Analytical Method development by Liquid Chromatography
Analytical methods development and validation play important roles in the discovery, development, and manufacture of pharmaceuticals. The current good manufacturing practice (cGMP) and Food Drug Administration (FDA) Guidelines insist for adoption of sound methods of analysis with greater sensitivity and reproducibility. This thesis describes analytical methods developed for drug determination in pharmaceutical dosage forms and biological matrixes including Chromatography (RP-HPLC) and Hyphenated Techniques (LC-MS/MS). Methods have been developed for separation and quantification of selected drugs from categories like Antihypertensive, Antihyperlipidemic, Skeletal Muscle Relaxant, Non-Steroidal Anti-inflammatory Drug (NSAID), Antibiotic, Anticonvulsant, Antiviral, and Analeptic.
Tags:
Analytical , Chromatography , Development , Liquid , Method
By:
kunasahu1
Entertainment
113 months ago
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Drug Interactions of Fibrates
· Contraindicated Combinations of Fibrates include Fibrates & Ciprofibrate, Gemfibrozil & Repaglinide, Gemfibrozil & Dasabuvir and Gemfibrozil & Simvastatin.· Major Interactions of Fibrates include Fibrates & Ezetimibe, Fibrates & Sulfonylurea Antidiabetics (Glyburide, Glipizide, Glimepiride, etc), Gemfibrozil & Other Statins (Lovastatin, Atorvastatin, Fluvastatin, Pravastatin), Gemfibrozil & Colchicine, Fenofibrate & Anticoagulants, Bezafibrate & Bile acid Sequestrants (Cholestyramine, Colestipol, Colesevelam).
Tags:
Antihyperlipidemics , Clofibrate , Drug Interactions of Fibrates , Fenofibrate , Gemfibrozil
By:
nainamohamedpakk
Education
57 months ago
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