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BY VENKATA NAVEEN KASAGANA & SWATHI SREE KARUMURI {M-PHARM -PHARMACEUTICS} S.B. COLLEGE OF PHARMACY SIVAKASI TAMIL NADU INDIA E- MAIL:naveen.kasagana@gmail.com
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CONCEPTS OF OPTIMIZATION
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FLOW DIAGRAM OF ZENECA TABLET FORMULATION
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PRODUCT OPTIMISATION PURPOSE AND SCOPE The major objective of the product optimisation stage is to ensure that the product selected for further development (the intended commercial product) is fully optimised and complies with the design specification and critical quality parameters described in the Product Design Report. The key outputs from this stage of development will be: • a quantitative formula defining the grades and quantities of each excipient and the quantity of candidate drug; • defined pack; • defined drug, excipient and component specifications; and • defined product specifications.
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OTHER OPTIMIZATION METHODS
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REFERENCE MODERN PHARMACEUTICS BY Gillbert , S . B anker OPTIMIZATION TECHNIQUES BY Joseph B. Schwartz, Robert e. O'Connor, roger l. Schnaare 2. PHARMACEUTICAL PREFORMULATION AND FORMULATION BY Mark Gibson.
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THANK YOU