“The Transfer Factors” as Immunomodulators :“The Transfer Factors” as Immunomodulators


What are transfer factors ? :What are transfer factors ? Discovered in 1949 by Dr. H. Lawrence Peptides ( 44 amino acids) Mol wt < 10,000 Daltons Immunomodulators Immune messenger which transfer signals between immune cells… warn the body cells of the potential danger They help us to be more healthy … keep our immune system more intact


Transfer factors are Immunomodulators :Transfer factors are Immunomodulators Maintain healthy immune system Set a strong immune response … Three R’s of Immunity Recognize (a disease causing organism) React (organise and mount an attack to eradicate that organism) Remember (the organism that caused the disease, so that the next time it invades, an immediate reaction occurs)


Slide 4:We all get sick sometimes...but then we get better. What happens when we get sick? Why do we get better?


What makes us get better is our Immunity… :What makes us get better is our Immunity… Immunity The ability of the body to fight infection and/or foreign invaders by producing antibodies or killing infected cells.


First Line of Defense – The Skin :First Line of Defense – The Skin Provides Physical and Chemical barriers Physical – hard to penetrate, made of indigestible keratin Chemical – tears, sweat


Second Line of Defense – Nonspecific Immune Response :Second Line of Defense – Nonspecific Immune Response These defenses include: Phagocytosis – done by Macrophages Natural Killer Cells Inflammation - caused by release of Histamine from leukocytes Fever – caused by histamines. Macrophage and E. coli


Third Line of Defense – Specific Immune Response :Third Line of Defense – Specific Immune Response The response involves the creation of Antibodies.


The initial ammunition is provided by the mother – Passive immunity :The initial ammunition is provided by the mother – Passive immunity While our immune system is developing, we are protected by immune defenses called antibodies. These antibodies travel across the placenta from the maternal blood to the fetal blood. Antibodies are also found in breast milk. The antibodies ( Y) received through passive immunity last only several weeks.


Where do the transfer factors come from ? :Where do the transfer factors come from ? In humans, the transfer factors from mother's more experienced immune system pass to her baby via Colostrum “The first milk that offspring receives immediately after birth” The Colostrum is packed with army of immune components


A brief history of transfer factor… :A brief history of transfer factor… Discovered in 1949, while studying Tuberculosis 1989 – transfer factors were extracted from cow’s Colostrum Patented on USA 1999 – efficacy and safety established globally in various clinical studies Dr. Gary Wilson and Dr. Greg Paddock got the US FDA approval for the extraction technology to the final capsule available for human consumption


Is the transfer factor supplementation superior to cows Colostrum ? :Is the transfer factor supplementation superior to cows Colostrum ? Cow Colostrum can cause allergic reaction in few individuals … NO RISK with TF Supplements Cow Colostrum contains some random transfer factors only , hence a person would have to take an enormous amount of Colostrum to see significant efficacy… 200 factors have been isolated on TF supplements


Clinical implications of Transfer Factors… :Clinical implications of Transfer Factors… Immunomodulation means… Activate immune response during attack by bacteria, virus, fungus or parasite infections in susceptible individuals Normalize & balance an overall aggressive immune system as seen in rheumatoid arthritis, multiple sclerosis


Indications for use of Transfer factor :Indications for use of Transfer factor Underactive Immune disorders Infections ( Viral, Bacterial, Fungal, Parasitic) Cold and Flu Hepatitis Tuberculosis Cancer HIV 1


Indications for use of Transfer factor :Indications for use of Transfer factor Overactive Immune disorders Allergies Asthma Rhinitis Urticaria Eczema 2


Indications for use of Transfer factor :Indications for use of Transfer factor Autoimmune disorders Psoriasis Rheumatoid arthritis Multiple sclerosis Lupus Scleroderma 3


Indications for use of Transfer factor :Indications for use of Transfer factor Inflammatory disorders IBS Fibromyalgia Crohn’s disease Ulcerative colitis Celiac disease 4


Expert opinion on use of Transfer factors Extract :I'm a cancer physician. I primarily treat female cancer and certainly encourage my patients who are undergoing chemotherapy and radiation therapy to take transfer factor. It helps to modulate the immune system and is great for overall health. I have patients with chronic herpes infections who are taking transfer factor on a regular basis. These patients have reported a reduction in the no. of outbreaks. I've also had patients with chronic yeast infections consuming transfer factor and are reporting improvement as well. Dr. Townsend Expert opinion on use of Transfer factors Extract


Slide 20:Dr. Markowitz I have now completed a retrospective study comparing children in our practice with those who did not use transfer factor during the same period. Eighty-seven children, used transfer factor. We found 74% less reported illness and 84% less reported use of antibiotics Expert opinion on use of Transfer factors Extract


Expert opinion on use of Transfer factors Extract :Expert opinion on use of Transfer factors Extract A while ago I came down with a cold and flu. I got a runny nose and a sore throat, and then I had an opportunity to use this transfer factor. I decided I would take nothing else. In a 24-hour time period I felt great! I had no symptoms. It was like I'd never had a cold. It was very exciting for me to experience that firsthand. It's just remarkable Dr. Gary Haagen


How do the transfer factor extract act ? :How do the transfer factor extract act ? Influence activity of macrophages and T – lymphocytes (Help body to Recognize the antigen) Enhance activity of macrophages - e.g. Phagocytosis Stimulate the activity of NK cells ( by 103%)


Evidence :Evidence Global publications of 3000 Scientific papers 11 International conferences on Transfer factors Clinical evidences in various conditions like Viral hepatitis, Chlamydia infections, Duodenal ulcers, Cancer, Acute osteomyelitis, Atopic dermatitis, HIV infection etc, with proven significant improvement.


Extract of Transfer factors available as … :Extract of Transfer factors available as … Transfer Factor XF Derived from Bovine Colustrum Contains Transfer factor powder ( extract ) + Maltodextrin Available as a gelatin capsule


Slide 25:Transfer Factor Plus Derived from Bovine Colostrum Contains Transfer factor powder ( extract ) + Zinc monomethionine 20% (3.3 mg zinc) + Proprietary Cordyvants mixture + Inositol Hexaphosphate + Soya bean extract + Cordyceps sinensis powder + Bakers yeast ( D-b-glucan) extract + Lemon peel powder + Aloe gel powder ( Aloe Vera leaf) + Oats extract Avena Sativa ( b-glucan) + Olive tree ( Olea europaea) leaf powder extract + Maitake Mushroom (Grifolea frondosa) powder extract + Shiitake Mushroom ( Lentinus edodes) powder extract Extract of Transfer factors available as …


How should we use the extract of transfer factors ? :How should we use the extract of transfer factors ? For prevention 1 capsule 3 times daily for 30 days For acute infections, at the beginning of disease 2 capsules 3 times daily for not less than 7 days


Summary :Summary Immunomodulation is a successful therapeutic option Immunomodulation effects of transfer factors are useful in treating infections, somatic pathologies associated with disturbance of immune status Clinical experience and evidence support the use of these products and the potential to use these products is huge.