pillcam_NPD

Slide 1: 

Presented by- Shakil S.Siddiqui Rizvi Institute of Management studies & Research. Mumbai.

Slide 2: 

PILLCAM A pill with a view

PILLCAM : 

PILLCAM A product by GIVEN IMAGING Approved by European Medicines Agency Capsule Endoscopy 3 types Pillcam ESO Pillcam SB Pillcam colon

New product development of the Pillcam: 

New product development of the Pillcam IDEA GENERATION PRODUCT SELECTION PRELIMINARY PRODUCT DESIGN FINAL PRODUCT DESIGN PROTOTYPING THE DESIGN TESTING OF PROTOTYPE 6 S T E P S

1.IDEA GENERATION Normal traditional endoscopy: 

1.IDEA GENERATION Normal traditional endoscopy

Problems with normal endoscopy: 

Problems with normal endoscopy Sore throat Greater recovery time Requires sedation Painful Time consuming accidental puncture fever

Imagine a vitamin size pill sized camera that could travel through our body taking pictures, helping to diagnose a problem: 

Imagine a vitamin size pill sized camera that could travel through our body taking pictures, helping to diagnose a problem

2.Product selection: 

2.Product selection Endoscopy with - Clear images Simple and safe No need of inducing sedation Detect evidence of disease that traditional endoscopy cannot No pain Small recovery time

3.Preliminary product design: 

3.Preliminary product design Basic components for required for designing a product were Lens Illuminating LED Image sensor Battery Transmitter

Preliminary product design: 

Preliminary product design

PARTS OF THE PRODUCT : 

PARTS OF THE PRODUCT 1.Optical dome 2.Lens holder 3.Lens 4.Illuminating LED”s 5.CMOS image sensor 6.Battery 7.ASIC transmitter 8.Antennae

1.Optical dome: 

1.Optical dome Have Light receiving window Made up of non conductor material Promote easy orientation Prevent infiltration of digestive fluids inside the capsule Easy propelling

2.Lens holder: 

2.Lens holder Helps to accommodate the lens Helps the lens to fix properly Avoids dislocation of lens

3.Lens : 

3.Lens Integral component Location – behind light receiving window Light through window falls on the lens

4.Illuminating LED”s: 

4.Illuminating LED”s Six white light emitting diode (LED) ensure proper lighting for taking pictures.

5.CMOS image sensor: 

5.CMOS image sensor 140° field of view Detects object as small as 0.1 mm Precise Detect a polyp which is not possible in traditional endoscopy

6.Battery: 

6.Battery 2 battery Button shaped Made up of silver oxide Disposable Harmless 8 hrs. working

7.ASIC transmitter: 

7.ASIC transmitter Application specific integrated circuit Location – behind the batteries 2 transmitting electrodes are present Electrodes are electrically isolated

8.Antennae: 

8.Antennae Receives data from ASIC transmitter Send to data recorder

4.PROTOTYPING THE DESIGN : 

4.PROTOTYPING THE DESIGN

Slide 21: 

PROBLEMS WITH THE PROTOTYPE AND THEIR SOLUTIONS Patients with narrow gastrointestinal structures are not good candidates for this procedure due to risk of obstruction Solution -Use of nanotechnology pill size has been reduced like normal vitamin capsule Impossible to control camera behavior in colon (rotation of pill can be possible) Solution-Use of bi-directional telemetry camera

5.TESTING OF PROTOTYPE: 

5.TESTING OF PROTOTYPE Clinical trials Sampling method : Non-probability sampling Ages eligible for study: 18 Years to 70 Years Genders Eligible for Study: Both Tested on both healthy volunteers as well as on ill patients

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ill patients includes- mechanically ventilated and sedated mild-to-moderate brain injury patients admitted to an intensive care unit (ICU) Patients having GERD (gastro esophageal reflux disease) Cancer patients

RESULTS: 

RESULTS large studies with consistent clinical data continue to support the use of Pillcam capsule endoscopy as a first-line diagnostic tool for patients who suffer from unresolved G.I.T symptoms It is completely safe

6.FINAL PRODUCT DESIGN: 

6.FINAL PRODUCT DESIGN

Slide 26: 

Pillcam SB take 50,000 images in 8 hr. i.e., 2 image/sec Pillcam Eso . Take 2,600 images in 20 min i.e., 14 images/sec

SENSOR ARRAY BELT: 

SENSOR ARRAY BELT This sensor array belt has to worn around patients waist over clothing it has data recorder in it which has battery which receives pictures from the antennae of the Pillcam and record it which is later displayed on the monitor

PROCEDURE: 

PROCEDURE Fasting for 10-12 hours No iron pills for 5 days Swallow the capsule with few sips of water Capsule moves by peristalsis movement Patient can leave the center After 7-8 hours the patient must return Collect images from data recorder and examine it

ADVANTAGES OF PILLCAM: 

ADVANTAGES OF PILLCAM Painless No side effects Accurate pictures(view of 150 degree) High quality images Easy procedure High sensitivity and specificity No sedation is required More efficient than X-ray ,CT-Scan and normal endoscopy

LIMITATIONS: 

LIMITATIONS Very expensive Gastrointestinal obstruction prevent the free flow of Pillcam Pregnant woman and patients with pacemaker face difficulties Not a replacement for colonoscopy Not reusable Batteries may not last long

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THANK YOU