logging in or signing up Types of Mutations science208 Download Post to : URL : Related Presentations : Let's Connect Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Copy embed code: Embed: Flash iPad Dynamic Copy Does not support media & animations Automatically changes to Flash or non-Flash embed WordPress Embed Customize Embed URL: Copy Thumbnail: Copy The presentation is successfully added In Your Favorites. Views: 16788 Category: Education License: All Rights Reserved Like it (21) Dislike it (2) Added: June 25, 2008 This Presentation is Public Favorites: 8 Presentation Description Presenation that describes the different types of mutations. Comments Posting comment... By: rashaalali1 (11 month(s) ago) Can I please use this in my class, could you plz send me a copy firstname.lastname@example.org Saving..... Post Reply Close Saving..... Edit Comment Close By: xmarlo (29 month(s) ago) nice Saving..... Post Reply Close Saving..... Edit Comment Close By: mhjaved (32 month(s) ago) It is excellent presentation. I will appreciate if you send me this presentation for my student class. I am Professor of Physiology and will teach Cancer and Genetics topics to our medical students in September, 2011. My official address if Dr Masood-ul-Hassan Javed, PhD Professor of Physiology Sulaiman Al Rajhi University Medical College PO Box 777, Bukaryiah 51941, KSA Tel: 0096663355555/124; Mobile: 0592739044 Email: email@example.com www.sr.edu.sa Best regards. Saving..... Post Reply Close Saving..... Edit Comment Close By: kavithamahesh (34 month(s) ago) Can u please sene me a copy of the ppt at firstname.lastname@example.org Saving..... Post Reply Close Saving..... Edit Comment Close By: joyg (35 month(s) ago) very good Saving..... Post Reply Close Saving..... Edit Comment Close loading.... See all Premium member Presentation Transcript Slide 1: MUTATIONS Slide 2: A change in the genetic material of a cell. Good Bad Neutral Mutation : Germ cell mutations Somatic mutations occur in the organisms body cells occur in organisms germ cells 2 types: Chromosome Mutations either changes in the structure of a chromosome or the loss of an entire chromosome. : Chromosome Mutations either changes in the structure of a chromosome or the loss of an entire chromosome. Where can mutations occur? Gene Mutations involve large segments of DNA or a single nucleotide within a codon. Slide 5: Point mutation - substitution Frameshift mutation - insertions - deletions Gene Mutations THECATSAWTHEDOG : THECATSAWTHEDOG THE CAT SAW THE DOG Word = Codon Sentence = Gene Letter = Nucelotide base Substitution of one letter : Substitution of one letter THE BAT SAW THE DOG THE CAT SAW THE DOG 2. THE CAT SAW THE HOG 3. THE CAT SAT THE DOG ↑ ↑ ↑ Slide 8: - when a single nucleotide is replaced with a different nucleotide Base substitution Point Mutation Sickle Cell Anemia : Sickle Cell Anemia DNA mRNA Amino acid C G T A Glutamic acid T A C G A U Valine T A Normal Substitution Deletion- one nucleotide in a codon is deleted : Deletion- one nucleotide in a codon is deleted THE CAT SAW THE DOG THE ATS AWT HED OG Loss of one letter Loss of C Insertion one nucleotide in a codon is added : Insertion one nucleotide in a codon is added THE CAT SAW THE DOG THE CMA TSA WTH EDO G Gain of one letter Insertion of M ↑ Slide 12: THE CAT SAW THE DOG THE ATS AWT HED OG THE CMA TSA WTH EDO G - Caused by the insertions or deletions of a nucleotide - Alters the triplet grouping of nucleotides into codons - Shifts the reading frame so that all nucleotides downstream will be improperly grouped. Frameshift mutations Chromosome Mutations : Chromosome Mutations Deletions Inversions Translocations Nondisjunction Deletion : Deletion Loss of piece of a chromosome due to chromosomal breakage Lethal mutation- cause death of the organism D E F G Inversion : Inversion Chromosomal segment breaks off and reattaches in reverse orientation to the same chromosome Translocation : Translocation Chromosome piece breaks off and reattaches to another nonhomologous chromosome Nondisjunction : Nondisjunction homologous chromosomes during meiosis fail to separate ↑ ↑ ↑ ↑ Slide 18: Point Mutations- Substitutions Frameshift Mutations- Insertions or deletions Gene Mutations RECAP Chromosome Mutations Deletions Inversions Translocation Nondisjunction Homework due TOMORROW! You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.