Mitochondria

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Mitochondria:

Mitochondria By Sathvik B.S 3 rd semester molecular biology Yuvaraja’s college Guide : Chandana K V.

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Rudolf Albert Kölliker Carl Benda Otto Heinrich Warburg

Contents:

Contents Introduction Endosymbiotic theory Structure Functions - Oxidation of carbohydrates - Oxidation of fatty acids - Oxidation of proteins Mitochondrial disorders - Labers Hereditary optic neuropathy - Leigh’s disease Conclusion References Acknowledgement

Endosymbiotic theory:

Endosymbiotic theory

Structure:

Structure

Functions:

Functions    

Oxidation of carbohydrates:

Oxidation of carbohydrates 1) Glycolysis :

2) Oxidative Decarboxylation ::

2) Oxidative Decarboxylation :

3) Krebs cycle ::

3) Krebs cycle :

Oxidation of fatty acids:

Oxidation of fatty acids

Oxidation of proteins:

Oxidation of proteins 1) Deamination :

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2) Transamination :

Oxidative phosphorylation:

Oxidative phosphorylation

Mitochondrial disorders:

1) Laber’s Hereditary optic neuropathy Acute LHON : Mitochondrial disorders

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2) Leigh’s disease

Slide 17:

Child with Leigh's disease

Conclusion:

Conclusion

References:

References P.S.Verma , V.K.Agarwal , (2001), “cell biology, genetics, molecular biology, evolution and ecology”, (15 th edition) A.L.Lehninger , (2008), “Biochemistry”, (2 nd edition) G.M.Cooper , R.E.Hausman , (2009), “The cell – A molecular approach”, (5 th edition) http://www.umdf.org/site/c.8qKOJ0MvF7LUG/b.8637485/k.8A22/Leighs_Disease.html http://biology.tutorvista.com/animal-and-plant-cells/mitochondria.html https://en.wikipedia.org/wiki/Mitochondrion

Acknowledgement:

Acknowledgement I thank our course co- ordinator Dr N.S.Devaki for providing me this opportunity to present this seminar; I thank my guide Chandana mam for her valuable guidance and support throughout the preparation of my seminar; I thank Vuppini mam for her guidance; I thank my seniors for their help; I thank you all for your patience.

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