# Pharmacology Review2008

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### Pharmacology Review :

Pharmacology Review Galveston College Rory Prue 2008

### Basic Drug Formula :

Basic Drug Formula Basic Formula: Volume to Administer =

### Dimensional Analysis :

Dimensional Analysis Dimensional analysis is a method that is useful for complex drug calculations. It is based on the same principles as simple conversions and the basic formula but does not require memorization of the dose-on-hand formula.

### Step 1 :

Step 1 Set up the equation. The unit of measurement desired in the answer (e.g. mLs, mgs, gtt/min, etc.) is placed to the left of the equal sign. The first factor is placed to the right of the equal sign and is the same unit as the answer.

### Step 2 :

Step 2 Cancel pairs of units of measures (i.e., labels) that appear in both the numerator and denominator. For components that are not fractions, the whole number is placed over 1. The only unit remaining after cancellation should be the unit of the answer. At the same time, reduce the fractions by dividing both numerators and denominators by a common number.

### Step 3 - 5 :

Step 3 - 5 Step 3: Multiply the numerators. Step 4: Multiply the denominators. Step 5 Divide the numerator by the denominator.

### Example 1 :

Example 1 You are to administer meperidine 50 mg IM. You have 75 mg of the drug in 1 mL of solution. How many milliliters will you give? Step 1: Set up the equation. The unit of measure desired in the answer is placed to the left of the equal sign. The first factor is the same unit as the answer.

### Example 1 continued :

Example 1 continued Step 2: Cancel like units and evenly divisible numbers. If the remaining unit is that of the answer the problem is set up correctly.

### Example 1 continued :

Example 1 continued Step 2 (cont): Simplify when possible. Step 3: Multiply numerators first and then denominators.

### Example 1 continued :

Example 1 continued Step 4: Divide the numerator by the denominator.

### Drug Infusion Formula :

Drug Infusion Formula Drug Infusion Formula: Drops/minute =

### IV Infusion Formula :

IV Infusion Formula IV Drip Formula: Drops per minute =

### Concentration Formula :

Concentration Formula To figure a drug’s concentration use the following formula:

### Solution Concentrations :

Solution Concentrations How do you figure the concentration of a solution when you are given the percentage of solute? For example you need to figure out what is the concentration of 2% Lidocaine?

### Practice Problem :

Practice Problem You have a drug that is a 3% solution. How many milligrams will be contained in 5 mLs?

### Practice Problem :

Practice Problem So if a 3% solution is a concentration of 30 mg per mL then we simply need to find out how many mgs are in 5 mL by multiplying 30mg by 5 which equals 150 mgs.

### Practice Problem :

The doctor orders you to administer 25 mg of drug XYZ. Drug XYZ comes supplied as 50 mg in 5 mLs. How many mLs should you administer? Practice Problem

### Practice Problem :

The doctor orders you to administer 300 mL of 0.9% NaCl over 2 hours using a microdrip administration set. How many drops per minute should you run the IV? Practice Problem

### Practice Problem :

You are to administer 5 mg/kg of Bretylium to your patient that weighs 216 lbs. Bretylium comes supplied as 500 mg in 5 mL. How many mLs of Bretylium should you administer? Practice Problem

### Practice Problem :

How many milligrams of drug ZYP are in 5 mLs if drug ZYP is a 3% solution? Practice Problem

### Practice Problem :

What is the concentration per milliliter of morphine sulfate if it is supplied as 10 mg in 10 mL? Practice Problem

### Practice Problem :

A physician has ordered the administration of 1mg/kg of a drug to a patient in cardiac arrest. The paramedic estimates that the patient weighs 175 pounds. The drug is packaged as 100 mg in a 5-mL prefilled syringe. How many milligrams of the drug are required? Practice Problem

### Practice Problem :

You receive an order to administer 20 mg of a drug. The drug comes packaged as 40 mg in a 4 mL prefilled syringe. How many milliliters will you administer? Practice Problem

### Practice Problem :

You have a 20% solution of a drug in 500 mL of IV fluid. The doctor orders you to administer 1.5g/kg of the drug to the patient over 1 hour. Your patient weighs 120 pounds. Supplied is a macro drip (15gtt/min) IV set. What is the concentration (g/mL) of the solution? Practice Problem

### Practice Problem :

You receive a drug order to administer activated charcoal to an 18-lb child who ingested a one-corrosive toxic substance. The dose is 1-2g/kg. How much should the child receive? Practice Problem

### Practice Problem :

You receive a drug order to administer adenosine to a 20-lb child with a symptomatic supraventricular tachycardia (SVT). The dose is 0.1-0.2 mg/kg. How much should the child receive? Practice Problem

### Practice Problem :

Practice Problem You receive a drug order to administer 150 mg amiodarone via slow IV drip over 10 minutes. You have 150 mg of amiodarone, a 50 mL bag of normal saline, and a 10-gtt/mL macrodrip set. Determine the concentration and caluclate the drip rate.

### Ipratropium :

Ipratropium Generic or trade name? Indication? Dosage? Contraindications?

### Lidocaine :

Lidocaine Classification? Dosage? Indications? Precautions or contraindications?

### Magnesium Sulfate :

Magnesium Sulfate Classification? Dosage? Indications? Precautions or contraindications?

### Methylprednisone :

Methylprednisone Classification? Trade Name? Dosage? Indications? Precautions or contraindications?

### Versed :

Versed Classification? Generic name? Dosage? Indications? Precautions or contraindications?

### Nitroglycerine :

Nitroglycerine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Narcan :

Narcan Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Morphine :

Morphine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Procainamide :

Procainamide Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Promethazine :

Promethazine Classification? Trade name? Dosage? Indications? Precautions or contraindications? Side effects?

### Calcium Chloride :

Calcium Chloride Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Dextrose :

Dextrose Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Diazepam :

Diazepam Classification? Trade name? Dosage? Indications? Precautions or contraindications? Side effects?

### Cardizem® :

Cardizem® Classification? Generic name? Dosage? Indications? Precautions or contraindications? Side effects?

### Diphenhydramine :

Diphenhydramine Classification? Trade name? Dosage? Indications? Precautions or contraindications? Side effects?

### Dobutamine :

Dobutamine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Dopamine :

Dopamine Classification? Trade name Dosage? Indications? Precautions or contraindications? Side effects?

### Epinephrine :

Epinephrine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Fentanyl :

Fentanyl Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Furosemide :

Furosemide Classification? Trade name? Dosage? Indications? Precautions or contraindications? Side effects?

### Glucagon :

Glucagon Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Haloperidol :

Haloperidol Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Thiamine :

Thiamine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Succinylcholine :

Succinylcholine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Racemic Epinephrine :

Racemic Epinephrine Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Sodium Bicarbonate :

Sodium Bicarbonate Classification? Dosage? Indications? Precautions or contraindications? Side effects?

### Vasopressin :

Vasopressin Classification? Dosage? Indications? Precautions or contraindications? Side effects?