Basics Of Pharmacology Slide

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Basics of pharmacology very much essential for pharma sales beginners!

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Slide 1:

Basics Of Pharmacology Pranab Chatterjee

Slide 2:

Content Bioavailability Cmax Tmax MEC Plasma ½ life Objective of the training. What is pharmacology ? What is drug ? Pharmacy. Pharmacodynamics. Pharmacokinetics. Route of drug administration. Factors Affecting drug administration. Important Notes-

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Objective To understand the basic of pharmacology. Helps to understand the drugs. Helps to develop effective sales approach.

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What is pharmacology ? Branch of medicine concerned with the uses, effects, and mode of action of drugs.

What is drug ?:

What is drug ? Drug is an active chemical ingredients used for diagnosis, prevention, treatment, and cure of diseases.

What is pharmacy ?:

What is pharmacy ? Science of identification, selection, preservation, standardisation, compounding and dispensing of medicine.

What is pharmacokinetics ?:

What is pharmacokinetics ? What body does to the drug.

What is pharmacodynamics ?:

What is pharmacodynamics ? What drug does to the body.

Route of Drug Administration:

Route of Drug Administration Local Routes, and Systemic Routes.

Routes Of Drug Administration:

Routes Of Drug Administration Local Routes Topical Routes Skin, and Mucous Membrane. 2. Deeper Tissues, and 3. Arterial Supply.

Routes Of Drug Administration:

Routes Of Drug Administration Systemic Routes Oral Sublingual or buccal Rectal Cutaneous Inhalation Nasal

Routes Of Drug Administration:

Routes Of Drug Administration Systemic Routes Parentral Subcutaneous Intramuscular, and intravenous

Factors Affecting Drug Absorption:

Factors Affecting Drug Absorption Drug Related Factors. Patients Related Factors.

Factors Affecting Drug Absorption:

Factors Affecting Drug Absorption Drug Related Factors Physical State. Lipid Solubility. Dosage Form. Disintegration Time/ Dissolution rate.

Factors Affecting Drug Absorption:

Factors Affecting Drug Absorption Patient Related Factors ph of gastrointestinal tract. GI transit time. Presence of other agents, and Disease state.

Important Notes:

Important Notes Blood Brain Barrier It prevents/ restricts the entry of chemical substance to brain. Lipid soluble drugs can easily penetrate BBB.

Important Notes:

Important Notes Metabolism/ Biotransformation Process of conversion of drug into simple chemical and water soluble form.

Important Notes:

Important Notes Prodrug Inactive form of drug. Converted into active drug when they are in the body.

Important Notes:

Important Notes Bioavailability Amount of drug available in blood in unchanged form.

Important Notes:

Important Notes Cmax Maximum concentration of drug available in blood.

Important Notes :

Important Notes Tmax Time taken by drug to achieve maximum concentration.

Important Notes:

Important Notes MEC (Minimum Effective Concentration) Lowest concentration of drug available in blood.required to produce therapeutic effect.

Important Notes:

Important Notes Plasma Half Life(t/2) It is the time where plasma concentration of drug reduced to half of its original value.

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Thank You !!!

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