2. Generic vs. Brand Names

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Slide 1:

Generic vs Brand Names and the Main Classes of Antimalarial Medicines technical presentation 1of 4

Slide 2:

Who here has had malaria? What medicines did you use to treat it?

Main Goal: To be able to Accurately Complete the Tablet & Suppository and Non-tablet Audit Sheets:

Main Goal: To be able to Accurately Complete the Tablet & Suppository and Non-tablet Audit Sheets By the end of this presentation you should be able to: Recognize the generic name and brand name on a medicine package and distinguish between the two names Identify the manufacturer and country of manufacture on a medicine package Determine if a medicine has 1 active ingredient or 2 or more active ingredients Recognize the most common generic names of antimalarial medicines

What is a Generic Drug Name? A medication is usually given two names: :

What is a Generic Drug Name? A medication is usually given two names: Generic name Describes what the medication is made from: active ingredient Official standardized name given to a pharmaceutical substance, by WHO Brand name The name the manufacturer decides to call their product and is the name they sell the product under Proprietary name; trade name Not all medicines have a brand: Unbranded generics

Distinguishing Between Generic Name & Brand Name:

Distinguishing Between Generic Name & Brand Name For medicines: The generic name will sound like a chemical name The brand name will often have ® or ™ written after it The brand is sometimes written very large and distinctly on the package Be sure to include “Pediatric”, “Adult”, “Junior” in the Brand name

Non-Medicine Example: Generic vs. Brand Name:

Non-Medicine Example: Generic vs. Brand Name When you go to the store to buy milk, there are many different ‘ brands ’ of milk you can buy like ‘Nestle’, ‘Bonnet Blue’ or ‘Jago’. However, the contents in the carton and therefore the generic name for all the different ‘brands’ are the same: milk.

Medicine Example: Generic vs. Brand Names:

Medicine Example: Generic vs. Brand Names Generic Name Paracetamol Brand names Panadol Calpol Perdolan And others

Other Examples of a Generic Drug and Brand Names:

Other Examples of a Generic Drug and Brand Names ?

Manufacturer:

Manufacturer The company that makes a product The manufacturer will always be listed on the packaging of the medicine More than one company may be listed on the package. We are interested in the ‘parent company’

Country of Manufacturer:

Country of Manufacturer Sometimes, the city will be listed instead of the country. For example, Beijing For American manufacturers, sometimes the state will also be listed For example, New Jersey, U.S.A.

One Active Ingredient vs. Two Active Ingredients:

One Active Ingredient vs. Two Active Ingredients A medication to treat malaria can have 1 active ingredient Example: Mefloquine A medication to treat malaria can have 2 or more active ingredients Example: Artesunate/Mefloquine Both active ingredients are listed as the generic name

A Closer Look at our Examples 1 vs. 2 :

A Closer Look at our Examples 1 vs. 2

Medicines with 2 Active Ingredients: 2 Possible Presentations :

Medicines with 2 Active Ingredients: 2 Possible Presentations The 2 active ingredients are combined into a single tablet The 2 active ingredients are contained in 2 separate tablets , but packaged together in the same blister

To review::

To review: What are the 4 things that we have discussed that we should find on a package of medicine? Generic Name Brand Name Manufacturer Country of Manufacture Which of these may not exist for every medicine? Brand name

What are the Most Common Antimalarial Medications (by Generic Name)?:

What are the Most Common Antimalarial Medications (by Generic Name)?

Basic Set of Antimalarial Medicines by Generic Name: :

Basic Set of Antimalarial Medicines by Generic Name: Chloroquine Sulfadoxine Sulfamethoxypyrazine Pyrimethamine Mefloquine Amodiaquine Quinine Halofantrin Naphthoquine

Another Set of Common Antimalarial Generic Names: Artemisinin Monotherapies:

Another Set of Common Antimalarial Generic Names: Artemisinin Monotherapies Artemisinin Artemether* Artesunate* Dihydroartesmisinin Artemotil *Most common

Another Set of Common Antimalarial Generic Names : Artemisinin-based Combination Therapy (ACT) :

Another Set of Common Antimalarial Generic Names : Artemisinin-based Combination Therapy (ACT) 1 Medicine, 2 Active Ingredients 1 of the active ingredients is either: - Artemether - Artemisinin - Artesunate - Artemotil - Dihydroartemisinin General structure of all ACTs: ARTEMISININ MONOTHERAPY + PARTNER DRUG

Examples of Common ACTs::

Examples of Common ACTs: ARTEMISININ DERIVATIVE + PARTNER DRUG: Artesunate / Amodiaquine Artesunate / Mefloquine Artesunate / Sulfadoxine/ Pyrimethamine Artemether / Lumefantrine Dihydroartemisinin / Piperquine phosphate Artemisinin / Naphthoquine

Review: Generic Names of Antimalarial Medicines :

Review: Generic Names of Antimalarial Medicines Chloroquine Sulfadoxine Sulfamethoxypyrazine Pyrimethamine Mefloquine Amodiaquine Quinine Halofantrine Naphthoquine Artemisinin Artemether Artesunate Dihydroartemisinin Artemotil And Combinations Complete list is given in the Fieldworker’s Manual

Important Point:

Important Point If you know the generic names mentioned on the previous slides, you can determine whether ANY medicine is an antimalarial medication!

What About Other Medicines used to Treat Malaria?:

What About Other Medicines used to Treat Malaria? There are different classes of medicines that might be used to treat malaria, but are not anti-malarial medications? We are only interested in medicines that exclusively treat malaria Other classes: Antibiotics (kill bacteria) Antipyretics (pain relievers)

Examples of Other Medicines that are Sometimes Given to Treat Malaria, but are not Antimalarial Medicines:

Examples of Other Medicines that are Sometimes Given to Treat Malaria, but are not Antimalarial Medicines ANTIBIOTICS Tetracycline Doxycycline Doxymicin And others ANTIPYRETICS Tetracycline Doxycycline Doxymicin And others

Audit Sheets: 2 Types - Tablet & Suppository - Non-Tablet Audit Sheet :

Audit Sheets: 2 Types - Tablet & Suppository - Non-Tablet Audit Sheet 1. Generic name 4. Brand name 5. Manufacturer 5a . Country of manufacturer

ACTIVITY BREAK #1:

ACTIVITY BREAK #1 We will pass out an antimalarial to everyone. On your activity sheet (not the audit sheet), record: - Generic name - Brand name - Manufacturer - Country of Manufacturer DO NOT RECORD STRENGTH!! Switch with the person next to you and repeat Hold on to the medicines after the activity. You will use them in another activity If there is no brand name, also record the generic name in the Brand name space.

ACTIVITY BREAK 1 (cont.):

ACTIVITY BREAK 1 (cont.) Same instructions Record information using a new set of antimalarials we pass out to you

On a Box of Medicine, Some Active Ingredients are Presented with Another Chemical :

On a Box of Medicine, Some Active Ingredients are Presented with Another Chemical Example: Mefloquine is normally presented as Mefloquine hydrochloride This is still just one active ingredient: MEFLOQUINE

When the active ingredient is presented with a chemical, the label will sometimes list the active ingredient alone as the ‘base’ :

When the active ingredient is presented with a chemical, the label will sometimes list the active ingredient alone as the ‘ base’ - Mefloquine hydrochloride Mefloquine base - Chloroquine Phosphate Chloroquine base

The most common chemicals added to active ingredients: hydrochloride, sulphate, phosphate :

The most common chemicals added to active ingredients: hydrochloride, sulphate, phosphate Common combinations: Mefloquine hydrochloride Amodiquine hydrochloride Chloroquine hydrochloride, sulphate or phosphate Quinine hydrochloride or sulphate

Slide 30:

Q: Why is it important to be able to recognize the names of the ‘extra’ chemicals associated with the active ingredient? A: To be able to distinguish these extra chemicals and know they are not an additional active ingredient

Questions:

Questions What is a generic name? For a medicine, is there a difference between the generic name and active ingredient? How many active ingredients can there be in a medicine? What are the 3 ‘extra chemicals’ that can be listed with the generic name? What word is sometimes used on a medicine package to describe the active ingredient without the extra chemical? How can you distinguish the generic name from the brand name? For antimalarial medications, there are basic set of 12 active ingredients. Name them.

Answers:

Answers The generic name describes the active ingredient(s) There is no difference between active ingredient and generic name for medicine 1 or more active ingredients can be in a medicine Some medicines have an extra chemical in the generic name. This is not an extra active ingredient. Hydrochloride Sulfate Phosphate ‘Base’ is sometimes used on a medicine package to describe the active ingredient without the extra chemical. Brand name may be written with ® or™. Generic name will sound like a chemical name.

You Should Now Be Able To::

You Should Now Be Able To: Determine the generic name from a medicine package Determine the brand name from a medicine package Determine how many active ingredients are in a medicine When an active ingredient is presented with an extra chemical, to be able to distinguish it from another active ingredient Identify the basic set of generic names of antimalarial medicines

Slide 34:

Questions ?

Activity 2:

Activity 2 We need 4 volunteers Each person will answer some questions about a medicine based on what we just learned If you do not know the answer, that is okay. You can ask a friend to help you.

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