RATIONAL USE OF MEDICINES

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RATIONAL USE OF DRUGS:

RATIONAL USE OF DRUG S DR.P. CHAKRAVARTY MBBS,DMCH,DHHM,MD ASSTT.PROF. DEPTT.OF PHARMACOLOGY, GAUHATI MEDICAL COLLEGE, GUWAHATI ACADEMIC CO-ORDINATOR, NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION & RESEARCH(NIPER), GUWAHATI

WHO-INDIA ESSENTIAL DRUG PROGRAMME:

WHO-INDIA ESSENTIAL DRUG PROGRAMME IMPROVING THE AVAILABILITY OF SAFE & EFFECTIVE DRUGS ESTABLISHING A QUALITY CONTROL & ASSURANCE SYSTEM IMPROVING PROCUREMENT, STORAGE & DISTRIBUTION SYSTEM FOR MEDICINES ENCOURAGING RATIONAL PRESCRIBING & USE OF MEDICINES

WHO-INDIA ESSENTIAL DRUG PROGRAMME:

WHO-INDIA ESSENTIAL DRUG PROGRAMME STRENGTHENING & EXPANDING HEALTH EDUCATION PROGRAMMES INCREASING PATIENT AWARENESS RESEARCH & MONITORING ON ALL ASPECTS OF DRUG USE

WHO-INDIA ESSENTIAL DRUG PROGRAMME:

WHO-INDIA ESSENTIAL DRUG PROGRAMME DEVELOPING OF A DRUG POLICY SELECTION OF A LIST OF ESSENTIAL DRUGS ESTABLISHMENT OF A POOLED PROCUREMENT DEVELOPMENT OF A QUALITY ASSURANCE SYSTEM TRAINING IN RATIONAL PRESCRIBING

WHO-INDIA ESSENTIAL DRUG PROGRAMME:

WHO-INDIA ESSENTIAL DRUG PROGRAMME PROVISION OF OBJECTIVE INFORMATION TO DOCTORS ABOUT MEDICINES RESEARCH LEADING TO MONITORING & EVALUATION OF THE PROGRAMME HUMAN RESOURCE DEVELOPMENT IN THE FIELD OF RATIONAL USE OF DRUGS PROVISION OF INFORMATION TO PATIENTS FOR IMPROVING PATIENT COMPLIANCE.

PROCESS OF RATIONAL PRESCRIBING:

PROCESS OF RATIONAL PRESCRIBING 1. DEFINE THE PATIENT’S PROBLEM. 2. SEPECIFY THE THERAPEUTIC OBJECTIVE. 3. CHOOSE A TREATMENT OF PROVEN EFFICACY , SAFETY , SUITABILITY AND COST FROM DIFFERENT ALTERNATIVES (VERIFY THE SUITABILITY OF YOUR ‘P’ TRTEATMENT.)

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YOU ARE RESPONSIBLE

PROCESS OF RATIONAL PRESCRIBING:

PROCESS OF RATIONAL PRESCRIBING 4. START THE TREATMENT BY WRITING AN ACCURATE PRESCRIPTION AND PROVIDING THE PATIENT WITH CLEAN INFORMATION AND INSTRUCTIONS/WARNINGS. 5. AFTER SOME TIME MONITOR THE RESULTS AND STOP TREATMENT IF THE PROBLEM HAS BEEN SOLVED.

QUALITY OF A THERAPEUTIC DECISION CAN BE MEASURED BY:

QUALITY OF A THERAPEUTIC DECISION CAN BE MEASURED BY CLINICAL OUTCOME (EFFICACY, TOXICITY, ALLERGY ETC.) FUNCTIONAL STATUS OF PATIENT OVEREALL PATIENT SATISFACTION COSTS (DIRECT & INDIRECT)

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SIDE EFFECTS

ADVERSE DRUG EVENTS ARE:

ADVERSE DRUG EVENTS ARE COMMON OFTEN PREVENTABLE ADD SIGNIFICANTLY TO LENGTH OF STAY AND COST OF HOSPITALIZATION MAY BE A RELATIVELY FREQUENT CAUSE OF DEATH IN HOSPITAL PATIENTS

PHYSICIAN ERRORS IN DRUG PRESCRIBING ARE MOST COMMONLY RELATED TO:

PHYSICIAN ERRORS IN DRUG PRESCRIBING ARE MOST COMMONLY RELATED TO FAILING TO COMPENSATE FOR ABNORMAL RENAL OR HEPATIC FUNCTION FAILURE TO DETERMINE PRIOR HISTORY OF DRUG ALLERGY USING THE WRONG DRUG NAME AND DOSAGE FORM USING MISUNDERSTOOD ABBREVIATIONS CALCULATING DOSES INCORRECTLY

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PATIENT VS DOCTOR

APPROACH TO RATIONAL THERAPEUTICS:

APPROACH TO RATIONAL THERAPEUTICS SET THE LEGITIMATELY EXPECTED CLINICAL EFFECTS OF THERAPY (ENDPOINTS DEMONSTRATING EFFICACY AND LOWER LIMITS OF TOXICITY) BEFORE STARTING THERAPY. USE THESE OBJECTIVES TO MONITOR DRUG EFFECTS AND TO SIGNAL THE NEED FOR QUALITATIVE OR QUANTITATIVE CHANGES IN THERAPY.

TO ERR IS HUMAN BUT IT CAN BE AVOIDED WITH R.U.D.:

TO ERR IS HUMAN BUT IT CAN BE AVOIDED WITH R.U.D. COMMUNICATION KNOWLEDGE INTELLIGENCE COMMON SENSE BEHAVIOUR DOCUMENTATION ANALYSIS PRECAUTIONS

SIX STEPS TO A RATIONAL THERAPEUTIC DECISION ARE:

SIX STEPS TO A RATIONAL THERAPEUTIC DECISION ARE MAKING AN ACCURATE DIAGNOSIS UNDERSTANDING THE PATHO-PHYSIOLOGY OF DISEASE REVIEWING THE MENU OF PHARMACOTHERAPEUTIC OPTIONS SELECTING PATIENT SPECIFIC DRUG AND DOSE SELECTING END POINTS TO FOLLOW MAINTAINING A THERAPEUTIC ALLIANCE WITH THE PATIENT

PRINCIPLE:

PRINCIPLE EACH PATIENT IS UNIQUE IN RESPONSE TO PARTICULAR DRUGS; THEREFORE, EACH PATIENT POSES UNIQUE CHALLENGES TO THE PHYSICIAN ATTEMPTING TO PRACTICE RATIONAL THERAPEUTICS

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IF YOU PRACTICE RUD

PATIENTS DIFFER FROM ONE ANOTHER WITH RESPECT TO THEIR:

PATIENTS DIFFER FROM ONE ANOTHER WITH RESPECT TO THEIR PHARMACOKINETICS PHARMACODYNAMICS AGE GENDER PREGNANCY OR BREAST FEEDING PHARMACO-GENETIC PHENOTYPE RENAL FUNCTION HEPATIC FUNCTION CONCURRENT DRUGS CONCURRENT DISEASES PRIOR ADVERSE DRUG REACTIONS OR DRUG ALLERGIES

THANK YOU:

THANK YOU PLEASE ASK ME IF YOU HAVE QUERIES ? dr_pinaki@yahoo.com amc.pvpighy@yahoo.com 03612912120 (PHARMACOVIGILLANCE CENTRE IN GMCH) 9859411612

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HAVE A NICE DAY

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