SELECTION AND EVALUATION OF PACKAGING MATERIALS

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SELECTION AND EVALUATION OF PACKAGING MATERIALS:

SELECTION AND EVALUATION OF PACKAGING MATERIALS Submitted by Neetu Khatri M.Pham 1 st Sem. Pharmaceutics

INTRODUCTION:

INTRODUCTION PRIMARY PACKAGING SECONDARY PACKAGING CHARACTERISTICS OF PACKAGING

SELECTION OF PACKAGING MATERIALS:

SELECTION OF PACKAGING MATERIALS Selection of packaging materials according to containers Selection of containers according to their shapes Selection of packaging materials according to product Characteristics

SELECTION OF PACKAGING MATERIALS ACCORDING TO CONTAINERS :

SELECTION OF PACKAGING MATERIALS ACCORDING TO CONTAINERS GLASS PLASTIC

SELECTION OF PACKAGING MATERIALS ACCORDING TO CONTAINERS :

SELECTION OF PACKAGING MATERIALS ACCORDING TO CONTAINERS METAL CLOSURES AND LINERS

SELACTION OF PACKAGING MATERIALS ACCORDING TO THEIR SHAPES:

SELACTION OF PACKAGING MATERIALS ACCORDING TO THEIR SHAPES Glass / polyethylene bottles Narrow mouth Wide mouth Dropper bottles/ droptainers Collapsible tubes Ampoules Vials Polythene packets for i.v . fluid. Polythene / glass bottle for i.v . fluids Aerosol containers

SELECTION OF PACKAGING MATERIALS ACCORDING TO PRODUCT CHARACTERISTICS:

SELECTION OF PACKAGING MATERIALS ACCORDING TO PRODUCT CHARACTERISTICS FACTORS WHICH CONSIDER DURING PACKAGING Hygroscopicity Physical degradation Chemical degradation Drug release properties

PACKAGING MATERIAL FOR SOLID DOSAGE FORM :

PACKAGING MATERIAL FOR SOLID DOSAGE FORM Single dosage for oral administration Powder for oral administration or local application

PACKAGING MATERIAL FOR SOLID DOSAGE FORM :

PACKAGING MATERIAL FOR SOLID DOSAGE FORM Effervescent granules Single non oral dosage form

SELECTION OF PACKAGING MATERIAL FOR SEMI SOLID (TOPICAL) DOSAGE FORMS :

SELECTION OF PACKAGING MATERIAL FOR SEMI SOLID (TOPICAL) DOSAGE FORMS Semi solid dosage forms include aerosols, creams, emulsions, gels, lotions, ointments, pastes

SELECTION OF PACKAGING MATERIAL FOR LIQUID DOSAGE FORMS :

SELECTION OF PACKAGING MATERIAL FOR LIQUID DOSAGE FORMS Liquid oral dosage forms Liquid Non – Oral Dosage Forms

SELECTION OF PACKAGING MATERIAL FOR BLOOD PRODUCTS:

SELECTION OF PACKAGING MATERIAL FOR BLOOD PRODUCTS

EVALUATION OF GLASS CONTAINERS:

EVALUATION OF GLASS CONTAINERS Hydrolytic resistance test Powdered glass test Whole container test Light transmission test

EVALUATION TESTS ON PLASTIC CONTAINERS :

EVALUATION TESTS ON PLASTIC CONTAINERS For Non Paranteral Preparations Leakage test Collapsibility test For Oral Liquids Clarity of aqueous extract Non-volatile residue For Parenteral preparations Leakage Test Collapsibility Test Clarity and Colour of solution

EVALUATION TESTS ON PLASTIC CONTAINERS :

EVALUATION TESTS ON PLASTIC CONTAINERS Acidity and Alkalinity Test Transparency Light Absorption Reducing Substances Biological Test For Ophthalmic Preparations Leakage test:- Collapsibility test: Clarity of aqueous extract

PowerPoint Presentation:

Non-volatile residue Biological tests Eye irritation test EVALUATION TEST ON METAL CONTAINER For Ophthalmic Ointment

EVALUATION TEST ON RUBBER CLOSURES :

EVALUATION TEST ON RUBBER CLOSURES Appearance of solution pH of aqueous extract Light absorption Reducing substances Heavy Metals Residue on evaporation Volatile sulphides Sterilisation test Fragmentation test Self- sealability Biological Tests

EVALUATION TEST ON CONTAINER FOR BLOOD AND BLOOD COMPONENTS :

EVALUATION TEST ON CONTAINER FOR BLOOD AND BLOOD COMPONENTS Resistance to centrifugation Resistance to stretch Leakage Vapour permeability Emptying under pressure Speed of filling Resistance to temperature variations Transparency Extractable matter

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