logging in or signing up Methyl Alcohol Poisoning neeraj525 Download Post to : URL : Related Presentations : Let's Connect Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Copy embed code: Embed: Flash iPad Dynamic Copy Does not support media & animations Automatically changes to Flash or non-Flash embed WordPress Embed Customize Embed URL: Copy Thumbnail: Copy The presentation is successfully added In Your Favorites. Views: 620 Category: Product Traini.. License: All Rights Reserved Like it (0) Dislike it (0) Added: June 24, 2012 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript Methyl Alcohol Poisoning: Methyl Alcohol Poisoning Presented by- Dr. Neeraj Kumar M.O. CHC Pooh, Kinnaur Medical Officer De-addiction Training at Parimahal , Shimla 23/06/2012 6/24/2012 1Case Study: Case Study Last Sunday, when I was on emergency duty at Regional Hospital Reckongpeo, Police brought 25 yr male with altered sensorium. There was alleged H/O alcohol intake with other two friends . 6/24/2012 2PowerPoint Presentation: They started drinking some country made liquor at 8:00 am. At 10:00 am he managed to come out of his house and told people that his two friends are unconscious and he is also feeling drowsy & c/o palpitation, pain abdomen and vomiting. People went to his room and found that two other had already died. They informed police and brought the patient to ER. 6/24/2012 3PowerPoint Presentation: After 6 hrs in hospital, when he gained some consciousness he c/o diminution of vision. Pupils B/L reacting to light. But was unable to count fingers even at 50 cm. 6/24/2012 4PowerPoint Presentation: What is the case? 6/24/2012 5Toxicity: Toxicity 10 mL of pure methanol can cause permanent blindness by destruction of the optic nerve 30 mL is potentially fatal, although the median lethal dose is typically 100 mL 6/24/2012 6PowerPoint Presentation: 6/24/2012 7SIGN & SYMPTOMS: SIGN & SYMPTOMS Headache, dizziness, & vertigo Nausea, vomiting & epigastric pain Cardiac functions are depressed Muscular weakness, dyspnoea & cyanosis Visual disturbances - blurred vision - photophobia - optic neuritis 6/24/2012 8PowerPoint Presentation: Subnormal temperature Delirium& coma (2-3 days) Bradycardia & KUSSMAUL BREATHING Urine is strongly acidic and contains - albumin - acetone - formic acid Death occurs from respiratory failure 6/24/2012 9Treatment: Treatment Unabsorbed Methanol should be removed by gastric lavage . Supportive Measures: ■Correction of Acidosis ■Control of seizures ■Maintenance of nutrition ■Alkalization of urine enhances excretion of formic acid 6/24/2012 10Specific Measures: Specific Measures Administration of Ethanol to saturate alcohol dehydrogenase. 5 % solution of Ethanol is prepared loading dose 15 ml/kg maintenance dose 2-3 ml/kg/hour orally. Can also be given intravenously. Folic acid has been used to enhance conversion of formate to carbon dioxide and water. The dose is 50 mg IV 4 hourly for 24 hours. 6/24/2012 11PowerPoint Presentation: Hemodialysis enhances elimination of Methanol and Formic acid and is indicated when Methanol levels exceed 50 mg/dl. 4-methylpyrazole , an inhibitor of alcohol dehydrogenase . 6/24/2012 12PowerPoint Presentation: 6/24/2012 13PowerPoint Presentation: 6/24/2012 14 Pooh, Kinnaur Thank you You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.