logging in or signing up Pharm Team Ly - Excretion missuyenly Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 363 Category: Education License: All Rights Reserved Like it (2) Dislike it (0) Added: February 13, 2009 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... By: suryatejabang (14 month(s) ago) that is really good..... can u give it..... really a wonderful ppt Saving..... Post Reply Close Saving..... Edit Comment Close By: sadia06 (24 month(s) ago) hey, i need this ppt can u plz giv this to me, its really good work Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide 1: Pharmacology: Excretion Excretion Definition Processes of Urine Excretion Glomerular Filtration Passive Filtration Active Tubular Filtration Nursing Implications Presented by Team Ly Pharmacology: Excretion : Overview Definition of Excretion: Removal of drugs from the body Kidneys The most important organ in drug excretion Therefore, most drugs exit the body in urine Pharmacology: Excretion Overview Nursing Implications Excretion Process Slide 3: Processes of Urine Excretion 1. Glomerular Filtration 2. Passive Tubular Reabsorption 3. Active Tubular Secretion The combination of these processes determine the amount of drugs removed from the body in urine. Excretion Nursing Implications Excretion Process Overview Pharmacology: Excretion Pharmacology: Excretion : Pharmacology: Excretion Simplifying the concepts of Urine Excretion… Let’s pretend that… Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine Slide 5: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 6: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 7: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 8: • The ability and speed of the kidneys to remove drugs from the body can affect therapeutic response • If removal is fast, the duration of the therapeutic response will be short. A larger dosage or shorter dosage interval may be needed to maintain therapeutic response. • If a patient is having trouble removing the drug, a smaller dosage may be necessary. • An understanding of how much of the drug gets removed, determines how much you need to replace to maintain therapeutic response. • Toxic levels can be prolonged if the body cannot eliminate the drug. Nursing Implications Nursing Implications Excretion Process Overview Pharmacology: Excretion Excretion Summary : Excretion Summary Slide 10: References Hoehn, K. & Marieb, N. E. (2007). Human Anatomy & Physiology. (7th ed.). San Francisco: Pearson. All Refer. (2009). ADAM Kidney Anatomy. Retrieved February 5, 2009 from http://medicalimages.allrefer.com/large/kidney-anatomy.jpg Lehne, R. (2007). Pharmacology for Nursing Care. (6th ed.). St. Louis, MO: Saunders Elsevier. Lewis, S.L., Heitkemper, M.M., Dirksen, S.R., O'Brien, P.G., & Bucher, L. (2007). Medical-Surgical Nursing: Assessment and Management of Clinical Problems. (7th ed.). St. Louis, MO: Elsevier Health Science. Pharmacology: Excretion You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
Pharm Team Ly - Excretion missuyenly Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 363 Category: Education License: All Rights Reserved Like it (2) Dislike it (0) Added: February 13, 2009 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... By: suryatejabang (14 month(s) ago) that is really good..... can u give it..... really a wonderful ppt Saving..... Post Reply Close Saving..... Edit Comment Close By: sadia06 (24 month(s) ago) hey, i need this ppt can u plz giv this to me, its really good work Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide 1: Pharmacology: Excretion Excretion Definition Processes of Urine Excretion Glomerular Filtration Passive Filtration Active Tubular Filtration Nursing Implications Presented by Team Ly Pharmacology: Excretion : Overview Definition of Excretion: Removal of drugs from the body Kidneys The most important organ in drug excretion Therefore, most drugs exit the body in urine Pharmacology: Excretion Overview Nursing Implications Excretion Process Slide 3: Processes of Urine Excretion 1. Glomerular Filtration 2. Passive Tubular Reabsorption 3. Active Tubular Secretion The combination of these processes determine the amount of drugs removed from the body in urine. Excretion Nursing Implications Excretion Process Overview Pharmacology: Excretion Pharmacology: Excretion : Pharmacology: Excretion Simplifying the concepts of Urine Excretion… Let’s pretend that… Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine Slide 5: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 6: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 7: Water from Faucet = Blood Flow Sponge = Blood Water = Drugs Once water (drugs) leaves the sponge, its in urine GLOMERULAR FILTRATION Running water from the faucet pushes water through and out of the sponge. Blood flow pushes drugs from the blood through the glomerular capillaries into the tubule, en route to become urine. * Drugs move from blood to urine. PASSIVE TUBULAR RESORPTION The sponge reabsorbs water. Drugs reabsorb from the tubule back into the blood. * Drugs move from urine to blood. ACTIVE TUBULAR SECRETION Water is squeezed out of sponge. Drugs pumped out of blood by active transport systems back into tubules to be excrete in urine. * Drugs move from blood to urine. Drugs Drugs Drugs Slide 8: • The ability and speed of the kidneys to remove drugs from the body can affect therapeutic response • If removal is fast, the duration of the therapeutic response will be short. A larger dosage or shorter dosage interval may be needed to maintain therapeutic response. • If a patient is having trouble removing the drug, a smaller dosage may be necessary. • An understanding of how much of the drug gets removed, determines how much you need to replace to maintain therapeutic response. • Toxic levels can be prolonged if the body cannot eliminate the drug. Nursing Implications Nursing Implications Excretion Process Overview Pharmacology: Excretion Excretion Summary : Excretion Summary Slide 10: References Hoehn, K. & Marieb, N. E. (2007). Human Anatomy & Physiology. (7th ed.). San Francisco: Pearson. All Refer. (2009). ADAM Kidney Anatomy. Retrieved February 5, 2009 from http://medicalimages.allrefer.com/large/kidney-anatomy.jpg Lehne, R. (2007). Pharmacology for Nursing Care. (6th ed.). St. Louis, MO: Saunders Elsevier. Lewis, S.L., Heitkemper, M.M., Dirksen, S.R., O'Brien, P.G., & Bucher, L. (2007). Medical-Surgical Nursing: Assessment and Management of Clinical Problems. (7th ed.). St. Louis, MO: Elsevier Health Science. Pharmacology: Excretion