PICO1.14.2011

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From Clinical Problem to Research Question : 

From Clinical Problem to Research Question

P: Population : 

P: Population Dual dx: SMI and substance use Triple dx: Dual dx + HIV/HCV General Population HIV: 0.5% (McQuillan & Kruszon-Moran, 2008) HCV: 1.6% (Armstrong, et al., 2006) SMI HIV: 1.7-5.0% (Rosenberg, et al., 2001) HCV: 19% (Rosenberg, et al., 2001)

P: Population : 

P: Population Dual dx: SMI and substance use Triple dx: Dual dx + HIV/HCV General Population HIV: 0.5% (McQuillan & Kruszon-Moran, 2008) HCV: 1.6% (Armstrong, et al., 2006) SMI HIV: 1.7-5.0% (Rosenberg, et al., 2001) HCV: 19% (Rosenberg, et al., 2001)

Healthy Living Project (HLP) : 

Healthy Living Project (HLP) I: Intervention HLP Strengths Effective for reducing transmission risk behaviors (both sexual and substance related) Effects sustained over time Weaknesses Study did not measure mental illness beyond depressive symptoms Unknown if effects would generalize to SMI population Intervention Components 15 - 90-minute sessions were grouped into 3 modules. Delivered over 2 months, with 3 months between modules for a total duration of 12 months. Private settings in community-based organizations and clinics Delivered by ethnically diverse, gender-matched female and male facilitators with experience as social workers, counselors, therapists, or community-based service providers

Healthy Living Project (HLP) : 

Healthy Living Project (HLP) I: Intervention HLP Strengths Effective for reducing transmission risk behaviors (both sexual and substance related) Effects sustained over time Weaknesses Study did not measure mental illness beyond depressive symptoms Unknown if effects would generalize to SMI population Intervention Components 15 - 90-minute sessions were grouped into 3 modules. Delivered over 2 months, with 3 months between modules for a total duration of 12 months. Private settings in community-based organizations and clinics Delivered by ethnically diverse, gender-matched female and male facilitators with experience as social workers, counselors, therapists, or community-based service providers

C: Control Condition : 

C: Control Condition In HLP – Delayed treatment condition Treatment as usual also standard

O: Outcomes : 

O: Outcomes HIV and HCV transmission risk acts 90 day time frame Acts of unprotected vaginal, anal, or oral sex Sum of number of days of substance use per week/month (15 categories i.e. MDMA, cocaine/crack, heroin, etc.)

Research Question : 

Research Question Among SMI diagnosed with HIV and/or HCV (P), is the Healthy Living Project intervention (I) more effective than usual care in the community (C) for reducing HIV/HCV transmission risk behaviors (O)?

Research Question : 

Research Question Among SMI diagnosed with HIV and/or HCV (P), is the Healthy Living Project intervention (I) more effective than usual care in the community (C) for reducing HIV/HCV transmission risk behaviors (O)?

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