logging in or signing up Mod-3 Acute Coronary Syndromes 12 LEAD kwidmeier Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 110 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: July 15, 2011 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript MODULE 3: MODULE 3 Acute Coronary Syndromes Part 1Acute Coronary Syndromes: Acute Coronary Syndromes Definition: Sudden ischemic disorders of the heart Include unstable angina and acute myocardial infarction Represent a continuum of a similar disease processAcute Coronary Syndromes: Acute Coronary Syndromes Acute Coronary Syndromes ACS Unstable Angina USA Non-Q Wave Infarct NQMI Q Wave Infarct QMIAcute Coronary Syndromes: Acute Coronary Syndromes Unstable angina (USA) Non-Q wave MI (NQMI) Q wave MI (QMI)Acute Coronary Syndromes: Acute Coronary Syndromes All have sudden ischemia Can not be differentiated in the first hours All have the same initiating eventsInitiating Events: Initiating Events Plaque rupture Thrombus formation VasoconstrictionPlaque Rupture: Lumen Plaque Rupture Lipid Core Fibrous Cap Stable Vulnerable Lumen Lipid Core Fibrous CapPlaque Rupture: Plaque Rupture Lipid Core Fibrous Cap LumenThrombus Formation: Thrombus Formation Lipid Core Fibrous Cap Platelets AdhereThrombus Formation: Thrombus Formation Platelet Aggregation Lipid CoreThrombus Formation: Thrombus Formation Platelet Aggregation Lipid CoreThrombus Formation: Thrombus Formation Platelet Aggregation Lipid Core FibrinVasoconstriction: VasoconstrictionWill Infarct Occur?: Will Infarct Occur? Tissue Death? Plaque Rupture Thrombus Formation Coronary Vasoconstriction Collateral Circulation Myocardial Oxygen DemandThe Three I’s: The Three I’s Ischemia lack of oxygenation ST depression or T inversion Injury prolonged ischemia ST elevation Infarct death of tissue may or may not show in Q waveSlide 16: Epicardial Coronary Artery Lateral Wall of LV Positive Electrode Septum Left Ventricular Cavity Interior Wall of LV Well Perfused MyocardiumNormal ECG: Normal ECGSlide 18: Epicardial Coronary Artery Lateral Wall of LV Positive Electrode Septum Left Ventricular Cavity Interior Wall of LV IschemiaIschemia: Ischemia Inadequate oxygen to tissue Subendocardial Represented by ST depression or T inversion May or may not result in infarctST depression: ST depressionSlide 21: Thrombus Ischemia InjuryInjury: Injury Prolonged ischemia Transmural Represented by ST elevation Usually results in infarctST elevation: ST elevationInfarct: Infarct Death of tissue Represented by Q wave Not all infarcts develop Q wavesSlide 25: Infarcted Area Electrically Silent Depolarization Many infarcts do not develop Q waves InfarctionQ Waves : Q WavesSlide 27: Infarcted Area Electrically Silent Thrombus Depolarization IschemiaSummary: Summary A normal ECG does NOT rule out ACS ST segment depression represents ischemia Possible infarct ST segment elevation is evidence of AMI Q wave MI may follow ST elevation or depressionAcute Coronary Syndromes: Acute Coronary Syndromes Rapid Recognition and Treatment of ACSSmall Group Task: Small Group Task List and rank risk factors Describe symptoms of the last AMI patient attended Describe the symptoms of a friend or relative when they suffered an AMIGoals for Module 3: Goals for Module 3 Rapidly recognize and treat patients with sudden myocardial ischemiaImmediate Evaluation: Immediate Evaluation Story Risk factors ECGClinical Presentations of ACS : Clinical Presentations of ACS Classic anginal chest pain Atypical chest pain Anginal equivalentsClassic Anginal Chest Pain: Classic Anginal Chest Pain Central anterior chest Dull, fullness, pressure, tightness, crushing Radiates to arms, neck, backAtypical Pain: Atypical Pain Musculoskeletal, positional or pleuritic features Often unilateral May be described as sharp or stabbing Includes epigastric discomfort Females often express atypical painAnginal Equivalents: Anginal Equivalents Dyspnea Palpitations Syncope or pre-syncope General weakness DKAAtypical Presentations: Atypical Presentations Often seen in Female Diabetics ElderlyImportant Notation: Important Notation Note EXACT time symptoms began Duration of symptoms may effect therapeutic options and destination decisionsReview Group Activity: Review Group Activity How many had presentations with classic anginal pain? How many had atypical pain? How many were anginal equivalents?Review Group Activity: Review Group Activity How many risk factors did you list? How did you rate them?Consider Risk Factors: Consider Risk Factors Patients with severe or multiple risk factors should be evaluated with a high index of suspicion for acute coronary syndromeRisk Factors of ACS : Risk Factors of ACS Diabetes Smoking Hypertension Age Family history of CAD Obesity Stress SedentaryAge: Age Males over 35 Females over 40 Infarct can occur at any age Increasing age = increasing riskSummary: Summary Unstable angina and acute myocardial infarction are indistinguishable in the first few hours “Atypical” presentations are common Risk factor evaluation helps identify ACS patientsChronic Stable Angina versus ACS: Chronic Stable Angina versus ACS Not chronic stable angina if… New onset Lower exertion threshold Change in pattern of relief New or different associated symptomsGeneral Therapy for ACS: General Therapy for ACS Assessment Expose the chest Story and risks Monitor & 12-lead Vital signs & Sa0 2 Lab draw/cardiac markers Treatment Oxygen IV access Aspirin NTG MorphineGeneral Therapy for ACS: General Therapy for ACS Assessment and therapy occur simultaneously Findings may alter therapeutic pathExpose the Chest: Expose the Chest Expose the chest immediately Avoids delays in obtaining ECG Prevents entanglement of IV lines, monitor wires, etc. Use reasonable judgement Have gowns availableOxygen: Oxygen 4 lpm nasal cannula if respiratory rate normal and Sa0 2 >95 High flow mask if hypoxia or tachypnea are evident or suspected Advanced airway care for continued or severe hypoxiaVital Signs: Vital Signs Respiratory rate and effort Pulse rate, rhythm, force Blood pressure in both arms, manual then automatic Sa0 2 monitor Cardiac monitor and 12-lead ECG12-Lead ECG: 12-Lead ECG Obtain and transmit with the first set of vital signs Repeat with each set of vital signs Repeat as often as necessaryIV Access: IV Access Adequate line in a suitable vein Draw initial blood as indicated Point of care cardiac markers Blood glucoseAspirin: Aspirin 160-325 mg - chew or swallow Only absolute contraindication is known hypersensitivity to ASA Issues: Asthma patients may have been told to avoid ASA Patients on anti-coagulants Taken ASA already todayNitroglycerin: Nitroglycerin Dilates conduit arteries Antagonizes vasospasm Improves collateral circulation Inhibits venous return Reduces intramyocardial wall tensionNitroglycerin: Nitroglycerin 0.4mg sublingual Repeat every five minutes Contraindications include; Hypotension Viagra within 24 hoursNTG Precautions: NTG Precautions Avoid hypotension Limit systolic drop Don’t use NTG as an analgesic Watch for RVIMorphine: Morphine 2 - 4mg every 5 minutes PRN May require several doses for adequate relief of pain Decreases myocardial oxygen requirements Watch for respiratory depression and hypotensionGeneral Therapy for ACS: General Therapy for ACS Outcomes to general therapy equal reperfusion therapy Some components are time dependent Monitor compliance and outcomes via quality assurance programModule 3: Case 1 : Module 3: Case 1 48 year old male Dull central CP 2/10, began at rest Pale and wet Overweight, smoker Vital signs: RR 18, P 80, BP 180/110, Sa0 2 94% on room airModule 3: Case 1: Module 3: Case 1Module 3: Case 1: Module 3: Case 1 Story Risk factors ECG TreatmentModule 3: Case 2: Module 3: Case 2 68 year old female Sudden onset of anxiety and restlessness, States she “can’t catch her breath” Denies chest pain or other discomfort History of IDDM and hypertension RR 22, P 110, BP 190/90, Sa0 2 88% on NC at 4 lpm.Module 3, Case 2: Module 3, Case 2Module 3: Case 2: Module 3: Case 2 Story Risk factors ECG TreatmentLab for Module 3: Lab for Module 3 Study each ECG Fill in the blanks Provide your impression Examine the case studies Discuss the case You do not have the permission to view this presentation. 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Mod-3 Acute Coronary Syndromes 12 LEAD kwidmeier Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 110 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: July 15, 2011 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... Premium member Presentation Transcript MODULE 3: MODULE 3 Acute Coronary Syndromes Part 1Acute Coronary Syndromes: Acute Coronary Syndromes Definition: Sudden ischemic disorders of the heart Include unstable angina and acute myocardial infarction Represent a continuum of a similar disease processAcute Coronary Syndromes: Acute Coronary Syndromes Acute Coronary Syndromes ACS Unstable Angina USA Non-Q Wave Infarct NQMI Q Wave Infarct QMIAcute Coronary Syndromes: Acute Coronary Syndromes Unstable angina (USA) Non-Q wave MI (NQMI) Q wave MI (QMI)Acute Coronary Syndromes: Acute Coronary Syndromes All have sudden ischemia Can not be differentiated in the first hours All have the same initiating eventsInitiating Events: Initiating Events Plaque rupture Thrombus formation VasoconstrictionPlaque Rupture: Lumen Plaque Rupture Lipid Core Fibrous Cap Stable Vulnerable Lumen Lipid Core Fibrous CapPlaque Rupture: Plaque Rupture Lipid Core Fibrous Cap LumenThrombus Formation: Thrombus Formation Lipid Core Fibrous Cap Platelets AdhereThrombus Formation: Thrombus Formation Platelet Aggregation Lipid CoreThrombus Formation: Thrombus Formation Platelet Aggregation Lipid CoreThrombus Formation: Thrombus Formation Platelet Aggregation Lipid Core FibrinVasoconstriction: VasoconstrictionWill Infarct Occur?: Will Infarct Occur? Tissue Death? Plaque Rupture Thrombus Formation Coronary Vasoconstriction Collateral Circulation Myocardial Oxygen DemandThe Three I’s: The Three I’s Ischemia lack of oxygenation ST depression or T inversion Injury prolonged ischemia ST elevation Infarct death of tissue may or may not show in Q waveSlide 16: Epicardial Coronary Artery Lateral Wall of LV Positive Electrode Septum Left Ventricular Cavity Interior Wall of LV Well Perfused MyocardiumNormal ECG: Normal ECGSlide 18: Epicardial Coronary Artery Lateral Wall of LV Positive Electrode Septum Left Ventricular Cavity Interior Wall of LV IschemiaIschemia: Ischemia Inadequate oxygen to tissue Subendocardial Represented by ST depression or T inversion May or may not result in infarctST depression: ST depressionSlide 21: Thrombus Ischemia InjuryInjury: Injury Prolonged ischemia Transmural Represented by ST elevation Usually results in infarctST elevation: ST elevationInfarct: Infarct Death of tissue Represented by Q wave Not all infarcts develop Q wavesSlide 25: Infarcted Area Electrically Silent Depolarization Many infarcts do not develop Q waves InfarctionQ Waves : Q WavesSlide 27: Infarcted Area Electrically Silent Thrombus Depolarization IschemiaSummary: Summary A normal ECG does NOT rule out ACS ST segment depression represents ischemia Possible infarct ST segment elevation is evidence of AMI Q wave MI may follow ST elevation or depressionAcute Coronary Syndromes: Acute Coronary Syndromes Rapid Recognition and Treatment of ACSSmall Group Task: Small Group Task List and rank risk factors Describe symptoms of the last AMI patient attended Describe the symptoms of a friend or relative when they suffered an AMIGoals for Module 3: Goals for Module 3 Rapidly recognize and treat patients with sudden myocardial ischemiaImmediate Evaluation: Immediate Evaluation Story Risk factors ECGClinical Presentations of ACS : Clinical Presentations of ACS Classic anginal chest pain Atypical chest pain Anginal equivalentsClassic Anginal Chest Pain: Classic Anginal Chest Pain Central anterior chest Dull, fullness, pressure, tightness, crushing Radiates to arms, neck, backAtypical Pain: Atypical Pain Musculoskeletal, positional or pleuritic features Often unilateral May be described as sharp or stabbing Includes epigastric discomfort Females often express atypical painAnginal Equivalents: Anginal Equivalents Dyspnea Palpitations Syncope or pre-syncope General weakness DKAAtypical Presentations: Atypical Presentations Often seen in Female Diabetics ElderlyImportant Notation: Important Notation Note EXACT time symptoms began Duration of symptoms may effect therapeutic options and destination decisionsReview Group Activity: Review Group Activity How many had presentations with classic anginal pain? How many had atypical pain? How many were anginal equivalents?Review Group Activity: Review Group Activity How many risk factors did you list? How did you rate them?Consider Risk Factors: Consider Risk Factors Patients with severe or multiple risk factors should be evaluated with a high index of suspicion for acute coronary syndromeRisk Factors of ACS : Risk Factors of ACS Diabetes Smoking Hypertension Age Family history of CAD Obesity Stress SedentaryAge: Age Males over 35 Females over 40 Infarct can occur at any age Increasing age = increasing riskSummary: Summary Unstable angina and acute myocardial infarction are indistinguishable in the first few hours “Atypical” presentations are common Risk factor evaluation helps identify ACS patientsChronic Stable Angina versus ACS: Chronic Stable Angina versus ACS Not chronic stable angina if… New onset Lower exertion threshold Change in pattern of relief New or different associated symptomsGeneral Therapy for ACS: General Therapy for ACS Assessment Expose the chest Story and risks Monitor & 12-lead Vital signs & Sa0 2 Lab draw/cardiac markers Treatment Oxygen IV access Aspirin NTG MorphineGeneral Therapy for ACS: General Therapy for ACS Assessment and therapy occur simultaneously Findings may alter therapeutic pathExpose the Chest: Expose the Chest Expose the chest immediately Avoids delays in obtaining ECG Prevents entanglement of IV lines, monitor wires, etc. Use reasonable judgement Have gowns availableOxygen: Oxygen 4 lpm nasal cannula if respiratory rate normal and Sa0 2 >95 High flow mask if hypoxia or tachypnea are evident or suspected Advanced airway care for continued or severe hypoxiaVital Signs: Vital Signs Respiratory rate and effort Pulse rate, rhythm, force Blood pressure in both arms, manual then automatic Sa0 2 monitor Cardiac monitor and 12-lead ECG12-Lead ECG: 12-Lead ECG Obtain and transmit with the first set of vital signs Repeat with each set of vital signs Repeat as often as necessaryIV Access: IV Access Adequate line in a suitable vein Draw initial blood as indicated Point of care cardiac markers Blood glucoseAspirin: Aspirin 160-325 mg - chew or swallow Only absolute contraindication is known hypersensitivity to ASA Issues: Asthma patients may have been told to avoid ASA Patients on anti-coagulants Taken ASA already todayNitroglycerin: Nitroglycerin Dilates conduit arteries Antagonizes vasospasm Improves collateral circulation Inhibits venous return Reduces intramyocardial wall tensionNitroglycerin: Nitroglycerin 0.4mg sublingual Repeat every five minutes Contraindications include; Hypotension Viagra within 24 hoursNTG Precautions: NTG Precautions Avoid hypotension Limit systolic drop Don’t use NTG as an analgesic Watch for RVIMorphine: Morphine 2 - 4mg every 5 minutes PRN May require several doses for adequate relief of pain Decreases myocardial oxygen requirements Watch for respiratory depression and hypotensionGeneral Therapy for ACS: General Therapy for ACS Outcomes to general therapy equal reperfusion therapy Some components are time dependent Monitor compliance and outcomes via quality assurance programModule 3: Case 1 : Module 3: Case 1 48 year old male Dull central CP 2/10, began at rest Pale and wet Overweight, smoker Vital signs: RR 18, P 80, BP 180/110, Sa0 2 94% on room airModule 3: Case 1: Module 3: Case 1Module 3: Case 1: Module 3: Case 1 Story Risk factors ECG TreatmentModule 3: Case 2: Module 3: Case 2 68 year old female Sudden onset of anxiety and restlessness, States she “can’t catch her breath” Denies chest pain or other discomfort History of IDDM and hypertension RR 22, P 110, BP 190/90, Sa0 2 88% on NC at 4 lpm.Module 3, Case 2: Module 3, Case 2Module 3: Case 2: Module 3: Case 2 Story Risk factors ECG TreatmentLab for Module 3: Lab for Module 3 Study each ECG Fill in the blanks Provide your impression Examine the case studies Discuss the case