Diagnosis Of Hepatitus B Virus

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A short ppt presentation for undergraduates to get knowledge about HBV diagnosis.to get Microsoft power point format copy Email (kayani.irfan@gmail.com)

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Diagnosis of Hepatitis B Virus:

Diagnosis of Hepatitis B Virus Presented By Muhammad Hashim Raza Muhammad Bahader Sher Hafiz Irfan shabbir Kayani Shamas Pervaiz Presented To Sir Zia-ur-Rehman Farooqi CMLT, National Institute of Health Islamabad Pakistan ( kayani.irfan@gmail.com )

Introduction::

Introduction: HBV is an enveloped double stranded virus recognized as the major cause of blood transmitted hepatitis together with HCV. Infection with HBV induces a spectrum of Clinical manifestation ranging from mild inappearent disease to fullminant hepatitis, severe chronic liver disease which can in some cases led to cirrhosis and carcinoma of liver. Several diagnostic test are used for screening, clinical diagnosis and management of disease.

A test to determine whether you can easily pass HBV to others. :

A test to determine whether you can easily pass HBV to others . The hepatitis B surface antigen (HBsAg) test looks for hepatitis B surface antigen — part of the outer surface of the virus. Testing positive for this antigen means you have an active hepatitis B infection and can easily pass the virus to others. A negative test means you're probably not currently infected. The HBsAg test is carried out using techniques, Immuno Chromatographic Technique Enzyme Linked Immuno Sorbent Assay

A test to determine whether you're immune to HBV. :

A test to determine whether you're immune to HBV. The antibody to hepatitis B surface antigen (anti-HBs) test determines if you have antibodies to HBV. Having antibodies can be due to a prior HBV infection from which you've recovered. Or, it can mean you may already have been vaccinated. In either case, a positive anti-HBs test means you can't infect others or become infected yourself because you're protected by the vaccine or your own natural immunity. Enzyme Linked Immuno Sorbent Assay is used to detect antibodies to HBV.

A test to determine whether you have had or currently have a hepatitis B infection.:

A test to determine whether you have had or currently have a hepatitis B infection. The antibody to hepatitis B core antigen (anti- HBc ) test identifies people who have an HBV infection. If you test positive for hepatitis B core antibodies, you may have a chronic infection that you can transmit to others. A positive result may also mean you're recovering from an acute infection or have a slight immunity to HBV that can't otherwise be detected. How this test is interpreted often depends on the results of the other two tests. Enzyme Linked Immuno Sorbent Assay is used to measure hepatitis B core antigen.

A test to determine how likely you are to spread HBV to others:

A test to determine how likely you are to spread HBV to others The E antigen blood test looks for the presence of a protein secreted by HBV-infected cells. A positive result means you have high levels of the virus in your blood and can easily infect others. If the test is negative, you have lower blood levels of HBV and are less likely to spread the infection. Enzyme Linked Immuno Sorbent Assay is used to measure hepatitis E antigen.

A test to determine how much HBV DNA is in your blood:

A test to determine how much HBV DNA is in your blood The hepatitis B DNA test detects parts of HBV DNA in blood, indicating how much virus is present (viral load). Assessing your viral load can help monitor how well antiviral therapy is working. HBV DNA test is carried out using a technique known as Polymerase Chain Reaction.

Tests to measure liver function:

Tests to measure liver function Liver function tests may gauge the amount of damage that has occurred in your liver cells. The term "liver function tests" can be misleading, because not all of these tests actually measure liver function. Some tests, such as albumin and bilirubin , do. These liver function tests measure how well the liver is producing the protein albumin and clearing a blood waste product, bilirubin . Other tests commonly done, but not true "liver function" tests, measure enzymes that liver cells release in response to damage or disease.

PowerPoint Presentation:

Copyright © irfan shabbir kayani(kayani.irfan @gmail.com) Time sequence of serologic indicators of acute hepatitis B

PowerPoint Presentation:

Marker Acute infection Chronic infection Past infection HBsAg + + - HBeAg + early, then- ± - anti-HBs - - + anti-HBcIgM + - - anti-HBcIgG + + + anti-HBe - early, then+ ± + HBV DNA + early, then- ± - ALT increased (marked) increased (mild–moderate) normal

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