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RECTUS MUSCLE OF FROG By. Jyotirmoy Das Choudhury M.Pharm 1 st semester Phamacology Under the Guidance of Mr. G. Panigrahy . Lecturer Pharmacology Department


CONTENTS Definition of Rectus muscle. Location of Rectus muscle. Blood supply to Rectus muscle. Receptors present in Rectus muscle. Functions of Rectus muscle. Frog’s Rectus Abdominis Muscle Preparation. Pharmacological importance. Conclusion. References. 2

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Rectus abdominis muscle is a paired muscle running vertically on each side of the anterior wall. 4


Location The rectus abdominis is a long flat muscle, which extends along the whole length of the front of the abdomen. It extends from pubic symphysis to the xiphistretum & lower costal cartilages (5-7) superiorly. 5

Blood Supply:

Blood Supply It has several sources for arterial blood supply. Inferior epigastric artery & veins. Superior epigastric artery. Numerous small segmental contribution coming from lower inter costal arteries. 6


Receptors The rectus abdominis muscle of frog mainly rich of Nicotinic receptor. They mainly respond to the acetyicholine released from motor neuron terminal. 7


Functions It is an important postural muscle. Helps to flexing lumbar spine. Plays an important role in breathing It helps to keep internal organ intact. 8

Frog’s Rectus Muscle Preparation. :

Frog’s Rectus Muscle Preparation. 9

Use in Pharmacology:

Use in Pharmacology The Rectus Muscle of frog is used in the screening of parasympatholytic agents. It is also useful for bioassay of Acetylcholine. Bioassay of D- Tubocurarine . 10

Ringer Solution:

Ringer Solution 11 Components Amount(gm) Nacl 6.5 Kcl 0.29 Cacl 2 0.24 NaHCo 3 0.4 Glucose 1.5 Distilled water Upto 2000ml


Conclusion Rectus abdominis muscle of frog has various importance in pharmacology. It is a perfect in vitro model. It helps to maintain various physiological condition & posture. 12

References :

References Wikipedia. “Pharmacology- Principle & Method of Bioassay.” By. Prof. Ramesh K. Goyel . L. M. College of Pharmacy, Ahmedabad . Page- 12, 17,18. Screening Methods In Pharmacology. By. R. A. Turner. Page- 140-141. 13

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