GREEN CHEMISTRY: ITS APPLICATION IN NANOMEDICINE

Views:
 
     
 

Presentation Description

Green synthesis of gold and silver nanoparticles

Comments

Presentation Transcript

GREEN CHEMISTRY: ITS APPLICATIONS IN NANOMEDICINE Guide DR. AMRISH CHANDRA: 

GREEN CHEMISTRY: ITS APPLICATIONS IN NANOMEDICINE Guide DR. AMRISH CHANDRA PRESENTED BY : JAGJIT SINGH M.Pharm PHARM. BIOTECHNOLOGY SEM - III rd

CONTENT: 

CONTENT INTRODUCTION: WHAT IS GREEN CHEMISTRY? TWELVE PRINCIPLE OF GREEN CHEMISTRY ENVIRONMENT PROTECTION AGENCY USA WHY TO GO GREEN? GREEN CHEMISTRY IN NANOTECHNOLOGY GREEN CHEMISTRY APPLICATION IN NANOMEDICINE GREEN SYNTHESIS OF NANOMEDICINES FROM PLANTS FROM MICROORGANISM 8. MECHANISM OF NANOPARTICLE SYNTHESIS CHARACTERISATION OF NANOPARTICLES CURRENT SCENARIO CONCLUSION 13. REFERENCES

INTRODUCTION: 

INTRODUCTION Green chemistry - also known as sustainable chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances.( Paul T Anatas ) It is better to prevent waste than to clear it up afterward % Atom economy is the new % yield of product The drive towards the perfect synthesis pathway Sustainable by design Environmentally friendly and economically sound.

TWELVE PRINCIPLES OF GREEN CHEMISTRY: 

TWELVE PRINCIPLES OF GREEN CHEMISTRY Prevention Atom Economy Less Hazardous Chemical Synthesis Designing Safer Chemical Safer Solvents and Auxiliaries Design for Energy Efficiency Use of Renewable Feedstock Reduce derivatives Catalysis Design for degradation Real-time analysis for pollution prevention Inherently safer chemistry for Accident Prevention

ENVIRONMENT PROTECTION AGENCY USA: 

ENVIRONMENT PROTECTION AGENCY USA The U.S. Environmental Protection Agency ( EPA or sometimes USEPA ) is an agency of the federal government of the United State charged with protecting human health and the environment. In 1990 , The Pollution Prevention Act of 1990 created a national policy to prevent or reduce pollution at its source whenever possible . In 1993, EPA program officially adopted the name “U.S. Green Chemistry Program ”

WHY TO GO GREEN ? Ref: James H. Clark,(1999), Green chemistry: challenge and prospectives, Green Chemistry: 

WHY TO GO GREEN ? Ref: James H. Clark,(1999), Green chemistry: challenge and prospectives , Green Chemistry

APPLYING GREEN PRINCIPLES TO NANOTECHNOLOGY: 

APPLYING GREEN PRINCIPLES TO NANOTECHNOLOGY GREEN CHEMISTRY PRINCIPLES P4. Designing Safer Chemical P12. Inherently safer chemistry for Accident Prevention P7. Use of Renewable Feedstock P10. Design for degradation P1.Prevent Waste P5. Safer Solvents and Auxiliaries P8. Reduce derivatives GREEN NANOTECHNOLOGY Design of safer nanomaterials (P4,P12) Design for reduce environment impact (P7,P10) Design for waste reduction (P1,P5,P8)

PowerPoint Presentation: 

P3. Less hazardous chemical synthesis P5. Safer Solvents and Auxiliaries P7. Use of Renewable Feedstock P12. Inherently safer chemistry for Accident Prevention P2. Atom economy P5. Safer Solvents and Auxiliaries P9. Catalysis P11. Real-time analysis for pollution prevention P6. Design for energy efficiency P9. Catalysis P11. Real-time analysis for pollution prevention Design for process safety (P3,P5,P7,P12) Design for materials efficiency (P2,P5,P9,P11) Design for energy efficiency (P6,P9,P11)

GREEN TECHNOLOGY: 

GREEN TECHNOLOGY GREEN SYNTHESIS Renewable Feedstock Catalysis ToxCast & ToxPi Solventless Reactions Innovative Engineering Alternative Solvents Process Intensification

NANOMATERIALS USED AS NANOMEDICINES WITH GREEN SYNTHESIS: 

NANOMATERIALS USED AS NANOMEDICINES WITH GREEN SYNTHESIS NANOMATERIAL CLINICAL USE GREEN SYNTHESIS GOLD Cancer therapy, Diagnosis From plant extracts, From Bacteria Silver Anti-microbial activity Almond leaves, Tannic acid Iron oxide MRI contrast, Diagnostic From tea leaf extract, Bacteria Zinc oxide Anti -bacterial activity From plant extracts Carbon Nanotubes Toxicology studies, Cancer Using Camphor, Biodiesel (plant)

S0ME IMPORTANT MANUFACTURING METHODS : 

S0ME IMPORTANT MANUFACTURING METHODS BOTTOM UP APPROACH TOP DOWN APPROACH NANOPARTICLES SYNTHESIS 1.ETCHING 2.MECHANICAL MILLING GREEN SYNTHESIS 1.MICRO-ORGANISM 2.PLANT EXTRACT BACTERIA FUNGI

GREEN SYNTHESIS OF SOME NANOMEDICINES GOLD NANOPARTICLES : 

GREEN SYNTHESIS OF SOME NANOMEDICINES GOLD NANOPARTICLES TEA LEAF EMBLICA OFFICINALE EDIBLE MUSHROOM TAMARINDUS INDICA FROM PLANT EXTRACT

SILVER NANOPARTICLES: 

SILVER NANOPARTICLES ALMOND LEAVES ALOE VERA HONEY TANNIC ACID

Ref:© The Royal Society of Chemistry 2011(Green Chemistry) : 

Ref: © The Royal Society of Chemistry 2011(Green Chemistry)

GREEN SYNTHESIS FROM MICROORGANISMS Ref:Rev Environ Sci Biotechnology(2010),publish online on Feb 2010: 

GREEN SYNTHESIS FROM MICROORGANISMS Ref: Rev Environ Sci Biotechnology(2010),publish online on Feb 2010

MECHANISM OF NPs SYNTHESIS (MICROORGANISM) Ref:Rev Environ Sci Biotechnology(2010),publish online on Feb 2010 : 

MECHANISM OF NPs SYNTHESIS (MICROORGANISM) Ref: Rev Environ Sci Biotechnology(2010),publish online on Feb 2010

CHARACTERISATION OF NANOMATERIALS Ref: http://www.e-journals.net/: 

CHARACTERISATION OF NANOMATERIALS Ref: http://www.e-journals.net/ TEM(TRANSMISSION ELECTRON MICROSCOPE)I

Ref:http://www.e-journals.net: 

Ref:http :// www.e-journals.net UV-ABSORPTIOPN(SILVER NANOPARTICLES)

CURRENT SCENARIO: 

CURRENT SCENARIO

CONCLUSION: 

CONCLUSION

REFERENCES: 

REFERENCES 1. Paul T. Anastas and Mary M. Kirchhoff,(2002), Origin and current status, and future challenges of green chemistry, Accounts of Chemical Research, 35, 686-694. 2. www.epa.gov 3. Betty Y.S. Kim, James T. Rutka and Warren C.W. Chan, (2010), Nanomedicine , The New England journal of medicine, 363, 2434-2443. 4. www.epa.gov/nanoscience 5. www.epa.gov/research 6. K.L. Dreher , (2004), Health and environment impact of nanotechnology, Toxicol Sci., 11, 3-5. 7. P. Tundo and P.T. Anastus , (1999), Green Chemistry: challenging prospectives , Oxford Science. 8. Matthew A. Albrecht, Cameron W. Evans and Colin L. Raston , (2006), Green chemistry and the health implications of nanoparticles . The Royal Society of Chemistry , 8, 417–432.

PowerPoint Presentation: 

9. James H. Clark,(1999), Green chemistry: challenge and prospectives , Green Chemistry. 10. Virender K. Sharma, Ria A. Yngard , Yekaterina Lin, (2009), Silver nanoparticles:Green synthesis and their antimicrobial activities, Advances in Colloid and Interface Science, 145, 83–96. 11.http://www.nanotechproject.org/file_download/files/Hutchison.pdf 12. Poovathinthodiyil Raveendran , Jie Fua and Scott L. Wallen ,(2003), J. Am. Chem. Soc.,125, 13940-13941. 13. http://www.wired.com/wired/archive/8.04 14. http://www.rsc.org/publishing/chemscience/volume/2008/nano-formsofcarbon.asp 15 S.Ozkar and R. G. Finke, (2005), J. Am. Chem. Soc., 127, 4800-4808 16. C. B Wang and W. X. Zhang, (1997), Synthesizing nanoscale iron particles for rapid and complete dechlorination of TCE and PCBs, Environment Science Technology, 31, 2145-2156 .

THANK YOU: 

THANK YOU