logging in or signing up DRUG METABOLISM jagadeeshbabu712 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 165 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: January 25, 2012 This Presentation is Public Favorites: 1 Presentation Description This ppt will give the information about how the drug is metabolized in our body. Post ur comments on this ppt. Thank u... Comments Posting comment... Premium member Presentation Transcript DRUG METABOLISM: DRUG METABOLISMOVER VEIW: INTRODUCTION INDETAIL ABOUT D.M FACTORS EFFECT D.M IMPORTANCE CONCLUSION : OVER VEIW : INTRODUCTION INDETAIL ABOUT D.M FACTORS EFFECT D.M IMPORTANCE CONCLUSIONINTRODUCTION:: DEFINITION NEED FOR DRUG METABOLISM DRUG METABOLYSING ORGANS LIVER INTRODUCTION :LIVER:: LIVER : ACTIVATE DRUGS INACTIVATE DRUGS CONVET DRUGS TO SOLUBLE FORM SO THAT IT CAN EASILY EXCRETE THROUGH KIDNEYSOUT LINE OF DRUG METABOLISM: OUT LINE OF DRUG METABOLISMDRUG METABOLISM INDETAIL: DRUG METABOLISM INDETAIL DRUG METABOLISM INCLUDES PHASE I REACTIONS PHASE II REACTIONSPHASE I REACTIONS: PHASE I REACTIONS OXIDATION REDUCTION HYDROLYSIS P450 SYSTEM: P450 SYSTEM BREAK DOWN DRUGS INTO SMALLER MOLECULES GROUP OF 12 CLOSELY RELATED ENZYME FAMILIES IN THE LIVER CYP1,CYP2 & CYP3 METABOLIZE DRUGSOXIDATION-REDUCTION CYCLE : OXIDATION-REDUCTION CYCLEPHASE II REACTIONS: PHASE II REACTIONS Methylation Sulphation Acetylation GlucuronidationIMPORTANCE: IMPORTANCE Drug metabolism is very useful in detecting the metabolism of drugs in clinical trials. It is used for knowing drug-drug interactions Due to inactivation of the drug it can reduces drug toxicity.CONCLUSION: CONCLUSION By knowing about the drug metabolism we can easily say that knowing about it is so important for the people who are studying about “DRUGS”.THANK YOU: THANK YOU B.JAGADEESH You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
DRUG METABOLISM jagadeeshbabu712 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 165 Category: Education License: All Rights Reserved Like it (0) Dislike it (0) Added: January 25, 2012 This Presentation is Public Favorites: 1 Presentation Description This ppt will give the information about how the drug is metabolized in our body. Post ur comments on this ppt. Thank u... Comments Posting comment... Premium member Presentation Transcript DRUG METABOLISM: DRUG METABOLISMOVER VEIW: INTRODUCTION INDETAIL ABOUT D.M FACTORS EFFECT D.M IMPORTANCE CONCLUSION : OVER VEIW : INTRODUCTION INDETAIL ABOUT D.M FACTORS EFFECT D.M IMPORTANCE CONCLUSIONINTRODUCTION:: DEFINITION NEED FOR DRUG METABOLISM DRUG METABOLYSING ORGANS LIVER INTRODUCTION :LIVER:: LIVER : ACTIVATE DRUGS INACTIVATE DRUGS CONVET DRUGS TO SOLUBLE FORM SO THAT IT CAN EASILY EXCRETE THROUGH KIDNEYSOUT LINE OF DRUG METABOLISM: OUT LINE OF DRUG METABOLISMDRUG METABOLISM INDETAIL: DRUG METABOLISM INDETAIL DRUG METABOLISM INCLUDES PHASE I REACTIONS PHASE II REACTIONSPHASE I REACTIONS: PHASE I REACTIONS OXIDATION REDUCTION HYDROLYSIS P450 SYSTEM: P450 SYSTEM BREAK DOWN DRUGS INTO SMALLER MOLECULES GROUP OF 12 CLOSELY RELATED ENZYME FAMILIES IN THE LIVER CYP1,CYP2 & CYP3 METABOLIZE DRUGSOXIDATION-REDUCTION CYCLE : OXIDATION-REDUCTION CYCLEPHASE II REACTIONS: PHASE II REACTIONS Methylation Sulphation Acetylation GlucuronidationIMPORTANCE: IMPORTANCE Drug metabolism is very useful in detecting the metabolism of drugs in clinical trials. It is used for knowing drug-drug interactions Due to inactivation of the drug it can reduces drug toxicity.CONCLUSION: CONCLUSION By knowing about the drug metabolism we can easily say that knowing about it is so important for the people who are studying about “DRUGS”.THANK YOU: THANK YOU B.JAGADEESH