Introduction to Hemoglobin Lab

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Presentation Description

This introduction to the Biologylabsonline hemoglobin lab introduces you to the nature of the human genetic code and how it relates to variations in the beta hemoglobin protein

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Presentation Transcript

Protein SynthesisCentral Dogma : 

Protein SynthesisCentral Dogma

The code : 

The code

The mistake in the gene : 

The mistake in the gene DNA triplet codes 506-510 involved, involves amino acids 506-510 of the 1480 total in the protein TAG TAG AAA CCA CAA (gene) AUC AUC UUU GGU GUU (mRNA) Ile - Ile - Phe - Gly - Val (protein) TAG TAA CCA CAA (defective gene) Ile code preserved (wobble), Phe is lost

Protein Electrophoresis : 

Protein Electrophoresis migrate through gel based on charge Changing the amino acid might change the charge

The mistake : 

The mistake a glutamate is replaced with a valine at position 6