Thyrotoxicosis

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scintigraphic manifestations of Thyrotoxicosis

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Scintigraphic Manifestations of Thyrotoxicosis: 

Scintigraphic Manifestations of Thyrotoxicosis Dr. Ahmed Abdo Harwn د. أحمد عبده عبدالله هارون Nuclear Medicine Consultant 1 December 2011 1 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

LEARNING OBJECTIVES: 

LEARNING OBJECTIVES 1 December 2011 2 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

Thyroid physiology 1 December 2011 3 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

Thyroid physiology 1 December 2011 4 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

Thyroid physiology 1 December 2011 5 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

Iodine metabolism 1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 6

Deficiency:: 

Deficiency: 1 December 2011 7 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Daily allownce: 

Daily allownce 1 December 2011 8 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 9

Iodine Sources: 

Iodine Sources 1 December 2011 10 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Iodide pools:: 

Iodide pools: 1 December 2011 11 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Excess amount of Iodide in Normal person.: 

Excess amount of Iodide in Normal person. 1 December 2011 12 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Excess Iodide in abnormal situation : 

Excess Iodide in abnormal situation 1 December 2011 13 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Thyroid Hormone synthesis: 

Thyroid Hormone synthesis 1 December 2011 14 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Thyroid Hormone synthesis: 

Organification (Oxidative iodination) & iodination MIT or DIT Stimulated by TSH Inhibited by methimazole , PTU, lithium, excess iodide. Thyroid Hormone synthesis 1 December 2011 15 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Thyroid Hormone synthesis: 

Coupling of iodo - tyrosine Thyroid Hormone synthesis 1 December 2011 16 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Thyroid Hormone synthesis: 

Release. (last come , first served) Thyroid Hormone synthesis 1 December 2011 17 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Thyroid hormone action: 

Thyroid hormone action 1 December 2011 18 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 19 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn Signs and symptoms

PowerPoint Presentation: 

1 December 2011 20 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Classification of thyrotoxicosis: 

Classification of thyrotoxicosis 1 December 2011 21 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Graves Disease (diffuse toxic goiter): 

Graves Disease (diffuse toxic goiter ) 1 December 2011 22 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Graves Disease (diffuse toxic goiter): 

Graves Disease (diffuse toxic goiter) 1 December 2011 23 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Graves Disease (diffuse toxic goiter): 

Graves Disease (diffuse toxic goiter ) 1 December 2011 24 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Therapy: 

Therapy 1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 25

Marine-Lenhart Syndrome: 

Marine- Lenhart Syndrome 1 December 2011 26 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Marine-Lenhart Syndrome: 

Marine- Lenhart Syndrome 1 December 2011 27 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Toxic Autonomous Nodule (toxic adenoma): 

Toxic Autonomous Nodule (toxic adenoma) 1 December 2011 28 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Toxic Autonomous Nodule (toxic adenoma): 

Toxic Autonomous Nodule (toxic adenoma) 1 December 2011 29 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Toxic Multinodular Goiter: 

Toxic Multinodular Goiter 1 December 2011 30 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Toxic Multinodular Goiter: 

Toxic Multinodular Goiter 1 December 2011 31 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Toxic Multinodular Goiter: 

Toxic Multinodular Goiter 1 December 2011 32 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Subacute thyroiditis: 

Subacute thyroiditis 1 December 2011 33 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Subacute thyroiditis: 

Subacute thyroiditis 1 December 2011 34 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Subacute thyroiditis: 

Subacute thyroiditis 1 December 2011 35 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Silent Thyroiditis: 

Silent Thyroiditis 1 December 2011 36 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Silent Thyroiditis: 

Silent Thyroiditis 1 December 2011 37 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Silent Thyroiditis: 

1 December 2011 38 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn Silent Thyroiditis

Silent Thyroiditis: 

1 December 2011 39 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn Silent Thyroiditis

Silent Thyroiditis: 

1 December 2011 40 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn Silent Thyroiditis

Postpartum thyroiditis: 

Postpartum thyroiditis 1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 41

Iodine-induced Hyperthyroidism (Jod-Basedow phenomenon). : 

Iodine-induced Hyperthyroidism ( Jod-Basedow phenomenon). 1 December 2011 42 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Iodine-induced Hyperthyroidism (Jod-Basedow phenomenon). : 

Iodine-induced Hyperthyroidism ( Jod-Basedow phenomenon). 1 December 2011 43 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 44 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Factitious Hyperthyroidism: 

Factitious Hyperthyroidism 1 December 2011 45 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 46 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 47 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 48

Metastatic Thyroid Cancer: 

Metastatic Thyroid Cancer 1 December 2011 49 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

PowerPoint Presentation: 

1 December 2011 50 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Struma Ovarii: 

Struma Ovarii 1 December 2011 51 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Struma Ovarii: 

Struma Ovarii 1 December 2011 52 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Struma Ovarii: 

Struma Ovarii 1 December 2011 53 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

TSH-induced Thyrotoxicosis: 

TSH-induced Thyrotoxicosis 1 December 2011 54 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn

Conclusions: 

Conclusions 1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 55

References: 

References 1 December 2011 Scintigraphic manifistations of thyrotoxicosis – Dr.Ahmed Harwn 56