post partum cerebellar infarction

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PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

A case of post partum cerebellar infarction : 

A case of post partum cerebellar infarction 29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

A case of post partum cerebellar infarction : 

A case of post partum cerebellar infarction 29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

A case of post partum cerebellar infarction: 

A case of post partum cerebellar infarction 29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

Thrombophilia is a visitor pregnancy invites it earlier: 

Thrombophilia is a visitor pregnancy invites it earlier 29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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? How much is inherited thrombophilia common among general population 29/07/2010 thrombophilia and pregnancy

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Prevalence in General Population, % Condition 3-7% Factor V Leiden 1-3% Prothrombin 20210A 0.02-.0.05 Protein C 0.01-1 Protein S 0.04-0.05 Antithrombin III 7-11% 29/07/2010 thrombophilia and pregnancy

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What is your advise about her future pregnancy ? What is your advise to a similar case but with out living children? What is the best contraceptive in this case? 29/07/2010 thrombophilia and pregnancy

PowerPoint Presentation: 

29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

Follow up : 

Follow up 29/07/2010 thrombophilia and pregnancy

LABOUR: 

LABOUR At 37 wk . PROM occurred, so I stopped heparin and aspirin and CS was done after 12 hours. The fetus weighed 2700 grams with good apgar score at 1 and 5 minutes .the placenta was of average wt. With multiple infarcts . 12 hours post partum heparinisation was resumed in a prophylactic dose ) 5000u/12h) sc. With warfarin , after 10 days heparin was stopped and warfarin (5 mg/day ) continued . corticosteroid had been gradually withdrown over three weeks . 29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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Sapporo in 1998 Sapporo criteria 29/07/2010 thrombophilia and pregnancy

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Antiphospholipid antibody committee meeting in Sapporo, Japan, in the end of 1998, published clinical criteria in Arthritis and Rheumatism journal in 1999. Sapporo criteria

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clinical criteria 29/07/2010 thrombophilia and pregnancy And ,or

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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Type of heparin MVP* Proteinuria Bl.P Termination (wk) Onset PE (wk) FH* >2cm decreased decreased 36 33 Case 1 UFH* <2cm ▲ unchanged decreased 35 33 Case 2 FH >2cm increased unchanged 31+3d 31 Case 3 UFH <2cm ▲ unchanged decreased 36 34 Case 4 FH >2cm increased unchanged 32+3d 32 Case 5 UFH >2cm increased unchanged 33+3d 33 Case 6 FH <2cm ▲ unchanged decreased 35 30 Case 7 FH <2cm ▲ unchanged decreased 35 33 Case 8 UFH >2cm decreased decreased 34 28 Case 9 UFH <2cm ▲ decreased decreased 36 32 Case 10 UFH >2cm increased unchanged 30+3d 30 Case 11 UFH >2cm increased unchanged 33+2d 33 Case 12 UFH >2cm decreased decreased 36 33 Case 13 29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

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29/07/2010 thrombophilia and pregnancy

On base of assumption that placental ischemia and vasculopathy is the pathogenomic of preeclampsia , would we get better results using therapeutic dose of heparin ? It is a question for future research. : 

On base of assumption that placental ischemia and vasculopathy is the pathogenomic of preeclampsia , would we get better results using therapeutic dose of heparin ? It is a question for future research. 29/07/2010 thrombophilia and pregnancy

Thank you: 

Thank you 29/07/2010 thrombophilia and pregnancy