Euphoria and Toxicity-Cocaine Effects to the Brain- A Fatal Attraction

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Are dangerous cocaine effects to the brain worth the “high”? The intense pleasure response is hard to resist by as many as two million USA users from the working class to the glamorous. Cocaine, extracted from the leaf of the Erythroxylon coca plant, is a local anesthetic and central nervous system stimulant. Learn more about Forensic Toxicology at www.environmentaldiseases.com

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Euphoria and Toxicity--Cocaine Effects to the Brain: A Fatal Attraction?:

Euphoria and Toxicity--Cocaine Effects to the Brain: A Fatal Attraction?

Are dangerous cocaine effects to the brain worth the “high”?:

Are dangerous cocaine effects to the brain worth the “high”?

Cocaine, extracted from the leaf of the Erythroxylon coca plant, is a local anesthetic and central nervous system stimulant.:

Cocaine, extracted from the leaf of the Erythroxylon coca plant, is a local anesthetic and central nervous system stimulant.

When smoked, injected, inhaled or “snorted” through the nasal passages, cocaine hits the brain within seconds or minutes.:

When smoked, injected, inhaled or “snorted” through the nasal passages, cocaine hits the brain within seconds or minutes.

Cocaine’s nearly instantaneous effect on the brain is twofold: euphoria and toxicity.:

Cocaine’s nearly instantaneous effect on the brain is twofold: euphoria and toxicity.

Neurotransmitters flood brain receptors, producing a short-lived intense euphoria.:

Neurotransmitters flood brain receptors, producing a short-lived intense euphoria.

Inside the brain, cocaine stimulates chemical neurotransmitters, releasing intense emotions in the user. Serotonin, dopamine and norepinephrine send signals to neurons or the brain’s nerve cells.:

Inside the brain, cocaine stimulates chemical neurotransmitters, releasing intense emotions in the user. Serotonin, dopamine and norepinephrine send signals to neurons or the brain’s nerve cells.

During use, cocaine artificially increases dopamine activity and the amount of time it remains within the area of the synapses or contacts between the cells.:

During use, cocaine artificially increases dopamine activity and the amount of time it remains within the area of the synapses or contacts between the cells.

The receptors are flooded with the neurotransmitters. Serotonin elevates mood or pleasure intensifies, dopamine increases alertness and elevates arousal, and norepinephrine increases energy. :

The receptors are flooded with the neurotransmitters. Serotonin elevates mood or pleasure intensifies, dopamine increases alertness and elevates arousal, and norepinephrine increases energy.

Simultaneously, cocaine blocks the brain’s reuptake, or natural transport, of dopamine back to its site of origin.:

Simultaneously, cocaine blocks the brain’s reuptake, or natural transport, of dopamine back to its site of origin.

Even one time use appears to alter the activity of a gene in the brain. The brain and its neurotransmitter receptors negatively adapt to prolonged use of cocaine, resulting in a decreased synthesis of dopamine in the neurons.:

Even one time use appears to alter the activity of a gene in the brain. The brain and its neurotransmitter receptors negatively adapt to prolonged use of cocaine, resulting in a decreased synthesis of dopamine in the neurons.

Glucose is the energy source for the neurons, and the cocaine effect to the brain is to drastically reduce the amount of glucose present.:

Glucose is the energy source for the neurons, and the cocaine effect to the brain is to drastically reduce the amount of glucose present.

Decreased dopamine levels result in feelings of depression, anxiety, exhaustion, insomnia, or aggression and paranoia.:

Decreased dopamine levels result in feelings of depression, anxiety, exhaustion, insomnia, or aggression and paranoia.

The desire to regain this high intensity of pleasure often leads to dependence or addiction. Over time, cocaine “craving” increases rather than decreases, affording more vulnerability to relapse and repeated use. :

The desire to regain this high intensity of pleasure often leads to dependence or addiction. Over time, cocaine “craving” increases rather than decreases, affording more vulnerability to relapse and repeated use.

Users risk cocaine toxicity or an overdose.:

Users risk cocaine toxicity or an overdose.

Cocaine toxicity is linked to breathing and heart problems, increased blood pressure causing bleeding in the brain, and constriction of blood vessels causing a stroke or seizure.:

Cocaine toxicity is linked to breathing and heart problems, increased blood pressure causing bleeding in the brain, and constriction of blood vessels causing a stroke or seizure.

Addiction, contributing factors of cocaine and other substance abuse or health issues, cocaine induced heart attacks, and cocaine toxicity has led to deaths of actors, musicians, athletes, racing jockeys and people from all socioeconomic levels. :

Addiction, contributing factors of cocaine and other substance abuse or health issues, cocaine induced heart attacks, and cocaine toxicity has led to deaths of actors, musicians, athletes, racing jockeys and people from all socioeconomic levels.

A few of the lost that testify to its fatal attraction are comedian John Belusi, basketball star Leon Bias, baseball catcher Darrel Porter, advertising pitchman Billy Mays, Bobby Hatfield of the Righteous Brothers, and Whitney Houston.:

A few of the lost that testify to its fatal attraction are comedian John Belusi , basketball star Leon Bias, baseball catcher Darrel Porter, advertising pitchman Billy Mays, Bobby Hatfield of the Righteous Brothers, and Whitney Houston.

Learn more about Cocaine Effects at www.environmentaldiseases.com:

Learn more about Cocaine Effects at www.environmentaldiseases.com

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