logging in or signing up Clinial Manifestations of Dengue Fever draswinikumars Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 3341 Category: Education License: All Rights Reserved Like it (8) Dislike it (0) Added: August 31, 2009 This Presentation is Public Favorites: 3 Presentation Description Public Health Update Presentation Comments Posting comment... By: puja0107 (9 month(s) ago) i want a copy of this presentation. Saving..... Post Reply Close Saving..... Edit Comment Close By: brugiamalai (9 month(s) ago) Can you send me copy of this presentation ??? drtahirhayat@yahoo.com. Thanks in advance! Saving..... Post Reply Close Saving..... Edit Comment Close By: AgnePuthran (10 month(s) ago) Do anybody ve a copy of this presentation? if so. pls send to agneputhran@gmail.com Saving..... Post Reply Close Saving..... Edit Comment Close By: AgnePuthran (10 month(s) ago) really a very useful presentaion........ can u send a copy of ur presentation to Agneputhran@gmail.com? Saving..... Post Reply Close Saving..... Edit Comment Close By: athulgurudas (10 month(s) ago) Can I have a copy of your wonderful presentation.My email.id is athulgurudas@gmail.com Saving..... Post Reply Close Saving..... Edit Comment Close loading.... See all Premium member Presentation Transcript Clinical Manifestations of Dengue Fever/DHF/DSS : Clinical Manifestations of Dengue Fever/DHF/DSS Dr. S. Aswini Kumar. MD Professor of Medicine Govt Medical College Hospital Thiruvananthapuram 1 Dangerous Dengue : Dangerous Dengue Dengue classic Dengue Hemorrhagic Fever Dengue Shock Syndrome Death 2 Dengue is a scare! : Dengue is a scare! 3 Definition : Definition Acute febrile viral illness characterized by Fever Headache Bone pains Muscle pains Nausea & vomiting Maculopapular Rash Leucopenia & thrombocytopenia Hemorrhagic manifestations 4 Dengue Virus – Flaviviridae : Dengue Virus – Flaviviridae DEN 1 DEN 2 DEN 3 DEN 4 Infection with one serotype produces life long immunity But only temporary & partial immunity against other types 50nm 11Kb 4 SEROTYPES 5 Vector - Aedes Egypti Mosquito : Vector - Aedes Egypti Mosquito Otherwise called as Tiger Mosquitoes because of dark lines Once infected mosquito remains infected for life and able to transmit to susceptible individuals 6 How do you get it? : How do you get it? 7 Epidemiology : Epidemiology 250 250 Aedes.Aegypti is a tropical and subtropical species of mosquito 8 Dengue Epidemic – Every 2-3y : Dengue Epidemic – Every 2-3y 9 Cyclical pattern - transmission : Cyclical pattern - transmission Coincides with summer season Cool temperature affects mosquito survival 10 Transmission and Replication : Transmission and Replication 11 First Infection : First Infection 12 Second Infection : Second Infection 13 More serious infection : More serious infection Practically no antibodies are formed to neutralize the DEN 2 viruses 14 Infected monocytes : Infected monocytes Vasoactive Mediators increase Vasular Permiability 15 Immunity determination : Immunity determination 16 WHO Case Definition : WHO Case Definition 17 Dengue Clinical Syndromes : Dengue Clinical Syndromes 18 Clinical Spectrum : Clinical Spectrum Children, Travelers, Adults 19 Undifferentiated Fever : Undifferentiated Fever 20 Classical Dengue Infection : Classical Dengue Infection Generalized Maculo-papular Rash Characteristic of Dengue Fever; uncommon in DHF & DSS 21 Hemorrhagic Meanifestations : Hemorrhagic Meanifestations 22 Visible Petechiae in legs : Visible Petechiae in legs A common hemorrhagic manifestation of Dengue Fever 23 Clinical case definition for Dengue Hemorrhagic fever : Clinical case definition for Dengue Hemorrhagic fever 24 Polyserositis Common in DHF : Polyserositis Common in DHF Associated with Plasma Leakage 25 Temperature & Virus Positivity : Temperature & Virus Positivity The relation of fever, virus titer and antibody titer with time Anti Dengue IgM by Fever Day for 55 patients with Dengue IgM only reaches levels positive 2 to 3 days after the fever falls below 38°C. This is about the 6th day of illness 26 Four grades of DHF : Four grades of DHF 27 Dengue Hemorrhagic Fever : Dengue Hemorrhagic Fever 28 Thrombocytopenia in Smear : Thrombocytopenia in Smear Platelets are seen singly and the count is reduced 29 The Tourniquet Test for Dengue : The Tourniquet Test for Dengue May be mildly positive or neative in Severe case of DSS 30 Clinical case definition for Dengue Shock Syndrome : Clinical case definition for Dengue Shock Syndrome 31 Signs and Symptoms of encephalitis/encephalopathy : Signs and Symptoms of encephalitis/encephalopathy 32 Dengue Encephalopathy : Dengue Encephalopathy 33 Warning signs -Dengue Shock : Warning signs -Dengue Shock 34 Other Fevers for Diagnosis : Other Fevers for Diagnosis 35 Slide 36: 36 You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
Clinial Manifestations of Dengue Fever draswinikumars Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 3341 Category: Education License: All Rights Reserved Like it (8) Dislike it (0) Added: August 31, 2009 This Presentation is Public Favorites: 3 Presentation Description Public Health Update Presentation Comments Posting comment... By: puja0107 (9 month(s) ago) i want a copy of this presentation. Saving..... Post Reply Close Saving..... Edit Comment Close By: brugiamalai (9 month(s) ago) Can you send me copy of this presentation ??? drtahirhayat@yahoo.com. Thanks in advance! Saving..... Post Reply Close Saving..... Edit Comment Close By: AgnePuthran (10 month(s) ago) Do anybody ve a copy of this presentation? if so. pls send to agneputhran@gmail.com Saving..... Post Reply Close Saving..... Edit Comment Close By: AgnePuthran (10 month(s) ago) really a very useful presentaion........ can u send a copy of ur presentation to Agneputhran@gmail.com? Saving..... Post Reply Close Saving..... Edit Comment Close By: athulgurudas (10 month(s) ago) Can I have a copy of your wonderful presentation.My email.id is athulgurudas@gmail.com Saving..... Post Reply Close Saving..... Edit Comment Close loading.... See all Premium member Presentation Transcript Clinical Manifestations of Dengue Fever/DHF/DSS : Clinical Manifestations of Dengue Fever/DHF/DSS Dr. S. Aswini Kumar. MD Professor of Medicine Govt Medical College Hospital Thiruvananthapuram 1 Dangerous Dengue : Dangerous Dengue Dengue classic Dengue Hemorrhagic Fever Dengue Shock Syndrome Death 2 Dengue is a scare! : Dengue is a scare! 3 Definition : Definition Acute febrile viral illness characterized by Fever Headache Bone pains Muscle pains Nausea & vomiting Maculopapular Rash Leucopenia & thrombocytopenia Hemorrhagic manifestations 4 Dengue Virus – Flaviviridae : Dengue Virus – Flaviviridae DEN 1 DEN 2 DEN 3 DEN 4 Infection with one serotype produces life long immunity But only temporary & partial immunity against other types 50nm 11Kb 4 SEROTYPES 5 Vector - Aedes Egypti Mosquito : Vector - Aedes Egypti Mosquito Otherwise called as Tiger Mosquitoes because of dark lines Once infected mosquito remains infected for life and able to transmit to susceptible individuals 6 How do you get it? : How do you get it? 7 Epidemiology : Epidemiology 250 250 Aedes.Aegypti is a tropical and subtropical species of mosquito 8 Dengue Epidemic – Every 2-3y : Dengue Epidemic – Every 2-3y 9 Cyclical pattern - transmission : Cyclical pattern - transmission Coincides with summer season Cool temperature affects mosquito survival 10 Transmission and Replication : Transmission and Replication 11 First Infection : First Infection 12 Second Infection : Second Infection 13 More serious infection : More serious infection Practically no antibodies are formed to neutralize the DEN 2 viruses 14 Infected monocytes : Infected monocytes Vasoactive Mediators increase Vasular Permiability 15 Immunity determination : Immunity determination 16 WHO Case Definition : WHO Case Definition 17 Dengue Clinical Syndromes : Dengue Clinical Syndromes 18 Clinical Spectrum : Clinical Spectrum Children, Travelers, Adults 19 Undifferentiated Fever : Undifferentiated Fever 20 Classical Dengue Infection : Classical Dengue Infection Generalized Maculo-papular Rash Characteristic of Dengue Fever; uncommon in DHF & DSS 21 Hemorrhagic Meanifestations : Hemorrhagic Meanifestations 22 Visible Petechiae in legs : Visible Petechiae in legs A common hemorrhagic manifestation of Dengue Fever 23 Clinical case definition for Dengue Hemorrhagic fever : Clinical case definition for Dengue Hemorrhagic fever 24 Polyserositis Common in DHF : Polyserositis Common in DHF Associated with Plasma Leakage 25 Temperature & Virus Positivity : Temperature & Virus Positivity The relation of fever, virus titer and antibody titer with time Anti Dengue IgM by Fever Day for 55 patients with Dengue IgM only reaches levels positive 2 to 3 days after the fever falls below 38°C. This is about the 6th day of illness 26 Four grades of DHF : Four grades of DHF 27 Dengue Hemorrhagic Fever : Dengue Hemorrhagic Fever 28 Thrombocytopenia in Smear : Thrombocytopenia in Smear Platelets are seen singly and the count is reduced 29 The Tourniquet Test for Dengue : The Tourniquet Test for Dengue May be mildly positive or neative in Severe case of DSS 30 Clinical case definition for Dengue Shock Syndrome : Clinical case definition for Dengue Shock Syndrome 31 Signs and Symptoms of encephalitis/encephalopathy : Signs and Symptoms of encephalitis/encephalopathy 32 Dengue Encephalopathy : Dengue Encephalopathy 33 Warning signs -Dengue Shock : Warning signs -Dengue Shock 34 Other Fevers for Diagnosis : Other Fevers for Diagnosis 35 Slide 36: 36