logging in or signing up SD- OCT by HALA dr_holi Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 1042 Category: Education License: All Rights Reserved Like it (4) Dislike it (0) Added: November 08, 2010 This Presentation is Public Favorites: 4 Presentation Description No description available. Comments Posting comment... By: dr_holi (10 month(s) ago) thnx Saving..... Post Reply Close Saving..... Edit Comment Close By: drbillal (10 month(s) ago) The great presentation............. on Spectral Domain OCT............ Saving..... Post Reply Close Saving..... Edit Comment Close By: ophrk (13 month(s) ago) thx u Saving..... Post Reply Close Saving..... Edit Comment Close By: dr.ahmedaboali (14 month(s) ago) G.ALLAH khyran Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide 1: Spectral Domain OPTICAL COHERENCE TOMOGRAPHY BY Hala Fathi Hannot : SD - OCT : SD - OCT The Evolution of OCT Technology : The Evolution of OCT Technology OCT 1 & 2 1996 Stratus 2002 SD-OCT 2006 26,000 400 100 20 10 5 Speed (A-scans per sec) Resolution (mm) Time domain OCT : SD - OCT Slide 6: Time Domain OCT SLD Lens Detector Data Acquisition Processing The reference mirror must move one cycle for each axial scan-> limits speed of image acquisition. Reference mirror moves back and forth Scanning mirror directs SLD beam on retina Beam splitter Broadband Light Source Creates A-scan 1 pixel at a time Final A-scan Process repeated many times to create B-scan Reference beam sample beam Interferometer Combines light from reference with reflected light from retina + = + . . . Slide 7: Spectral Domain OCT SLD Spectrometer analyzes signal by wavelength FFT Grating splits signal by wavelength Broadband Light Source Reference mirror stationary Combines light from reference with reflected light from retina Interferometer Spectral interferogram Fourier transform converts signal to typical A-scan Entire A-scan created at a single time Beam splitter SD measures all echoes of light simultaneously FFT :extracts the frequency content of a signal. : SD - OCT Slide 9: SD-OCT TD-OCT SD-OCT is 50 times faster than TD-OCT Faster than eye movements So less motion artifacts Slower than eye movements Higher speed, higher definition and higher signal. 1024 A-scans in 0.04 sec Small blood vessels IS/OS Choroidal vessels Slide 10: SD-OCT TD-OCT SD-OCT Retinal thickness and RNFL thickness measurements differ than my TD-OCT measurements. underestimates true RT True retinal thickness measurement So we can’t compare Retinal thickness and RNFL measurements obtained from the two OCT systems SD-OCT TD-OCT : SD - OCT Slide 12: Improved sensitivity and speed of scanning 10 Folds improvement in sensitivity (it measures all of the reflected light at once) Improved Coverage of the Retina Dense raster pattern SD-OCT TD-OCT 50 times faster than TD Slide 13: TD-OCT SD-OCT ONL ELM IS OS RPE Improved resolution Near histology Slide 14: 3-D & video Imaging Slide 15: Eye motion compensation SLO LSO Image Registration Transverse registration allows comparison between visits Eye tracking allows scans to be taken at the same place time after time. Tracking With Eye Tracking Without Eye Tracking Slide 16: Reproducibility Adaptive optics, media opacity Mid dilated or non dilated pupil is possible SD-OCT has better RT & RNFL measurement repeatability and reproducibility compared with TD-OCT. AO compensates for ocular aberrations which limit transverse resolution. : Segmentation Segmentation techniques make it possible to view layers individually such as ILM and RPE. : SD - OCT Slide 19: Application of SD-OCT Glaucoma Cornea & Anterior segment Retina Intraoperative uses Functional SD-OCT Slide 20: Application of SD-OCT Glaucoma Cornea & Anterior segment Intraoperative uses Functional SD-OCT Retina Slide 21: SD-OCT in Retina Slide 22: Geographic atrophy Drusen PR nuclear layer Slide 23: Choroidal neovascularization: DD between type 1 and type 2 membranes Detects small foci of fluid, PED and neurosensory detachment. Confirms that it is classic or occult CNV Monitors the response to treatment, determines the frequency and duration of IVT injections Provides quantitative measurement of activity It is a reliable method to be used for fellow up after antiVEGF injections Slide 24: Polypoidal Choroidal Vasculopathy (PCV) Slide 25: Diabetic macular edema Early detection and quantitative measurement of retinal edema. Presence or absence of cyst, sub-clinical serous macular detachment . Presence or absence of macular traction &/or epi-macular membrane. Determining the best treatment modality (laser vs IVTA vs surgery) Assessing the response to treatment, prognosis and for follow up. ERM Central Retinal Vein Occlusion : Central Retinal Vein Occlusion Slide 27: segmented surface maps of an ERM Epiretinal Membrane (ERM) Slide 28: Vitreomacular Traction Syndrome SD-OCT showed that VMT could be sub-classified into two subgroups, focal and broad Broad vitreomacular traction Focal vitreomacular traction Slide 29: Myopic traction maculopathy (MTM) retinal folding in the macular area SD-OCT clearly visualized macular pathology such as schisis , holes and myopic traction Slide 30: Macular Hole Recently intraoperative Early diagnosis and DD lamellar hole ,pseudohole more precise measuring of the hole diameter Staging Visual prognosis “size of MH” Postoperative follow up & identify patients with great chance of successful re-operation for persistent MH The predictive value LMH : LMH Cystic spaces ERM ERM Lamellar Macular Hole Idiopathic central serous chorio-retinopathy : Idiopathic central serous chorio-retinopathy Using SD-OCT findings, the degree of visual loss in CSR can be correlated with: the extent of IS/OS band disruption (which indicates damage of the outer retinal layers), presence of subfoveal defects in the IS/OS. Slide 33: Retinal dystrophies Visualization of Lipofuscin Early stage of RP Cone-rod dystrophy Stargardt disease Recent studies using SD-OCT showed that foveomacular retinoschisis in XLRS does not appear to occur in the NFL X-linked retinoschisis Slide 34: Previtelliform & vitelliform stage vitelliform macular dystrophy Slide 35: Application of SD-OCT Glaucoma Cornea & Anterior segment Intraoperative uses Functional SD-OCT Retina Glaucoma Slide 36: Structural changes precedes Functional changes It provides more information than other advanced imaging technologies : It provides more information than other advanced imaging technologies only surface topography pp NFL thickness Slide 38: SD-OCT in Glaucoma Slide 39: Neural retinal rim Cup area Normal Glaucoma ONH parameters & RNFL thickness maps RNFL TSNIT graph RNFL Thickness Map 3-D Imaging of the ONH true optic nerve topography Slide 40: nerve fiber layer ganglion cell layer inner plexiform layer GCC Glaucoma preferentially thins GCC which includes the axons cell bodies dendrites of retinal ganglion cells Selective measurement of the GCC loss AS SD-OCT allows visualization of angle structures not visible on TD-OCT scan. : AS SD-OCT allows visualization of angle structures not visible on TD-OCT scan. Anterior segment SD-OCT imaging was able to show fine superficial features in the bleb wall. Slide 42: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Cornea & Anterior segment Slide 43: OCT could provide more accurately map corneal thickness, epithelial thickness, and corneal curvatures Corneal mapping over 8 meridians(8 x 1019 a-scans) in 0.31 second High-resolution 2mm scan Stroma /Epithelium/Endothelium assessment 3D Cornea CorneaPachymetry Slide 44: Anterior segment application Slide 45: Before LASIK in screening of patients to rule out keratoconus and to estimate residual stromal bed by OCT pachymetry map. postoperative evaluation of LASIK flaps and stromal bed. planning LASIK enhancement Management of post LASIK complications post LASIK ectasia diffuse lamellar keratitis epithelial ingrowth Interface fluid syndrome LASIK Interface fluid syndrome occurs due to ocular hypertension and it can be mistaken for DLK and if treated with topical steroids as in DLK, it will be worsen. Slide 46: Planning Phototherapeutic Keratectomy PK needed .. Not A Candidate for PTK Full thickness scar It precisely measures the opacity size It helps in proper management decision When to peel. How deep to ablate. When to use transepithelial ablation. When keratoplasty is needed. When to do nothing. A Candidate for PTK After PTK Before PTK Slide 47: Keratoconus detection TD ASOCT Detects Keratoconus Thinning with OCT Pachymetric Indices Recently SD-OCT uses Gaussian Waveform which : detects the diameter and position of cones & measures focal thinning Normal reference pachymetry map Keratoconus pachymetry map Inverse normalized pachymetry map Cone is revealed Slide 48: Corneal implants (INTACS) May identify patients at risk for depth-related complications, such as too shallow placement of the segments. Depth and position Slide 49: Corneal dystrophies and diseases Fuchs corneal dystrophy with corneal guttae on the posterior corneal surface. . Localized keratitis Chronic keratitis macular corneal dystrophy with irregularity of Bowman layer Slide 50: Corneal changes after cataract surgery Folds of Descemet membrane Clear corneal incision Intraepithelial vesicles detachment detachment Slide 51: Tear minscus dry eye soft contact lens Slide 52: Accurate Corneal Power Measurement for Post-LASIK IOL Calculation It uses IOL power calculation formula which is based on posterior curvature gives accurate, repeatable measurement Slide 53: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Handheld SD-OCT Slide 54: Hand Held OCT Slide 55: Oculocutaneous Albinism Retinopathy of Prematurity shaken baby syndrome elevation of the optic nerve Pre macular fold By SD-OCT we can image premature infants, without the risk of general anesthesia Slide 56: • before and after internal limiting membrane removal (before fluid-gas exchange) 3D En face image B scan Descemet’s stripping automated endothelial keratoplasty (DSAEK) to assess the donor-host interface to find interface fluid that was clinically undetectable under the microscope Intraoperative AS SD-OCT imaging in Glaucoma is valuable during removal of the trabecular meshwork using the trabeculotome. the placement of transcanalicular shunts to guide the needle during pharmacotherapeutic injections into Schlemm’s canal such as gene transfer. Before and after membrane peel Slide 57: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Functional SD-OCT Doppler : Doppler Recently SD-OCT allows imaging of retinal and choroidal blood flow That has a value in Glaucoma (assess perfusion and in vivo RNFL birefringence that may help in more accurate RNFL thickness determinations ). : SD - OCT Slide 60: 3D,Visit-to-visit registration , En face images are Available on all listed systems Topcon –3D OCT1000 Cirrus HD OCT Spectralis (Heidelberg) Bioptogen - SDOCT Copernicus HR (Optopol) OCT SLO (OPKO/OTI) RTVue (Optovue) Slide 61: Topcon –3D OCT1000 Cirrus HD OCT Spectralis (Heidelberg) Bioptogen - SDOCT Copernicus HR (Optopol) OCT SLO (OPKO/OTI) RTVue (Optovue) : SD - OCT You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
SD- OCT by HALA dr_holi Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 1042 Category: Education License: All Rights Reserved Like it (4) Dislike it (0) Added: November 08, 2010 This Presentation is Public Favorites: 4 Presentation Description No description available. Comments Posting comment... By: dr_holi (10 month(s) ago) thnx Saving..... Post Reply Close Saving..... Edit Comment Close By: drbillal (10 month(s) ago) The great presentation............. on Spectral Domain OCT............ Saving..... Post Reply Close Saving..... Edit Comment Close By: ophrk (13 month(s) ago) thx u Saving..... Post Reply Close Saving..... Edit Comment Close By: dr.ahmedaboali (14 month(s) ago) G.ALLAH khyran Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Slide 1: Spectral Domain OPTICAL COHERENCE TOMOGRAPHY BY Hala Fathi Hannot : SD - OCT : SD - OCT The Evolution of OCT Technology : The Evolution of OCT Technology OCT 1 & 2 1996 Stratus 2002 SD-OCT 2006 26,000 400 100 20 10 5 Speed (A-scans per sec) Resolution (mm) Time domain OCT : SD - OCT Slide 6: Time Domain OCT SLD Lens Detector Data Acquisition Processing The reference mirror must move one cycle for each axial scan-> limits speed of image acquisition. Reference mirror moves back and forth Scanning mirror directs SLD beam on retina Beam splitter Broadband Light Source Creates A-scan 1 pixel at a time Final A-scan Process repeated many times to create B-scan Reference beam sample beam Interferometer Combines light from reference with reflected light from retina + = + . . . Slide 7: Spectral Domain OCT SLD Spectrometer analyzes signal by wavelength FFT Grating splits signal by wavelength Broadband Light Source Reference mirror stationary Combines light from reference with reflected light from retina Interferometer Spectral interferogram Fourier transform converts signal to typical A-scan Entire A-scan created at a single time Beam splitter SD measures all echoes of light simultaneously FFT :extracts the frequency content of a signal. : SD - OCT Slide 9: SD-OCT TD-OCT SD-OCT is 50 times faster than TD-OCT Faster than eye movements So less motion artifacts Slower than eye movements Higher speed, higher definition and higher signal. 1024 A-scans in 0.04 sec Small blood vessels IS/OS Choroidal vessels Slide 10: SD-OCT TD-OCT SD-OCT Retinal thickness and RNFL thickness measurements differ than my TD-OCT measurements. underestimates true RT True retinal thickness measurement So we can’t compare Retinal thickness and RNFL measurements obtained from the two OCT systems SD-OCT TD-OCT : SD - OCT Slide 12: Improved sensitivity and speed of scanning 10 Folds improvement in sensitivity (it measures all of the reflected light at once) Improved Coverage of the Retina Dense raster pattern SD-OCT TD-OCT 50 times faster than TD Slide 13: TD-OCT SD-OCT ONL ELM IS OS RPE Improved resolution Near histology Slide 14: 3-D & video Imaging Slide 15: Eye motion compensation SLO LSO Image Registration Transverse registration allows comparison between visits Eye tracking allows scans to be taken at the same place time after time. Tracking With Eye Tracking Without Eye Tracking Slide 16: Reproducibility Adaptive optics, media opacity Mid dilated or non dilated pupil is possible SD-OCT has better RT & RNFL measurement repeatability and reproducibility compared with TD-OCT. AO compensates for ocular aberrations which limit transverse resolution. : Segmentation Segmentation techniques make it possible to view layers individually such as ILM and RPE. : SD - OCT Slide 19: Application of SD-OCT Glaucoma Cornea & Anterior segment Retina Intraoperative uses Functional SD-OCT Slide 20: Application of SD-OCT Glaucoma Cornea & Anterior segment Intraoperative uses Functional SD-OCT Retina Slide 21: SD-OCT in Retina Slide 22: Geographic atrophy Drusen PR nuclear layer Slide 23: Choroidal neovascularization: DD between type 1 and type 2 membranes Detects small foci of fluid, PED and neurosensory detachment. Confirms that it is classic or occult CNV Monitors the response to treatment, determines the frequency and duration of IVT injections Provides quantitative measurement of activity It is a reliable method to be used for fellow up after antiVEGF injections Slide 24: Polypoidal Choroidal Vasculopathy (PCV) Slide 25: Diabetic macular edema Early detection and quantitative measurement of retinal edema. Presence or absence of cyst, sub-clinical serous macular detachment . Presence or absence of macular traction &/or epi-macular membrane. Determining the best treatment modality (laser vs IVTA vs surgery) Assessing the response to treatment, prognosis and for follow up. ERM Central Retinal Vein Occlusion : Central Retinal Vein Occlusion Slide 27: segmented surface maps of an ERM Epiretinal Membrane (ERM) Slide 28: Vitreomacular Traction Syndrome SD-OCT showed that VMT could be sub-classified into two subgroups, focal and broad Broad vitreomacular traction Focal vitreomacular traction Slide 29: Myopic traction maculopathy (MTM) retinal folding in the macular area SD-OCT clearly visualized macular pathology such as schisis , holes and myopic traction Slide 30: Macular Hole Recently intraoperative Early diagnosis and DD lamellar hole ,pseudohole more precise measuring of the hole diameter Staging Visual prognosis “size of MH” Postoperative follow up & identify patients with great chance of successful re-operation for persistent MH The predictive value LMH : LMH Cystic spaces ERM ERM Lamellar Macular Hole Idiopathic central serous chorio-retinopathy : Idiopathic central serous chorio-retinopathy Using SD-OCT findings, the degree of visual loss in CSR can be correlated with: the extent of IS/OS band disruption (which indicates damage of the outer retinal layers), presence of subfoveal defects in the IS/OS. Slide 33: Retinal dystrophies Visualization of Lipofuscin Early stage of RP Cone-rod dystrophy Stargardt disease Recent studies using SD-OCT showed that foveomacular retinoschisis in XLRS does not appear to occur in the NFL X-linked retinoschisis Slide 34: Previtelliform & vitelliform stage vitelliform macular dystrophy Slide 35: Application of SD-OCT Glaucoma Cornea & Anterior segment Intraoperative uses Functional SD-OCT Retina Glaucoma Slide 36: Structural changes precedes Functional changes It provides more information than other advanced imaging technologies : It provides more information than other advanced imaging technologies only surface topography pp NFL thickness Slide 38: SD-OCT in Glaucoma Slide 39: Neural retinal rim Cup area Normal Glaucoma ONH parameters & RNFL thickness maps RNFL TSNIT graph RNFL Thickness Map 3-D Imaging of the ONH true optic nerve topography Slide 40: nerve fiber layer ganglion cell layer inner plexiform layer GCC Glaucoma preferentially thins GCC which includes the axons cell bodies dendrites of retinal ganglion cells Selective measurement of the GCC loss AS SD-OCT allows visualization of angle structures not visible on TD-OCT scan. : AS SD-OCT allows visualization of angle structures not visible on TD-OCT scan. Anterior segment SD-OCT imaging was able to show fine superficial features in the bleb wall. Slide 42: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Cornea & Anterior segment Slide 43: OCT could provide more accurately map corneal thickness, epithelial thickness, and corneal curvatures Corneal mapping over 8 meridians(8 x 1019 a-scans) in 0.31 second High-resolution 2mm scan Stroma /Epithelium/Endothelium assessment 3D Cornea CorneaPachymetry Slide 44: Anterior segment application Slide 45: Before LASIK in screening of patients to rule out keratoconus and to estimate residual stromal bed by OCT pachymetry map. postoperative evaluation of LASIK flaps and stromal bed. planning LASIK enhancement Management of post LASIK complications post LASIK ectasia diffuse lamellar keratitis epithelial ingrowth Interface fluid syndrome LASIK Interface fluid syndrome occurs due to ocular hypertension and it can be mistaken for DLK and if treated with topical steroids as in DLK, it will be worsen. Slide 46: Planning Phototherapeutic Keratectomy PK needed .. Not A Candidate for PTK Full thickness scar It precisely measures the opacity size It helps in proper management decision When to peel. How deep to ablate. When to use transepithelial ablation. When keratoplasty is needed. When to do nothing. A Candidate for PTK After PTK Before PTK Slide 47: Keratoconus detection TD ASOCT Detects Keratoconus Thinning with OCT Pachymetric Indices Recently SD-OCT uses Gaussian Waveform which : detects the diameter and position of cones & measures focal thinning Normal reference pachymetry map Keratoconus pachymetry map Inverse normalized pachymetry map Cone is revealed Slide 48: Corneal implants (INTACS) May identify patients at risk for depth-related complications, such as too shallow placement of the segments. Depth and position Slide 49: Corneal dystrophies and diseases Fuchs corneal dystrophy with corneal guttae on the posterior corneal surface. . Localized keratitis Chronic keratitis macular corneal dystrophy with irregularity of Bowman layer Slide 50: Corneal changes after cataract surgery Folds of Descemet membrane Clear corneal incision Intraepithelial vesicles detachment detachment Slide 51: Tear minscus dry eye soft contact lens Slide 52: Accurate Corneal Power Measurement for Post-LASIK IOL Calculation It uses IOL power calculation formula which is based on posterior curvature gives accurate, repeatable measurement Slide 53: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Handheld SD-OCT Slide 54: Hand Held OCT Slide 55: Oculocutaneous Albinism Retinopathy of Prematurity shaken baby syndrome elevation of the optic nerve Pre macular fold By SD-OCT we can image premature infants, without the risk of general anesthesia Slide 56: • before and after internal limiting membrane removal (before fluid-gas exchange) 3D En face image B scan Descemet’s stripping automated endothelial keratoplasty (DSAEK) to assess the donor-host interface to find interface fluid that was clinically undetectable under the microscope Intraoperative AS SD-OCT imaging in Glaucoma is valuable during removal of the trabecular meshwork using the trabeculotome. the placement of transcanalicular shunts to guide the needle during pharmacotherapeutic injections into Schlemm’s canal such as gene transfer. Before and after membrane peel Slide 57: Application of SD-OCT Glaucoma Intraoperative uses Functional SD-OCT Retina Cornea & Anterior segment Functional SD-OCT Doppler : Doppler Recently SD-OCT allows imaging of retinal and choroidal blood flow That has a value in Glaucoma (assess perfusion and in vivo RNFL birefringence that may help in more accurate RNFL thickness determinations ). : SD - OCT Slide 60: 3D,Visit-to-visit registration , En face images are Available on all listed systems Topcon –3D OCT1000 Cirrus HD OCT Spectralis (Heidelberg) Bioptogen - SDOCT Copernicus HR (Optopol) OCT SLO (OPKO/OTI) RTVue (Optovue) Slide 61: Topcon –3D OCT1000 Cirrus HD OCT Spectralis (Heidelberg) Bioptogen - SDOCT Copernicus HR (Optopol) OCT SLO (OPKO/OTI) RTVue (Optovue) : SD - OCT