Slide 2:
Bronchial Asthma Chronic respiratory disease
Increased response of Tracheo-bronchial tree
Narrowing of airways
Hypersecretion of viscid mucus
Leads to Dyspnoea, cough and wheezing
Limitation is reversible
Spontaneously
Thru medications What is it ?? What Happens In Bronchial Asthma What does that cause ???
Slide 3:
How does the Hyper responsiveness set in ?? Main Culprit = Allergen IgE Antigen antibody Reaction Broncho constriction Symptoms Stimulation of Immune system by allergens leads to formation of Ig E
Slide 4:
IgE Allergen Ag Presentation IL-3, IL-5 LTC4, MBP, ECP TXA2, LTC4, LTB4, PAF IL-4 Histamine
PGD2
LTC4 Macrophage T4- Helper Eosinophil Plasma Cell Mast Cell TXA – thromboxane A2
LTC4 – leucotriene c4
LTB4 – leucotriene B4
PAF – Platelet Activating Factor MBP – Major Basic protein
ECP – Eosinophil cationic Protein IL - Interleukin Acute Inflammation Mediators Kills Epithelium BASIC PATHOLOGY
Slide 5:
Is Asthma Always Caused by Allergens ?? NO How Can We differentiate Asthma ?? Classify Asthma Classification of Asthma
Slide 6:
Clinical Presentations Episodic Attack Status Asthamatics Chronic Asthma Patient Symptoms
Clinical features
Inspection
Palpation/percussion
Auscultation How Does Asthma present ?? Always Describe diseases in following manner
Slide 7:
Join
Pulse MBBS & BDS Tutorials.
to
Study in
highly simplified & interactive way pulse.tutorials@gmail.com MBBS: 9768721525
BDS : 9768723448