Capping of the 5' end of pre-mRNA

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5' Cap RNA video

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Presentation Transcript

Slide 1: 

The terminal phosphate is removed by hydrolysis A 5’-5’ triphosphate bond forms as the G residue is added to the 5’ end The G group is methylated by adding a methyl group Other methyl groups may be added to the ribose Wiki group 29, UCD 5’ Capping RNA

Slide 2: 

N N H2N N + CH3 N O P P P O OH OH Base 1 Base 2 7’ Methylgaunosine The 5’- 5’ triphosphate linkage Base 4 Base 3 P P P P ……… Pre-mRNA