brain chip ppt

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Presentation Description

thisis about brain on a microchip

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Presentation Transcript

The Wired BrainMotive, Means, & Opportunity : 

The Wired BrainMotive, Means, & Opportunity Ramez Naam mez@apexnano.com

Motive : 

Motive Help the sick & injured

Means : 

Means Brain and nervous system prosthesis

Opportunity : 

Opportunity Neural prosthesis to enhance human brains

Motives : 

Motives

The Deaf : 

The Deaf ~20 million hearing impaired people in US ~2 million cannot be helped by hearing aids

The Blind : 

The Blind 1.3 million people in the US

The Paralyzed : 

The Paralyzed 2 million people in the US

Parkinson’s Disease : 

Parkinson’s Disease 1.5 million people in the US

Permanent Brain Injury : 

Permanent Brain Injury Problems with: attention memory learning perception mood 5.3 million people in the US

And Many More : 

And Many More stroke victims the severely depressed obsessive compulsive disorder sufferers

Slide 12: 

> 10 million potential patients in the US

Means : 

Means

The Brain is Electrochemical : 

The Brain is Electrochemical 1870 – Fritsch and Hitzig Moved dog limbs by electrically stimulating the brain

Human Cognition is Electrochemical : 

Human Cognition is Electrochemical 1950 – Wilder Penfield Produced spontaneous memories byelectrically stimulating the brain

Neural Interfaces Can Control Behavior : 

Neural Interfaces Can Control Behavior 1960s - Jose Delgado & Robert Heath

Delgado Animal Manipulation : 

Delgado Animal Manipulation Sleep Appetite Aggression Pleasure & Pain Social Dominance

Aggression : 

Aggression

Aggression : 

Aggression

Heath Human Experiments : 

Heath Human Experiments “neuro-orgasms” professions of love attempted to “cure homosexuality”

Slide 21: 

creepy

Slide 22: 

medical uses

Restore Hearing : 

Restore Hearing 1970s – The Cochlear Implant Restores Hearing to Completely Deaf

Cochlear Implant : 

Cochlear Implant electrically stimulates the auditory nerve

Primitive Electronics, Big Results : 

Primitive Electronics, Big Results Cochlear Implant < 30 electrodes Auditory Nerve 30,000 neurons couldn’t possibly work produces 90% word recognition

Restoring Vision : 

Restoring Vision

Restoring Vision : 

Restoring Vision

Primitive Electronics, Big Results : 

Primitive Electronics, Big Results Visual Prosthesis 256 electrodes Visual Cortex billions of neurons couldn’t possibly work “limited mobility” vision

Cortical Visual Implant Video : 

Cortical Visual Implant Video

Controlling Motion : 

Controlling Motion

Primitive Electronics, Big Results : 

Primitive Electronics, Big Results Motor Prosthesis 1 wireless electrode Motor Cortex billions of neurons couldn’t possibly work provides useful control of cursor or robot arm

Controlling Devices : 

Controlling Devices

What’s Happening Here? : 

What’s Happening Here? cracking the code of the brain that code is distributed good results with sparse connections

Controlling Parkinson’s : 

Controlling Parkinson’s all Parkinson’s drugsfail over time

Controlling Parkinson’s Disease : 

Controlling Parkinson’s Disease Deep Brain Stimulator

Deep Brain Stimulator : 

Deep Brain Stimulator more than 30,000 installed 8-10 hour surgery $40,000 bill Recently covered by Medicare

Deep Brain Stimulator Side Effects : 

Deep Brain Stimulator Side Effects Untreatable Depression Normal Mood

Deep Brain Stimulator Side Effects : 

Deep Brain Stimulator Side Effects Uncontrolled Obsessive Compulsive Behavior Normal Behavioral Control

Deep Brain Stimulator Side Effects : 

Deep Brain Stimulator Side Effects Clinical trials for Depression & OCD Underway other conditions under consideration

Slide 40: 

a return to emotion and behavior but in a medical context

Technology Trends : 

Technology Trends

Neural Interface Electronics : 

Neural Interface Electronics

Enter the Electrical Engineers : 

Enter the Electrical Engineers UMich Neural Chip 1024 electrodes Wireless Infineon Neuro-Chip 16,384 electrodes

Plenty of Room To Improve : 

Plenty of Room To Improve 55 million transistors

Opportunities : 

Opportunities

Restoring Damaged Memory? : 

Restoring Damaged Memory?

Repairing the Hippocampus : 

Repairing the Hippocampus

Hippocampus Chip : 

Hippocampus Chip “dumb” replica of the hippocampus will help us crack the code of memory

Enhancing Memory? : 

Enhancing Memory? In 2006 Berger & Deadwyler willattach hippocampus chip to a healthy primate’s hippocampus

Enhancing Memory? : 

Enhancing Memory? In 2006 it probably won’t work we’ll learn from the attempt someday soon it will work

Beyond Memory : 

Beyond Memory some possibilities

Beyond Memory : 

Beyond Memory Language Chip Broca & Wernicke’s areas ultimate text input method?

Beyond Memory : 

Beyond Memory Emotion Chip amygdala & other areas

Emotional Chip Advantages : 

Emotional Chip Advantages Drugs slow to act slow to stop acting shotgun approach ( = side effects) not very tunable no feedback Neural Stimulation immediate stops on a dime laser-like precision extremely fine-tunable instant feedback

Autonomous Behavioral Conditioning : 

Autonomous Behavioral Conditioning broccoli = good exercise = good saturated fat = bad

Risks of Self Conditioning : 

Risks of Self Conditioning ultimate high 1500 self-stimulations per hour ultimate addiction hardware limitations

Beyond Memory : 

Beyond Memory Frontal Cortex Chip “working memory” attention reasoning decision making

Communication : 

Communication to the brain, imagination = sensation = memory

Communication : 

Communication the same neurons fire when you see an image when you remember that image when you imagine an image just like it

Communication : 

Communication so if we can send images, sounds, sensations into your brain you can send them out of your brain into a computer or another person’s brain

Vanderbilt Experiment : 

Vanderbilt Experiment monkey #1auditory cortex monkey #2 auditory cortex Brain Computer Interface

What Else Could We Communicate? : 

What Else Could We Communicate? Sound, Sight, Touch, Taste, Smell Almost Certainly Emotions? Probably Memories? Knowledge? Skills? Maybe someday but not soon

Major Changes To : 

Major Changes To human self-determination human-to-human communication

The Hurdles : 

The Hurdles

Hurdles – Brain Surgery : 

Hurdles – Brain Surgery Risky Expensive New surgery for each upgrade? Conclusion: it will never happen

What About Eye Surgery? : 

What About Eye Surgery? Risky Expensive May get stuck with less than 20/20 vision Glasses are a fine alternative Conclusion: it will never happen Laser Surgery Changed the Rules

LASIK : 

LASIK had risk, cost, and non-surgical alternatives sufficiently safe sufficiently cheap sufficient benefit (convenience) revolutionized eye surgery

Eye Surgeries Per Year : 

Eye Surgeries Per Year

Refractive Eye Surgery Cost : 

Refractive Eye Surgery Cost

Possible Brain Surgery Revolutions : 

Possible Brain Surgery Revolutions Stereotactic Surgery (magnets, images, and robots) Neurovascular Surgery (enter through arteries instead of the skull)

Neurovascular Stereotactic Surgery : 

Neurovascular Stereotactic Surgery

Neurovascular Stereotactic Surgery : 

Neurovascular Stereotactic Surgery

Magnetic Fields Guide Catheter : 

Magnetic Fields Guide Catheter

Results : 

Results 12 hour surgeries now take 90 minutes with less risk, better outcomes $40,000 aneurysm operations now cost $4,000

Slide 75: 

brain surgery is destined to become fast, safe, and easy

Hurdle - Upgrades : 

Hurdle - Upgrades only the interface electronics go inside the brain the rest sit on the outside

Alternative to Brain Surgery : 

Alternative to Brain Surgery Wearable computing: PDAs for memory Contact-lens displays Throat microphones

Alternative to Brain Surgery : 

Alternative to Brain Surgery Poor substitutes for: instant, precise emotional control audio, visual, tactile, emotional telepathy improved memory, attention, and cognition and more

Recap : 

Recap

Motive : 

Motive (for now)

help the sick : 

help the sick

Means : 

Means

neural – computer interfaces : 

neural – computer interfaces

in their infancy : 

in their infancy

rapidly improving : 

rapidly improving

Opportunity : 

Opportunity

enhance memory & cognition : 

enhance memory & cognition

increase human self-determination : 

increase human self-determination

expand modes of human communication : 

expand modes of human communication

The Risk Takers : 

The Risk Takers

Slide 91: 

Those who’ve suffered will be the first enhanced

Backup Slides : 

Backup Slides

Computer Mediated Communication : 

Economics Neuroscience ? Freedom Computer Mediated Communication Bill Jane