Arrive Guidelines for Preclinical Studies

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ARRIVE guidelines are important for good reporting of the research conducted on animals. There are various advantages to following ARRIVE guidelines.


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Arrive Guidelines for Preclinical Studies: Importance in Bioscience Research Reporting


ARRIVE guidelines are important for good reporting of the research conducted on animals. There are various advantages to following ARRIVE guidelines. Following these guidelines will increase validity and transparency in research articles and will become the guiding light for further research. Introduction


In the present times, several journals are involved in publishing the latest researches on biosciences. To provide accurate information to the readers, good bioscience reporting related to the  preclinical studies  is of utmost importance.  Following are the various advantages of good bioscience reporting in articles related to pre-clinical studies: Need and Importance of Good Reporting


Quality information dissemination:  Good reporting ensures that quality information is disseminated in the scientific community. Helpful in advanced research:  When the research article report of high-level, and all the minute information are presented in a detailed manner, it will become a guiding light for further research, whether a preclinical or clinical. Optimum utilization of resources:   Good reporting helps the researchers all over the world to make optimum utilization of resources. It has been found that bad scientific reporting has ethical, scientific, and economic repercussions.


Make the research more relevant:  Good reporting helps the researcher to make its research more relevant among the scientific community. If the reporting of  preclinical research  is of high-quality, other authors will use it as a reference which increases the authenticity of research . Effective peer review process:   Most journals conduct a peer-review process. Good journals have a stringent peer-review process and substandard reporting of the research may lead to rejection of the article for publication. It has been found that many articles do have the hypothesis or the objective of the research while some have not reported the animal selection criteria or the type of research.


Why ARRIVE Guidelines is Required? ARRIVE (Animals in Research: Reporting In-vivo Experiments) guidelines were developed for accurately reporting animal research. These guidelines make use of the guidelines mentioned in the CONSORT statement. The main aim of ARRIVE guidelines is to increase the quality of research reporting by improving the quality and quantity of information and to avoid unnecessary studies involving animals.


ARRIVE Guidelines ARRIVE guidelines provides a list of information that should be incorporated in reporting research in a  scientific article  related to animals. 20 items should be reported in the articles. To increase its validity and authenticity, the ARRIVE guidelines are prepared by taking inputs from researchers,  journal editors , research funders, and statisticians. Following are the items that should be included in the research study according to  ARRIVE guidelines :


Title:  Title is an important part of the research article. It should be clear and concise which depicts the research as closely as possible . Abstract:  Abstract is a brief about the complete study. The abstract should include research objectives, background, methods, key findings, and the conclusion . Introduction:  The introduction includes background and objectives. The background explains what has already been done before the research in context. Primary and secondary objectives define what the researcher wants to achieve with the research.


Methods:  Methods include study designs, ethical procedures, experimental methods, animals, sample size, housing and husbandry, the outcome of the experiment, and statistical methods used. Results :  The result should be provided in detail in the research article. The results should be directed upon primary and secondary objectives. Discussion :  This section will determine how the outcome of your research fits in context to other similar types of researches. The study objectives and hypotheses are discussed in detail in comparison to prior literature.


REFERENCE Kilkenny C, Browne WJ, Cuthi I, Emerson M, Altman DG. Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. Vet Clin Pathol . 2012;41(1):27-31. doi:10.1111/j.1939-165X.2012.00418.x


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