nuclear receptor screening

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Nuclear receptors (NRs) are a class of proteins responsible for sensing steroid and thyroid hormones and certain other molecules. There are 48 genes in the human genome that code for the NRs. The myriad molecular pathways modulated by NRs including but not limited to inflammation, lipid metabolism, apoptosis, extracellular matrix regulation, energy metabolism, and angiogenesis. https://www.creative-biogene.com/Services/Drug-Discovery-Services/Nuclear-Receptor-Screening-Assays.html

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Nuclear Receptor Screening:

Nuclear Receptor Screening Creative Biogene offers a broad portfolio of assays to meet your project objectives. Our comprehensive nuclear receptor assays are including HTS, IC50 determination and selectivity, glucocorticoid receptor, progesterone receptor, androgen receptor, mineralocorticoid receptor, ror gamma t receptor, estrogen receptor, retinoic acid receptor binding and profiling assays. Other than existing assays, Creative Biogene has also developed customized assays for the clients. Our nuclear receptor experts can provide the highest quality data under rapid turnaround time evaluating your compounds’ efficacy, potency, and selectivity to make the critical decisions regarding compound liabilities. If you plan to set up a nuclear receptor screening and profiling program, we are here to help. Nuclear receptors (NRs) are a class of proteins responsible for sensing steroid and thyroid hormones and certain other molecules. There are 48 genes in the human genome that code for the NRs. The myriad molecular pathways modulated by NRs including but not limited to inflammation, lipid metabolism, apoptosis, extracellular matrix regulation, energy metabolism, and angiogenesis. These pathways’ processes can impact human health, such as general homeostasis, growth, and proliferation, which enable NRs to become the important therapeutic targets in the pathology of cancer, inflammation, and many other diseases for decades.

Advantages of nuclear receptor profiling:

Advantages of nuclear receptor profiling . Screening and profiling of a broad range of nuclear receptors . Information on an essential family of receptors responsible for a wide range of on- and off-target biological processes . Our unparalleled expertise and cutting-edge know-how create an unprecedented and extremely competitive integrated NR drug discovery platform

Contact information :

Contact information Provider: Creative Biogene URL: https://www.creative-biogene.com/Services/Drug-Discovery-Services/Nuclear-Receptor-Screening-Assays.html Address: 45-1 Ramsey Road, Shirley, NY 11967, USA Phone No. 1-631-619-7922

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