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Can a very common allergy medicine improve survival among patients suffering from the serious skin cancer, malignant melanoma? A new study from Lund University in Sweden indicates that this may be the case. Visit -


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Can a very common allergy medicine improve survival among patients suering from the serious skin cancer malignant melanoma A new study from Lund University in Sweden indicates that this may be the case. In the study the researchers examined the use of six antihistamines in patients diagnosed with malignant melanoma desloratadine cetirizine loratadine clemastine ebastine and fexofenadine. Melanoma is a type of skin cancer that develops when the mel- anocytes the cells that give the skin its tan or brown color start to grow out of control. Melanoma is much less common than some other types of skin cancers. But melanoma is more dangerous because it is much more likely to spread to other parts of the body if not caught and treated early. “Previous studies have shown that the same antihistamines have survival benets in breast cancer. Now we see the same thing concerning malignant mela- noma. However more research is required to conrm the results ” emphasizes Prof. Håkan Olsson. He is one of the researchers behind the study which was recently published in the research journal Allergy.

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They have matched information from three large clinical registries the prescribed drug registry cancer registry and cause of death registry for everyone in Sweden between 2006 and 2014 who received their rst diagnosis of skin cancer a total of 24562 individuals. Of these individuals 1253 were antihistamine users. Most used desloratadine 395 cetirizine 324 loratadine 251 or clemastine 192.The other antihistamines were used by considera- bly fewer individuals. The follow-up of individuals was carried out on 31 December 2018. “We observed improved survival among those who used desloratadine and to a certain extent also loratadine particularly in the age group 65 and older when we compared with those who had not used antihistamines. The use of the other antihistamines showed no signicant survival eect. The use of deslo- ratadine and loratadine also seemed to reduce the risk of getting a new malignant melanoma” says Prof. Håkan Olsson. “The nding is interesting for a future drug against melanoma and may also help in advanced stages of the disease. In addition the medicines have virtually no side eects. ”The research team is now planning animal experiments and randomized studies in order to understand the mechanisms behind the eect the appropriate dose and optimum treatment period. “We are collaborating with researchers in Barcelona and Stockholm. In Lund we are underway with studies in both animal and human subjects in which doses of antihistamines will be compared with the patients who do not take antihistamines in order to measure the treatment eect” concludes Prof. Håkan REFERENCE 1. Lund University. 2020 May 11. Antihistamines may help patients with malignant melanoma. ScienceDaily. Retrieved May 17 2020 from 2. Eurekalert. 2020 May 14. “Allergy Medications May Treat Malignant Melanoma Patients” . Medindia. Retrieved May 17 2020 from 3. American Cancer Society. n.d.. “What Is Melanoma Skin Cancer” Retrieved May 17 2020 from IMAGE GLOSSARY 1. 603838000sourceimagescdvfeved0CAIQjRxqFwoTCKDN7uWs1OkCFQAAAAAdAAAAABAD 2. news.com2Fantihistamines-may-help-patients-with-malignant-melanoma2FpsigAOvVaw1t_IqokHJMuNxTXfcZ1FO7ust1590676358415000sourcei magescdvfeved0CAIQjRxqFwoTCOivw_Ss1OkCFQAAAAAdAAAAABAD 3. terstock.com2Fimage-photo2Fkyiv-ukrainemay-27-2019-loratadine-medication-1408679642psigAOvVaw3B_mEOlpOjRMdWY80TXFefust159067810 7185000sourceimagescdvfeved0CAIQjRxqFwoTCJDH4Yut1OkCFQAAAAAdAAAAABAX 4. terstock.com2Fimage-photo2Fkyiv-ukrainemay-25-2019-fexofenadine-medication-1406925812psigAOvVaw3B_mEOlpOjRMdWY80TXFefust1590678 107185000sourceimagescdvfeved0CAIQjRxqFwoTCJDH4Yut1OkCFQAAAAAdAAAAABAc 5. est.com2Fpin2F3303813226488117072FpsigAOvVaw3B_mEOlpOjRMdWY80TXFefust1590678107185000sourceimagescdvfeved0CAIQjRx qFwoTCJDH4Yut1OkCFQAAAAAdAAAAABAn 6. dical.net2Fhealth2FLong-Term-Eects-of-Taking-Allergy-Medications.aspxpsigAOvVaw3B_mEOlpOjRMdWY80TXFefust1590678107185000sourcei magescdvfeved0CAIQjRxqFwoTCJDH4Yut1OkCFQAAAAAdAAAAABBX

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