don’t miss the trali:
don’t miss the trali Transfusion Related Acute Lung Injury
Transfusion Related Acute Lung Injury:
Transfusion Related Acute Lung Injury Dyspnea Hypotension Cyanosis Non-Cardiogenic pulmonary edema Hypoxia (60-70% on O2) Tachycardia Fever Occurs within 2-6 hours after starting a transfusion
Treatment for trali:
Treatment for trali Treatment includes O2 , O2, O2. Position patient’s on their stomachs for at least 12 hours. If severe, intubation and fluid resuscitation with crystalloids or colloids and albumin.
Watch for the taco:
Watch for the taco Transfusion Associated Circulatory Overload
Transfusion Associated Circulatory overload:
Transfusion Associated Circulatory overload Dyspnea Hypertension Peripheral Edema Cardiogenic Pulmonary Edema Hypoxia (60-70%)
Treatment for TACo:
Treatment for TACo Treatment includes diuretic (Lasix). A definitive differential diagnosis is vital before considering treatment with Lasix which can put a hypotensive patient with TRALI into intractable hypotension.
Trali vs. taco:
Trali vs. taco Trali Hypotension* Dyspnea Hypoxia Low O2 TACO Hypertension* Dyspnea Hypoxia Low O2
Interesting facts about trali :
Interesting facts about trali Plasma is no longer accepted from female donors in the United Kingdom. Plasma from multiparous female donors can carry human leukocyte antigen (HLA)-specific antibodies that react to the antigen of the person receiving the blood product which is a major factor of TRALI. Stored blood products develop active lipids that can attack the neutrophils, a process that leads to rupturing and destroying the lung’s endothelial lining, this may be a factor that causes TRALI.