Fluid Mosaic Model

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FLUID MOSAIC MODEL : 

FLUID MOSAIC MODEL 1 M.Bregar (Dante C.S.S.)

FLUID MOSAIC MODEL : 

FLUID MOSAIC MODEL Model describing structure of the cell membrane Model says model cell membrane is not solid, fluid. Has the consistency of olive oil 2 M.Bregar (Dante C.S.S.)

FLUID MOSAIC MODEL : 

FLUID MOSAIC MODEL 3 M.Bregar (Dante C.S.S.)

FLUID MOSAIC MODEL : 

FLUID MOSAIC MODEL 4 M.Bregar (Dante C.S.S.)

Slide 5: 

FUNCTIONS OF PLASMA MEMBRANE 5 M.Bregar (Dante C.S.S.)

PHOTOGRAPH OF CELL MEMBRANE : 

PHOTOGRAPH OF CELL MEMBRANE CELL MEMBRANE 6 M.Bregar (Dante C.S.S.)

FUNCTIONS OF PLASMA MEMBRANE : 

FUNCTIONS OF PLASMA MEMBRANE Protective barrier Regulates movement of substances in / out of cell (selectively permeable) Allows for cell recognition 7 M.Bregar (Dante C.S.S.)

FUNCTIONS OF PLASMA MEMBRANE : 

FUNCTIONS OF PLASMA MEMBRANE Cell membranes have junctions – surfaces which interlock keeps cells together Provides binding site for enzymes Contains cytoplasm (contents of the cell) 8 M.Bregar (Dante C.S.S.)

GAP JUNCTIONS : 

GAP JUNCTIONS ENDOTHELIAL JUNCTION 9 M.Bregar (Dante C.S.S.)

Slide 10: 

10 M.Bregar (Dante C.S.S.)

Slide 11: 

STRUCTURE OF PLASMA MEMBRANE 11 M.Bregar (Dante C.S.S.)

MEMBRANE COMPONENTS : 

MEMBRANE COMPONENTS Proteins (intergral & peripheral) Carbohydrates (glucose) Phospholipids Cholesterol 12 M.Bregar (Dante C.S.S.)

PHOSPHOLIPIDS : 

PHOSPHOLIPIDS Make up 30-50% of the cell membrane Phospholipids are like triglycerides with a phosphate Come together to make a fluid membrane 13 M.Bregar (Dante C.S.S.)

CLOSER LOOK OF THE PLASMA MEMBRANE : 

CLOSER LOOK OF THE PLASMA MEMBRANE 14 M.Bregar (Dante C.S.S.)

PHOSPHOLIPIDS : 

PHOSPHOLIPIDS 15 M.Bregar (Dante C.S.S.)

Slide 16: 

PHOSPHATE HEAD – HYDROPHYLIC FATTY ACID TAILS – HYDROPHOBIC 16 M.Bregar (Dante C.S.S.)

PHOSPHOLIPID ORIENTATION : 

PHOSPHOLIPID ORIENTATION PHOSPHATE HEADS – are water loving and point toward water FATTY ACID TAILS – are water fearing and orient themselves to each other 17 M.Bregar (Dante C.S.S.)

PHOSPHOLIPID ORIENTATION : 

PHOSPHOLIPID ORIENTATION In water, phospholipids form a bilayer A cell membrane is a bilayer 18 M.Bregar (Dante C.S.S.)

PHOSPHOLIPID ORIENTATION : 

PHOSPHOLIPID ORIENTATION Liposome is a small vesicle, with an aqueous compartment surrounded by a bilayer 19 M.Bregar (Dante C.S.S.)

Slide 20: 

20 M.Bregar (Dante C.S.S.)

PHOSPHOLIPIDS : 

PHOSPHOLIPIDS Weak hydrogen bonds keep phospholipids together to make the cell membrane Hydrogen bonds occur between phosphate heads 21 M.Bregar (Dante C.S.S.)

PROTEINS : 

PROTEINS Proteins make up about 50% of the cell membrane Various types of proteins 22 M.Bregar (Dante C.S.S.)

PROTEINS : 

PROTEINS M.Bregar (Dante C.S.S.) 23

INTEGRAL PROTEINS : 

INTEGRAL PROTEINS Proteins which are surrounded by phospholipids Functions: serve as ion channels, membrane pumps, or receptors 24 M.Bregar (Dante C.S.S.)

INTEGRAL PROTEINS : 

INTEGRAL PROTEINS 25 M.Bregar (Dante C.S.S.)

INTEGRAL PROTEINS : 

INTEGRAL PROTEINS 26 M.Bregar (Dante C.S.S.)

PERIPHERAL PROTEINS : 

PERIPHERAL PROTEINS Proteins which attach to the membrane Do not interact with lipids, but with integral proteins Attach by weak hydrogen bonds 27 M.Bregar (Dante C.S.S.)

PERIPHERAL PROTEINS : 

PERIPHERAL PROTEINS 28 M.Bregar (Dante C.S.S.)

CHOLESTEROL : 

CHOLESTEROL Involved in keeping membrane “fluid” Stiffens the outside of the membrane Keeps the inside of the membrane fluid 29 M.Bregar (Dante C.S.S.)

Slide 30: 

30 M.Bregar (Dante C.S.S.)

GLYCOPROTEINS : 

GLYCOPROTEINS GLYCOPROTEINS found on the surface of the membrane Serve as recognition sites for chemicals Involved in cell to cell interactions 31 M.Bregar (Dante C.S.S.)

GLYCOLIPIDS : 

GLYCOLIPIDS Between phospholipids Face extracellular fluid and serve as “cell identifiers” M.Bregar (Dante C.S.S.) 32

GLYCOLIPIDS : 

M.Bregar (Dante C.S.S.) 33 GLYCOLIPIDS