Mireica Training Manual

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Why External Skincare is not Enough? Top layer (Epidermis) – where skincare creams work, is less than 10% of the skin total thickness. 2nd Layer (Dermis) – overall structure, resilience and appearance of the top layer depends on health of dermis Skin stem cells – some very high end skincare just beginning to target skin stem cells Know Your Skin 3 layers – Epidermis, Dermis & Subcutis Visible signs of ageing reflects what’s happening at the dermis Unhealthy skin cells show up as skin problems & imperfections Skin stem cells play the most important role in maintaining and repairing of damaged skin

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Importance of Skin Supplements Ability to reach deep into the dermis layer (structural damage at dermis shows up on the surface as wrinkles) Effective in delivering large amounts of advance ingredients Industry report: USD1.5b in 2009 will grow to USD2.5b by 2012 Evolution of Skin Supplements Generations of Skin Supplement 1G – Skin Food (Marine protein, collagen) 2G – Anti-Oxidants (Vitamins C&E) 3G – UV Protection (special ingredients) 4G – Skin Stem Cells (plant stem cell extract)

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The MIREICA Breakthrough First and only Nutri-Cosmetic with patented Swiss plant stem cell extract Skin has complex multi-dimensional needs – therefore, need a sophisticated & advance skin nutricosmetic Uses NEW & more powerful multi-functional ingredients with special properties and functions Integrating the best from Japan, France & Switzerland – a product of LiveLife Biosciences A.G., Zurich NEW Multi-Functional Ingredients 1000 times more potent than conventional Vitamin E in inhibiting lipid peroxidation 40 times higher oxygen quenching rate than beta-carotene Stimulate biosynthesis of elastin & collagen Improve moisturization Protect & revive skin stem cells

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What are Stem Cells? Two types of Stem Cells in Human Body Embryonic: is pluripotent (i.e. has the capacity to differentiate into other cell types eg. muscle, blood, nerve tissue etc.) Adult: to regulate, repair and rejuvenate tissues (can only differentiate into their own cell types) Skin Stem Cells Found in basal layer of the epidermis Re-organize, repair & replenish our skin with fresh, healthy new cells Responsible for maintaining youthful skin Ratio of skin stem cells to skin cells is 1:10,000 Have the ability to create new skin cells and regenerate the skin for a lifetime, theoretically Age and environmental factors cause them to function less efficiently They then have a limited life expectancy because of: stress poor diet UV rays Ozone Smoking

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This accelerates the depletion of skin stem cells, reduce their regenerative ability & cause DNA damage, telomere shortening and oxidative stress Therefore, skin stem cell activity begins to slow down with age & environmental damage When stem cells become inactive, skin rejuvenation stops However, under the right stimulus, stem cell activity could be jump-started to re-initiate skin rejuvenation – the inspiration The Swiss Breakthrough Swiss scientists discovered a way to rejuvenate skin stem cells Successfully cultivated & harvested a novel stem cell extract, from an almost extinct fruit plant species in Switzerland This stem cell extract from plants is rich in epigenetic (growth) factors and metabolites – nutrients for our skin stem cells – thus strengthening and prolonging the life of our skin stem cells – the solution MIREICA nutri-peau Advanced Comprehensive & Sophisticated Natural 4 proprietary formulations The difference with other skin supplements Beyond collagen Beyond anti-oxidants New advanced ingredients for skin health Scientific breakthrough: revive skin stem cells for skin rejuvenation

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NutriGene® – skin blueprints Plant stem cell extract UV protective ingredients Lipids Amino acids NutriGene® – skin blueprints – What it does – Stimulates or jump-starts skin stem cell activity Healthy skin stem cells  ‘Perfect’ skin cells  radiant, youthful, beautiful skin 2. OptaCell® – Brightening & hydration booster Plant ceramide complex from Japanese technology* Lipids *Prof. Igarashi – Graduate School of Pharmaceutical Sciences Hokkaido University OptaCell® – What it does – Improves lipids synthesis, replenish essential skin lipids, restore lipidic balance for optimal barrier function Improves water retention & moisturizing function Brightening effect – lightening of pigmentation

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3. EnviroShield® – skin defense shield Astaxanthin: extracted and purified from specific algae with natural UV defense properties Vitamin C EnviroShield® – What it does – Strengthens internal defense against sun, environmental and oxidative stresses Regulates melanin production, pigmentation and age spots Protects skin collagen against oxidative cross-linking & degradation of new collagen 4. Micro-BioNutrients TM – Skin building blocks Marine proteins and elastin peptides (in same ratio as in dermis) Vitamins C Omega 3 (DHA) Amino Acids Micro-BioNutrientsTM -What it does- Stimulate biosynthesis of dermis Enhance production of natural collagen & elastin Improves skin elasticity, firmness, smoothness and tone Significantly reduces the appearance of fine lines and wrinkles

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How long before I see results? First month: start experiencing better skin hydration, smoothness and radiance After 2 – 3 months: supple, elastic, less pigmentation, brighter, more even tone and wrinkle reduction Regular use: revived skin stem cells rejuvenates skin, beautiful skin, perfecting from within How do I take Mireica? First empty sachet content into a glass & then add cold water or juice Stir lightly & drink immediately Best taken on empty stomach first thing in the morning or just before bedtime. Is it safe for long-term? Ingredients are natural, derived from plant and marine sources, and are known and regarded as safe for long term use in Japan, Europe and Switzerland No known side effects

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In Conclusion MIREICA A Most Advanced Anti-Aging Nutricosmetic World’s first and Only With Plant Stem Cell Extract