Fibrocystic breast disease1

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Fibrocystic breast disease

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Findings in women seeking evaluation of apparent breast lump Fibrocystic breast changes 40% No disease 30% Fibroadenoma 7% Other benign mammary dysplasias and neoplasms 13% Breast cancer 10% Fibrocystic breast changes or fibrocystic breast disease is a condition of breast tissue affecting an estimated 30-60% of women. It is characterized by noncancerous breast lumps in the breast which can sometimes cause discomfort, often periodically related to hormonal influences from the menstrual cycle Fibrocystic definition

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the condition is called diffuse cystic mastopathy, or, if there is epithelial proliferation, fibrosclerosis of breast. Older names for this condition include fibrocystic mastopathy and mammary dysplasia Other name

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it is known that they are tied to ovarian hormone levels, as the condition usually subsides after menopause. It is also related to the menstrual cycle and to dietary conditions N.B ; The incidence is lower in women taking birth control, possibly because of the regulation of hormone levels causes

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*family history, *a high fat diet, *excess caffeine intake Risk factors

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The lumps are most often found in the upper, outer sections of the breast (nearest to the armpit). *characterised by the appearance of fibrous tissue and a lumpy. *These lumps are smooth with defined edges, and are usually free-moving in regard to adjacent structures *The bumps can sometimes be obscured by irregularities in the breast APPERANCE OF LUMPS

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Symptoms follow a periodic trend tied closely to the menstrual cycle. These symptoms, which range from mild to severe tend to peak immediately before each period and decrease afterwards. At peak, breasts may feel full and swollen Common symptoms include discomfort, fullness, heaviness, swelling, pain , tendernce and itchy in one or both breasts. Some women may also experience a non-bloody discharge in one or both nipples symptom

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Fibrocystic Changes Nonproliferative Change Proliferative Change Sclerosing Adenosis

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N.B ; A woman who has fibrocystic disease isn't necessarily at risk for developing breast cancer, unless atypical hyperplasia (abnormal cells in the breast lobules and ducts) is present

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Comments: Some of the larger cysts in fibrocystic disease may have a bluish appearance from outside (blue-domed cysts). The cyst lining is flattened or absent in some cases. In the center of this image, cysts are lined by apocrine epithelium. Note the focus of adenosis above it

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:CommentsApocrine metaplasia is a frequent finding in fibrocystic disease. The lining cells have abundant eosinophilic granular cytoplasm, prominent nucleolus and apocrine snouts. Immunostain for GCDFP-15 is strongly positive. Presence of cytologic atypia in apocrine metaplasia is not a risk factor for carcinoma

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lobular hyperplasia, adenosis, simple type. Sclerosing Adenosis

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Usual type epithelial hyperplasia

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This patient developed severe fibrosis

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Diagnosis This condition is often easily diagnosed by a doctor, though it may require a biopsy of the affected area. Mammography does not often work for diagnosis of CCM, as the breast tissue is often too dense to allow for thorough examination. Aspiration with a very fine needle is used to drain fluid from larger cysts

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Prognosis There are usually no adverse side effects to this condition. In almost all cases it subsides after menopause. A possible complication arises through the fact that cancerous tumors may be more difficult to detect in women with fibrocystic changes. This condition does not seem to lead to increased breast cancer risk

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عمل الطالبات أفنان العتيبي رحمة الثبيتي نادية السفياني نورة الزهراني هند العتيبي

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