ND NIVW 202007 FINAL 2 5

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Preventing Influenza through Vaccination: Patients and Providers : 

Preventing Influenza through Vaccination: Patients and Providers Jeanne M. Santoli, MD, MPH National Center for Immunization and Respiratory Diseases November 26, 2007

Overview : 

Overview Burden of disease Highlights of the 2007 ACIP recommendations Recommended groups Recommendations for children Vaccination of healthcare providers (HCP) Timing of vaccination National Influenza Vaccination Week

Annual Burden of Disease : 

Annual Burden of Disease Infected – 15-60 million Total deaths – 36,000 Total hospitalizations – 200,000 Pediatric deaths – 56 - 154 Pediatric hospitalizations 20,000

Slide 4: 

incapable of being determined in advance whether by observation, experience or reason; irregular; as in “everything about influenza is unpredictable” Un-pre-dict-a-ble (adjective)

Slide 5: 

2007 ACIP Recommendations for the Control and Prevention of Influenza

Highlights of the 2007 Recommendations : 

Highlights of the 2007 Recommendations No change in the groups recommended for vaccination Change in recommendations for children ages 6 months to <9 years who received a single dose during their first (previous) year of vaccination New: recommended to receive 2 doses in second year of vaccination LAIV recommendations expanded to include healthy 2-5 year olds who don′t have a history of asthma or wheezing* Emphasize the importance of vaccinating healthcare providers Emphasize the need to continue vaccination beyond the traditional months of October and November *CDC. MMWR November 23, 2007. 56: 1217-1219

Recommended Groups, I : 

Recommended Groups, I Efforts should target these groups : Children aged 6–59 months All persons aged >50 years Household contacts (including children) and caregivers of infants who are younger than 6 months old Children and adolescents on long-term aspirin therapy Pregnant women Adults and children who have chronic diseases Immunosuppressed adults and children Adults and children with a condition that can compromise respiratory function, handling of respiratory secretions, or increase the risk for aspiration Residents of nursing homes and other chronic-care facilities.

Recommended Groups, II : 

Recommended Groups, II In addition, to prevent transmission to persons such as those at increased risk of complications, the following groups are recommended for annual influenza: Healthcare providers Healthy household contacts (including children) and caregivers of: Children 6-59 months of age, adults >50 years Children and adults with medical conditions that put them at increased risk for severe complications from influenza

Estimated Size of ACIP Recommended Groups : 

Estimated Size of ACIP Recommended Groups

Emphasizing the Permissive Component of the Seasonal Recommendations : 

Emphasizing the Permissive Component of the Seasonal Recommendations Vaccination is recommended for persons, including school-age children, who want to reduce the likelihood of becoming ill with influenza or transmitting influenza to others should they become infected.

Highlights of the 2007 Recommendations : 

Highlights of the 2007 Recommendations No change in the groups recommended for vaccination Change in recommendations for children ages 6 months to <9 years who received a single dose during their first (previous) year of vaccination New: recommended to receive 2 doses in second year of vaccination LAIV recommendations expanded to include healthy 2-5 year olds who don't have a history of asthma or wheezing* Emphasize the importance of vaccinating healthcare providers Emphasize the need to continue vaccination beyond the traditional months of October and November *CDC. MMWR November 23, 2007. 56: 1217-1219

Recommendations for Childhood Vaccination : 

Recommendations for Childhood Vaccination Longstanding recommendation: first time vaccinees less than 9 years of age should receive two doses, spaced 4 weeks apart Those who only received one dose in the first year should receive only one dose the following year New data suggests that these children have less benefit Beginning with 2007-08 season: Children who didn’t receive two doses during their initial year of vaccination, should receive two doses the next year.

Influenza Vaccination Coverage Among Children 6-23 Months of Age, National Immunization Survey, 2003-06 : 

Influenza Vaccination Coverage Among Children 6-23 Months of Age, National Immunization Survey, 2003-06 First season of “vaccinate all 6-23 month olds” recommendation

How did North Dakota’s children fare in 2005-06? : 

How did North Dakota’s children fare in 2005-06? 38.5% of 6-23 month old children received 1 or more doses of vaccine 4.2% increase from 2004-2005* 32.3 % of fully vaccinated 6-23 month olds 7.9% increase from 2004-2005* Sources: CDC. MMWR September 21, 2007. 56: 959-963 * CDC. MMWR October 6, 2006. 55(39): 1062-1065

Highlights of the 2007 Recommendations : 

Highlights of the 2007 Recommendations No change in the groups recommended for vaccination Change in recommendations for children ages 6 months to <9 years who received a single dose during their first (previous) year of vaccination New: recommended to receive 2 doses in second year of vaccination LAIV recommendations expanded to include healthy 2-5 year olds who don't have a history of asthma or wheezing* Emphasize the importance of vaccinating healthcare providers Emphasize the need to continue vaccination beyond the traditional months of October and November *CDC. MMWR November 23, 2007. 56: 1217-1219

Slide 16: 

LAIV Recommendation Expanded On September 19, 2007 US FDA licensed the use of LAIV for healthy children ages 2-4 years (24-59 months). On October 24, 2007 the Advisory Committee on Immunization Practices (ACIP) expand the recommendation of LAIV to include healthy children from 2 to 5 years of age (24-59 months) who don′t have a history of asthma or wheezing.* Previously, recommendations were for healthy people ages 5-49 years who are not pregnant. “Healthy” indicates people who do not have an underlying medical condition that predisposes them to influenza complications. *CDC. MMWR November 23, 2007. 56: 1217-1219

Highlights of the 2007 Recommendations : 

Highlights of the 2007 Recommendations No change in the groups recommended for vaccination Change in recommendations for children ages 6 months to <9 years who received a single dose during their first (previous) year of vaccination New: recommended to receive 2 doses in second year of vaccination LAIV recommendations expanded to include healthy 2-5 year olds who don't have a history of asthma or wheezing* Emphasize the importance of vaccinating healthcare providers Emphasize the need to continue vaccination beyond the traditional months of October and November *CDC. MMWR November 23, 2007. 56: 1217-1219

Self-Reported Influenza Vaccination Coverage Levels Among Selected US Adult Populations 1989-2005, National Health Interview Survey : 

Self-Reported Influenza Vaccination Coverage Levels Among Selected US Adult Populations 1989-2005, National Health Interview Survey Vaccine shortage: 2004-05 season National Health Interview Survey data available at: http://www.cdc.gov/nip/coverage/default.htm#NHIS

Why is it so important to vaccinate healthcare providers (HCP)? : 

Why is it so important to vaccinate healthcare providers (HCP)? HCP contact infected materials from patients HCP have direct contact with HR patients every day Transmission of disease seen in many different healthcare settings HCP immunity is key to infection prevention and control programs

Slide 20: 

...unvaccinated healthcare workers can be the index case for influenza in a facility, potentially posing a threat to high-risk patients and other workers. May 2004,32(3)

Which HCP are recommended for vaccination? : 

Which HCP are recommended for vaccination? Group includes physicians, nurses, nursing assistants, therapists, technicians, pharmacists, laboratory personnel, students and trainees, clerical, dietary, housekeeping, maintenance, and volunteers Settings include hospitals, nursing homes, skilled nursing facilities, physicians’ offices, urgent care centers, and outpatient clinics, and to persons who provide home health care and emergency medical services

Why don’t healthcare providers get vaccinated? : 

Why don’t healthcare providers get vaccinated? There are many reason, including: Insufficient time, inconvenient Belief that vaccine doesn’t work Belief that you can get the flu from the flu vaccine Concerns about adverse events Perception of low risk Misperceptions about risk of transmission to HR patients Avoidance of all medications Fear of needles

Influenza Vaccine Benefits Healthcare Providers : 

Influenza Vaccine Benefits Healthcare Providers 28% fewer lost work days due to respiratory infections 28% fewer days HCP felt unable to work Lower incidence of influenza, 1.7%; compared to controls 13.4% Fewer respiratory illnesses than controls; 28.7 vs. 40.6 per 100 persons Fewer days of lost work than control groups; 9.9 vs. 21.1 per 100 persons

Strategies for Improving HCP Vaccination Rates : 

Strategies for Improving HCP Vaccination Rates Education and campaigns Improved access to vaccine Vaccination clinics Mobile carts Access during all work shifts Institutional role models Measurement and feedback

Support from Professional Groups : 

Support from Professional Groups

Joint Commission on Accreditation of Healthcare Organizations (JCAHO)1 New standard, effective 1/1/07: Influenza immunization offered to staff and licensed independent practitioners. Infectious Diseases Society of America  (IDSA)2 January 2007- Recommendation that U.S. adopt policy to include mandatory annual influenza vaccination among healthcare workers American College of Physicians (ACP)3 October 2007 - Recommendation that annual influenza vaccine should be required for every health care worker with direct patient care activities. 1http://www.jcrinc.com/26813/newsletters/12882/, accessed 11/11/07; 2Pandemic and Seasonal Influenza Principles for U.S. Action, January 2007; 3http://www.acponline.org/college/pressroom/hcw.htm, accessed 11/13/07.

What other vaccines do healthcare providers need? : 

What other vaccines do healthcare providers need? Hepatitis B MMR Varicella Td/Tdap Influenza

Healthcare ProviderVaccination Recommendations : 

Healthcare ProviderVaccination Recommendations SOURCE: http://www.immunize.org/catg.d/p2017.pdf

Highlights of the 2007 Recommendations : 

Highlights of the 2007 Recommendations No change in the groups recommended for vaccination Change in recommendations for children ages 6 months to <9 years who received a single dose during their first (previous) year of vaccination New: recommended to receive 2 doses in second year of vaccination LAIV recommendations expanded to include healthy 2-5 year olds who don't have a history of asthma or wheezing* Emphasize the importance of vaccinating healthcare providers Emphasize the need to continue vaccination beyond the traditional months of October and November *CDC. MMWR November 23, 2007. 56: 1217-1219

Month of Peak Influenza Activity, US 1976-2006 : 

Month of Peak Influenza Activity, US 1976-2006 US WHO Collaborating Centers (CDC, unpublished data). Peak week defined as week with greatest % of positive specimens for influenza on basis of three-week moving average.

Timing of Vaccination : 

Timing of Vaccination Prior recommendations—”optimal” timing for vaccination October and November US Surveillance data indicate that disease peaks in February or later in the majority of seasons Timing of vaccine production, distribution challenging for many of the past seven seasons ACIP recommendations this year emphasize extending vaccination into December, January and beyond Providers should be alert to potential vaccination opportunities during all healthcare encounters Organized campaigns should be scheduled through December and later if feasible

What is National Influenza Vaccination Week (NIVW)? : 

What is National Influenza Vaccination Week (NIVW)? Goal: Annual event to help raise awareness of the importance of influenza vaccination and the importance of continuing vaccination throughout November and beyond November 26-December 2, 2007

Slide 33: 

Why are we doing NIVW?

Not reaching goals for vaccinating high risk persons. : 

Not reaching goals for vaccinating high risk persons.

Self-Reported Influenza Vaccination Coverage Levels Among Selected US Adult Populations 1989-2005, National Health Interview Survey : 

Self-Reported Influenza Vaccination Coverage Levels Among Selected US Adult Populations 1989-2005, National Health Interview Survey Vaccine shortage: 2004-05 season National Health Interview Survey data available at: http://www.cdc.gov/nip/coverage/default.htm#NHIS

Influenza Vaccination Coverage among Children 6-23 Months of Age, National Immunization Survey, 2003-06 : 

Influenza Vaccination Coverage among Children 6-23 Months of Age, National Immunization Survey, 2003-06 First season of “vaccinate all 6-23 month olds” recommendation

Disease typically peaks in February or later and influenza can come to a community more than once. : 

Disease typically peaks in February or later and influenza can come to a community more than once.

Month of Peak Influenza Activity, US 1976-2006 : 

Month of Peak Influenza Activity, US 1976-2006 US WHO Collaborating Centers (CDC, unpublished data). Peak week defined as week with greatest % of positive specimens for influenza on basis of three-week moving average.

Given current production capacity, vaccine continues to be produced and distributed during the fall. : 

Given current production capacity, vaccine continues to be produced and distributed during the fall. Photo Source: sanofi pasteur

Cumulative Monthly Influenza Vaccine Distribution(*Through 10/26/2007 *) : 

Cumulative Monthly Influenza Vaccine Distribution(*Through 10/26/2007 *) Doses (Millions) 83 81.2 102.5 98.1 * *

Many people are unaware that vaccination after Thanksgiving can be protective. : 

Many people are unaware that vaccination after Thanksgiving can be protective.

Slide 42: 

Estimated Number of Persons Reporting Vaccination for Influenza by Month–National Health Interview Survey, United States, 2005-06 and 2006-07 Influenza Seasons Source: CDC. MMWR November 23, 2007. 56: 1216-1217 † Estimates are based on 1-month sampling weights. § Persons aged > 6 months for whom month of influenza vaccination was reported in interviews conducted in March 2007. ¶ Persons aged > 6 months for whom month of influenza vaccination was reported in interviews conducted in March 2006.

Influenza Materialswww.cdc.gov/flu : 

Influenza Materialswww.cdc.gov/flu Posters Fact Sheets Flyers Media Toolkit Ecards PSAs Podcasts NIVW Activity Calendar Provider Education Patient Education

Summing Up . . . : 

Summing Up . . . Influenza is a serious disease, affecting many children, adolescents, and adults Recommendation highlights this year include expanded use of second dose for children < 9; continued emphasis on vaccination of HCP; and new guidance on the timing of vaccination National Influenza Vaccination Week (NIVW) is aimed at increasing awareness of the seriousness of influenza, the benefits of vaccination, and the need to continue vaccination beyond October/November

Immunization Contact Information : 

Immunization Contact Information Hotline: 800.CDC.INFO 800-232-4636 Email: nipinfo@cdc.gov Website: www.cdc.gov/vaccines www.cdc.gov/flu

Questions? : 

Questions?