TB ppt

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By: puneetraj08 (35 month(s) ago)

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PulmonaryTuberculosis : 

PulmonaryTuberculosis

Primary PulmonaryTuberculosis : 

Primary PulmonaryTuberculosis

1° Pulmonary Tuberculosis : 

1° Pulmonary Tuberculosis Patterns Pneumonia Adenopathy Atelectasis Pleural effusion

Primary TuberculosisPneumonia : 

Primary TuberculosisPneumonia Upper lobes affected slightly more than lower Pneumonia common Cavitation is rare Lobar pneumonia almost always associated with lymphadenopathy Infiltrate + ipsilateral adenopathy–think TB

Primary TuberculosisAdenopathy : 

Primary TuberculosisAdenopathy Unilateral hilar and/or paratracheal Usually right-sided Rarely bilateral Differentiates 1° from 2°—does not occur in postprimary TB Adenopathy much more common in children

Primary TuberculosisAtelectasis : 

Primary TuberculosisAtelectasis Classically affects anterior segments of upper lobes, or Medial segment of the RML

Primary TuberculosisPleural Manisfestations : 

Primary TuberculosisPleural Manisfestations Effusion as a manifestation of 1° TB more common in adults than children

Primary TuberculosisGeneral : 

Primary TuberculosisGeneral Calcification in 1° complex is relatively rare Few patients with 1° TB have clinical manifestations

Postprimary Tuberculosis Reactivation TB : 

Postprimary Tuberculosis Reactivation TB

Reactivation TBGeneral : 

Reactivation TBGeneral Most cases in adults occur as reactivation of 1° focus of infection acquired in childhood Caseous necrosis and tubercle are pathologic hallmarks of post 1° TB Tubercle=accumulations of mononuclear macrophages, Langhan’s giant cells surrounded by lymphocytes/fibroblasts

Reactivation TBGeneral : 

Reactivation TBGeneral Healing occurs with fibrosis and contraction Calcification is rarer than in 1° Limited mainly to apical and posterior segments of upper lobes and superior segments of lower lobe

Reactivation TBPatterns : 

Reactivation TBPatterns Pneumonia Cavity formation Transbronchial spread Bronchiectasis Bronchostenosis Pleural disease Tuberculoma Bone involvement

Reactivation TBPatterns : 

Reactivation TBPatterns Affects apical or posterior segments of upper lobes or superior segments of lower lobes Bilateral upper lobe disease is very common May present as pneumonia Cavitation may result Cavity is usually thin-walled, smooth on inner margin with no air-fluid level

Reactivation TBPatterns : 

Reactivation TBPatterns Transbronchial spread may occur—from one upper lobe to opposite lower Bronchiectasis—usually asymptomatic Bronchostenosis due to fibrosis and stricture Fibrosis may cause distortion of a bronchus and atelectasis many years after initial infection=“middle lobe syndrome”

Reactivation TBPatterns : 

Reactivation TBPatterns Pleural effusion in postprimary TB Almost always means direct spread of disease in to pleural cavity Should be regarded as an empyema Carries a graver prognosis than effusion of 1° form Direct extension into ribs or sternoclavicular joints is uncommon

Reactivation TBPatterns : 

Reactivation TBPatterns Solitary pulmonary nodule Tuberculoma May occur in either 1° or postprimary disease Round or oval lesions with small, discrete shadows in immediate vicinity of lesion=“satellite” lesion

MiliaryTuberculosis : 

MiliaryTuberculosis

Miliary TuberculosisGeneral : 

Miliary TuberculosisGeneral Hematogenous dissemination of bacilli common in 1° TB but clinically evident miliary TB rarely occurs May not manifest itself for many years after infection

Miliary TuberculosisClinical : 

Miliary TuberculosisClinical Older men, Blacks and pregnant women susceptible Onset is insidious Fever, chills, night sweats are common Takes weeks between time of dissemination and radiographic appearance of disease

Miliary TuberculosisNatural History : 

Miliary TuberculosisNatural History When first visible, measure about 1 mm in size Frequently missed on first films Can grow to 2-3mm if left untreated When treated, clearing is rapid Miliary TB does NOT heal with calcification

Calcification in TB3 Funny Names : 

Calcification in TB3 Funny Names Ghon lesion=calcified granuloma Ranke complex=Ghon lesion+calcified lymph node Simon focus=healed site of 1° infection at lung apex

TB and Other Diseases : 

TB and Other Diseases Occurs with a higher incidence in sarcoid-especially if rx with steroids Associated with silicosis Associated with HIV infection No relationship with bronchogenic Ca

TB and AIDS : 

TB and AIDS Mycobacterium avium-intracellulare (MAI) is more common than TB TB in AIDS looks like 1° form Hilar and mediastinal adenopathy common Cavitation less common No predilection for apices

TB:The Question of Activity : 

TB:The Question of Activity Only serial images with no change can suggest lack of activity–2 years In presence of cavities, activity must be determined clinically

TuberculosisAncient Remedies : 

TuberculosisAncient Remedies Rest Theory “Ping-pong ball” plumbage Paraffin plumbage Oleothorax Pneumothorax and pneumoperitoneum Thoracoplasty