logging in or signing up Stress and Disease aSGuest1260 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 1294 Category: Science & Tech.. License: All Rights Reserved Like it (0) Dislike it (0) Added: October 18, 2008 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... By: pgstud (32 month(s) ago) This Presentation is really a good one. It is very concise & more informative. I would like to get the permission to download it. Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Stress and Disease : Stress and Disease Hans Selye: Father of Stress Research : Hans Selye: Father of Stress Research Austrian-born, Canadian physician Injected ovarian extracts into rats attempting to identify new sex hormone Discovered triad of stress effects Stress Effects Triad : Stress Effects Triad Enlargement of Adrenal Cortex Atrophy of thymus, other lymphatics Bleeding ulcers of stomach, duodenum Stress : Stress Non-specific state of physical and psychological arousal to stressor Stressor : Stressor Any stimulus that triggers stress response General Adaptation Syndrome : General Adaptation Syndrome ALARM RESISTANCE ADAPTATION General Adaptation Syndrome : DISEASE General Adaptation Syndrome ALARM RESISTANCE EXHAUSTION Homeostasis : Homeostasis Dynamic Steady State Slide 9: Stressor Central Nervous System Psychological Response Hypothalamus Sympathetic Nervous System Anterior Pituitary Adrenal Cortex SNS Neurons Adrenal Medulla Immune System CRF ACTH Norepi Norepi Epi Cortisol Slide 10: CNS Hypothalamus Anterior Pituitary Adrenal Cortex Immune System CRF ACTH Cortisol + + Macrophages - + Cytokines Stress Response : Stress Response Psychoneuroimmunologic Alpha-Beta Effects : Alpha-Beta Effects Catecholamine Effects : Catecholamine Effects Brain Increased blood flow Increased glucose metabolism Cardiovascular System Increased heart rate, force of contraction Peripheral vasoconstriction Central vasodilation Catecholamine Effects : Catecholamine Effects Respiratory System Bronchodilation Decreased work of breathing Increased oxygen supply Liver Increased glycogenolysis Increased gluconeogenesis Decreased glycogenesis Catecholamine Effects : Catecholamine Effects Skeletal Muscle Increased glycogenolysis Increased dilation of blood vessels Adipose Tissue Increased lipolysis Increased fatty acids, glycerol Catecholamine Effects : Catecholamine Effects Skin Decreased blood flow GI, GU Tracts Decreased blood flow Decreased protein synthesis Catecholamine Effects : Catecholamine Effects Skeleton Decreased glucose uptake, use Lymphoid Tissue Increased protein breakdown Cortisol Effects : Cortisol Effects Carbohydrate Metabolism Increased gluconeogenesis Decreased peripheral glucose uptake Increased blood glucose levels Cortisol Effects : Cortisol Effects Protein Metabolism Increased protein breakdown in muscle, lymphoid tissue, muscle, skin, bone Increased blood amino acid levels Decreased immunoglobulin levels Increased synthesis of clotting factors, plasma proteins in liver Cortisol Effects : Cortisol Effects Lipid Metabolism Increased lipolysis in extremities Lipogenesis in face, trunk Cortisol Effects : Cortisol Effects Antinflammatory Effects Decreased immunoglobulin production Decreased lymphocytes, macrophages, eosinophils Decreased interleukin production Decreased cell-mediated immunity Decreased inflammatory response Cortisol Effects : Cortisol Effects GI Tract Increased secretions Connective Tissue Decreased fibroblast proliferation Bone Decreased bone formation Other Hormones : Other Hormones Beta-endorphins, increase = Decreased pain sensitivity; increased sense of well-being Growth hormone, increase = Increased utilization of protein, lipid, carbohydrate Testosterone, decrease Prolactin, increase Stress Response: Up Side : Stress Response: Up Side Elevated blood glucose, lipids, amino acids Elevated blood oxygen Shifting of blood flow to heart, lungs, brain, skeletal muscles Shifting of blood flow away from skin, gut, kidney Stress Response: Down Side : Stress Response: Down Side Elevated blood glucose = hyperglycemia, diuresis Elevated blood lipids = atherosclerosis Depressed immune response = increased infections, poor healing, allergies, autoimmune diseases Increased GI secretions, decreased motility = ulcers Increased skeletal muscle blood flow, metabolism = tension headaches, back aches Decreased testosterone = impotence Increased CNS metabolism = fatigue, depression, insomnia You do not have the permission to view this presentation. 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Stress and Disease aSGuest1260 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 1294 Category: Science & Tech.. License: All Rights Reserved Like it (0) Dislike it (0) Added: October 18, 2008 This Presentation is Public Favorites: 0 Presentation Description No description available. Comments Posting comment... By: pgstud (32 month(s) ago) This Presentation is really a good one. It is very concise & more informative. I would like to get the permission to download it. Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Stress and Disease : Stress and Disease Hans Selye: Father of Stress Research : Hans Selye: Father of Stress Research Austrian-born, Canadian physician Injected ovarian extracts into rats attempting to identify new sex hormone Discovered triad of stress effects Stress Effects Triad : Stress Effects Triad Enlargement of Adrenal Cortex Atrophy of thymus, other lymphatics Bleeding ulcers of stomach, duodenum Stress : Stress Non-specific state of physical and psychological arousal to stressor Stressor : Stressor Any stimulus that triggers stress response General Adaptation Syndrome : General Adaptation Syndrome ALARM RESISTANCE ADAPTATION General Adaptation Syndrome : DISEASE General Adaptation Syndrome ALARM RESISTANCE EXHAUSTION Homeostasis : Homeostasis Dynamic Steady State Slide 9: Stressor Central Nervous System Psychological Response Hypothalamus Sympathetic Nervous System Anterior Pituitary Adrenal Cortex SNS Neurons Adrenal Medulla Immune System CRF ACTH Norepi Norepi Epi Cortisol Slide 10: CNS Hypothalamus Anterior Pituitary Adrenal Cortex Immune System CRF ACTH Cortisol + + Macrophages - + Cytokines Stress Response : Stress Response Psychoneuroimmunologic Alpha-Beta Effects : Alpha-Beta Effects Catecholamine Effects : Catecholamine Effects Brain Increased blood flow Increased glucose metabolism Cardiovascular System Increased heart rate, force of contraction Peripheral vasoconstriction Central vasodilation Catecholamine Effects : Catecholamine Effects Respiratory System Bronchodilation Decreased work of breathing Increased oxygen supply Liver Increased glycogenolysis Increased gluconeogenesis Decreased glycogenesis Catecholamine Effects : Catecholamine Effects Skeletal Muscle Increased glycogenolysis Increased dilation of blood vessels Adipose Tissue Increased lipolysis Increased fatty acids, glycerol Catecholamine Effects : Catecholamine Effects Skin Decreased blood flow GI, GU Tracts Decreased blood flow Decreased protein synthesis Catecholamine Effects : Catecholamine Effects Skeleton Decreased glucose uptake, use Lymphoid Tissue Increased protein breakdown Cortisol Effects : Cortisol Effects Carbohydrate Metabolism Increased gluconeogenesis Decreased peripheral glucose uptake Increased blood glucose levels Cortisol Effects : Cortisol Effects Protein Metabolism Increased protein breakdown in muscle, lymphoid tissue, muscle, skin, bone Increased blood amino acid levels Decreased immunoglobulin levels Increased synthesis of clotting factors, plasma proteins in liver Cortisol Effects : Cortisol Effects Lipid Metabolism Increased lipolysis in extremities Lipogenesis in face, trunk Cortisol Effects : Cortisol Effects Antinflammatory Effects Decreased immunoglobulin production Decreased lymphocytes, macrophages, eosinophils Decreased interleukin production Decreased cell-mediated immunity Decreased inflammatory response Cortisol Effects : Cortisol Effects GI Tract Increased secretions Connective Tissue Decreased fibroblast proliferation Bone Decreased bone formation Other Hormones : Other Hormones Beta-endorphins, increase = Decreased pain sensitivity; increased sense of well-being Growth hormone, increase = Increased utilization of protein, lipid, carbohydrate Testosterone, decrease Prolactin, increase Stress Response: Up Side : Stress Response: Up Side Elevated blood glucose, lipids, amino acids Elevated blood oxygen Shifting of blood flow to heart, lungs, brain, skeletal muscles Shifting of blood flow away from skin, gut, kidney Stress Response: Down Side : Stress Response: Down Side Elevated blood glucose = hyperglycemia, diuresis Elevated blood lipids = atherosclerosis Depressed immune response = increased infections, poor healing, allergies, autoimmune diseases Increased GI secretions, decreased motility = ulcers Increased skeletal muscle blood flow, metabolism = tension headaches, back aches Decreased testosterone = impotence Increased CNS metabolism = fatigue, depression, insomnia