logging in or signing up Pharmacology aSGuest1246 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 656 Category: Science & Tech.. License: All Rights Reserved Like it (0) Dislike it (0) Added: October 18, 2008 This Presentation is Public Favorites: 1 Presentation Description No description available. Comments Posting comment... By: Jaimini (42 month(s) ago) Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Pharmacology : Pharmacology Drugs used to treat: Asthma Rhinitis & Cough Topics : Topics Bronchodilators Methylxanthines Anticholinergics Anti-inflammatory Agents Leukotriene Antagonists Mast cell stabilizers Decongestants Antihistamines Antitussives Expectorants & mucolytics Asthma : Asthma Inflammatory response to allergen Antibody binds with & ruptures mast cells Releases histamine, prostaglandins, leukotrienes Two primary issues Bronchoconstriction Inflammation (mucous production) Approaches to Treatment : Approaches to Treatment Relax bronchial smooth muscle ß2 agonists methylxanthines anticholinergics Inhibit release of mediators Glucocorticoids Mast cell stabilizers Block affects of mediators Leukotriene antagonists Bronchodilators : Bronchodilators Antiinflammatory Agents : Antiinflammatory Agents Colds and Allergies : Colds and Allergies Nasal Inflammation Vasodilation & engorgement Itching, redness, rhinorrhea Mast/basophil degranulation Nasal Decongestants : Nasal Decongestants congestion via vasodilation Alpha1 stimulation Topical administration phenylephrine (Neo-Synephrine®) pseudoephedrine (Sudafed®, Actifed®) A moment of silence for: phenylpropanolamine (AlkaSeltzer Cold®, Contact®, Allerest®) Antihistamines : Antihistamines H1 receptors Vasodilation Increased capillary permeability Bronchoconstriction H2 receptors Increase gastric acid secretion (Zantac®), etc) Other histamine receptors Sedation Antihistamine Agents : Antihistamine Agents First generation Sedation chlorpheniramine (Chlor-Trimeton®) diphenhydramine (Benadry®) clemastine (Tavist®) promethazine (Phergan®) Second generation No sedation blood-brain barrier Sniff, sniff: terfenadine (Seldane®) fexofenadine (Allegra®) cetirizine (Zyrtec®) loratadine (Claritin®) Cough Suppressants : Cough Suppressants Antitussives Decrease cough reflex Opioids codeine & hydrocodone Non-opioids dextromethorphan benzonatate (Tessalon®) Expectorants guaifenesin may work others are doubtful Mucolytics Decreases viscocity acetlycysteine (Mucomyst®) hypertonic saline You do not have the permission to view this presentation. In order to view it, please contact the author of the presentation.
Pharmacology aSGuest1246 Download Post to : URL : Related Presentations : Share Add to Flag Embed Email Send to Blogs and Networks Add to Channel Uploaded from authorPOINT lite Insert YouTube videos in PowerPont slides with aS Desktop Copy embed code: (To copy code, click on the text box) Embed: URL: Thumbnail: WordPress Embed Customize Embed The presentation is successfully added In Your Favorites. Views: 656 Category: Science & Tech.. License: All Rights Reserved Like it (0) Dislike it (0) Added: October 18, 2008 This Presentation is Public Favorites: 1 Presentation Description No description available. Comments Posting comment... By: Jaimini (42 month(s) ago) Saving..... Post Reply Close Saving..... Edit Comment Close Premium member Presentation Transcript Pharmacology : Pharmacology Drugs used to treat: Asthma Rhinitis & Cough Topics : Topics Bronchodilators Methylxanthines Anticholinergics Anti-inflammatory Agents Leukotriene Antagonists Mast cell stabilizers Decongestants Antihistamines Antitussives Expectorants & mucolytics Asthma : Asthma Inflammatory response to allergen Antibody binds with & ruptures mast cells Releases histamine, prostaglandins, leukotrienes Two primary issues Bronchoconstriction Inflammation (mucous production) Approaches to Treatment : Approaches to Treatment Relax bronchial smooth muscle ß2 agonists methylxanthines anticholinergics Inhibit release of mediators Glucocorticoids Mast cell stabilizers Block affects of mediators Leukotriene antagonists Bronchodilators : Bronchodilators Antiinflammatory Agents : Antiinflammatory Agents Colds and Allergies : Colds and Allergies Nasal Inflammation Vasodilation & engorgement Itching, redness, rhinorrhea Mast/basophil degranulation Nasal Decongestants : Nasal Decongestants congestion via vasodilation Alpha1 stimulation Topical administration phenylephrine (Neo-Synephrine®) pseudoephedrine (Sudafed®, Actifed®) A moment of silence for: phenylpropanolamine (AlkaSeltzer Cold®, Contact®, Allerest®) Antihistamines : Antihistamines H1 receptors Vasodilation Increased capillary permeability Bronchoconstriction H2 receptors Increase gastric acid secretion (Zantac®), etc) Other histamine receptors Sedation Antihistamine Agents : Antihistamine Agents First generation Sedation chlorpheniramine (Chlor-Trimeton®) diphenhydramine (Benadry®) clemastine (Tavist®) promethazine (Phergan®) Second generation No sedation blood-brain barrier Sniff, sniff: terfenadine (Seldane®) fexofenadine (Allegra®) cetirizine (Zyrtec®) loratadine (Claritin®) Cough Suppressants : Cough Suppressants Antitussives Decrease cough reflex Opioids codeine & hydrocodone Non-opioids dextromethorphan benzonatate (Tessalon®) Expectorants guaifenesin may work others are doubtful Mucolytics Decreases viscocity acetlycysteine (Mucomyst®) hypertonic saline