Breakthrough Treatment Solutions for Specific Skin Conditions :Breakthrough Treatment Solutions for Specific Skin Conditions The Next Level in Advanced Aesthetic Education


Slide 2:For the past 18 years, mesoestetic® pharmaceutical laboratories has specialized in the research, development and manufacturing of high quality professional cosmetic treatments.


Slide 3:MEDICAL EXPERIENCE RESEARCH TECHNOLOGY


Slide 4:As a world leader and pioneer in the cosmetic industry, mesoestetic® offers quick and efficient results for the patient, as well as, the medical professional.


Anatomy of the Skin :Anatomy of the Skin Epidermis is thinnest on the eyelids at .05 mm and the thickest on the palms and soles at 1.5 mm First 10 pages if skin were a 500 page book Dead or dying protective layer of skin cells Melanin “Stained” Dermis is 50x thicker than the Epidermis .3 mm on the eyelid and 3.0 mm on the back Source of Sweat, Oil and Hair Sensory Layers Blood Barrier 2000 oil glands per inch and most are on the face Network of Type 1 collagen and elastin Hypodermis subcutaneous tissue Deepest layer of the skin Blood vessels, nerves, lymph vessels, and hair follicles cross through this layer Acts both as an insulator, conserving body heat and as a shock absorber, protecting internal organs from injury


Depth of Aesthetic Treatment :Depth of Aesthetic Treatment Epidermis Chemical Peels Microdermabrasion Facials Waxing IPL/Laser Laser Hair Removal Cosmelan® Cosmelan Active Mesoéclat mesoestetic® Peels Radiance® Bx Anti-Aging Dermis Chemical Peels IPL/Laser Laser Hair Removal Dermal Fillers Cosmelan Cosmelan Active Mesoéclat mesoestetic® Peels Radiance® Bx Anti-Aging Hypodermis IPL/Laser Laser Hair Removal Botox®


pHScale :pHScale 0 1 2 3 5 6 8 9 10 11 12 7 13 4 14 Alkaline Acid Skin Chemical Peels Glycerin Soap H2O - Neutral Lye


Fitzpatrick Scale :Fitzpatrick Scale


Glogau Scale :Glogau Scale


Aging Skin :Aging Skin Definition of Aging The change or deterioration of cells, body function and skin with time due to environmental conditions, or the chronological passing of time


Aging Skin :Aging Skin Intrinsic vs. Extrinsic Intrinsic (Chronological Aging) Skin thins Loss elasticity Normal expression lines deepen Cell turnover slows Boundary between epidermis and dermis flattens Dermis begins to wither Number of blood vessels in dermis is diminished


Aging Skin :Aging Skin Intrinsic vs. Extrinsic Extrinsic (Environmental Aging) Epidermis thickens Structure of proteins becomes disorganized Impaired synthesis of collagen, elastin and proteins Pre-mature signs of aging Outside contributions; smoking, UV (photo damage), pollution, gravity, repetitive muscle movements, sleeping position


Cellular Degradation :Cellular Degradation Intrinsic Natural cell apoptosis Cellular respiration Glycolysis Mitochondria Extrinsic Free radicals Cell mutation, possible malignancy Smoking, pollution, gravity, sleeping position


Cellular Degradation :Cellular Degradation Breakdown of extra-cellular matrix Connective tissue destruction Proteoglycans, Collagen, Elastin, Proteins mesoestetic® pharmaceutical laboratories www.mesoesteticusa.com


Breakdown of Extra-Cellular Matrix :Breakdown of Extra-Cellular Matrix Normal extra cellular matrix Diabetic extra cellular matrix


Standard Treatment Options :Standard Treatment Options Topical Skin Care Products Microdermabrasion Peels Laser/IPL, Fraxel etc… Botox® Dermal Fillers


mesoestetic® Treatment Options for Aging Skin :mesoestetic® Treatment Options for Aging Skin Mesoéclat Radiance® Bx Anti-aging Treatment Lactic Peel Glycolic Peel Mandelic Peel Radiance® Skin Care Line


Acne :Acne Definition of Acne A skin condition characterized by inflammation and the excess production of oil from sebaceous glands in which the hair follicles become plugged


Acne :Acne


Types of Acne :Types of Acne Common Types of Acne Acne Cosmetica Hormonal Puberty Menstrual Menopausal Asphyxiated Genetics Systemic


Is it Acne? :Is it Acne? Not all breakouts are Acne Rosacea Eczema Folliculitis Keratosis Pilaris Perioral Dermatitis


Causes of Acne :Causes of Acne Follicular Keratinization Excessive cell build up on surface of the skin, clogging of the pore Sebaceous Activity Increase of androgen hormone (male) increases oil production. Excessive oil mixes with dead cells and causes blackheads Inflammation Inflammatory response causes redness & swelling P. Acnes (propianibacterium acnes) Active bacteria deep within the pore, breaks down oil in sebaceous gland causing inflammation, resulting in breakout or blemishes


Standard Treatment Options :Standard Treatment Options Facials Peels PDT (Levulan) Laser/IPL Oral Antibiotics Isotretinoin Topical Retinoids


New Theories in Treatment :New Theories in Treatment Regulating Sebaceous Gland Activity Shutting down sebaceous gland Accutane Oral antibiotics Shrinking sebaceous gland Laser/IPL Regulating sebum production Topical & Oral therapies Diphenhydramine HCI


mesoestetic® Treatment Options for Acne :mesoestetic® Treatment Options for Acne Cosmelan Active Cosmelan Active Skin Care System Professional Peels Salicylic Acid Mandelic Acid Glycolic Acid


Hyperpigmentation :Hyperpigmentation Definition of Hyperpigmentation The immune system triggers an inflammatory response, which then triggers melanocyte activity to protect the skin from heat, trauma and sun Normal Skin Melanotic hyperpigmentation (increased melanocyte number). Melanocytotic hyperpigmentation (normal melanocyte number but increased melanin production). Dermal hyperpigmentation with increased melanin within the dermis.


Hyperpigmentation :Hyperpigmentation Causes of Hyperpigmentation UV (Photo Damage) Excessive sun exposure Tanning beds Hormonal Melasma Menopausal Post Inflammatory Hyperpigmentation (PIH) Trauma Invasive skin treatments Burn


Slide 28:Metabolism of the Melanocyte THE PRODUCTION OF MELANIN Melanocytes Melanocytes – Form melanin in sub-cellular organelles Melanosomes - Act as specialized “carriers” for melanin production in the skin. Keratinocytes - Cells located in the basal layer of the epidermis Langerhans - Cells responsible for immune response. - Keratinocytes and Langerhans co-exist together


Metabolism of the MelanocyteTHE PRODUCTION OF MELANIN :Metabolism of the MelanocyteTHE PRODUCTION OF MELANIN Kinetics of the Cell: The Keratinocytes - exhibit an active process of keratinization, melanosomes deposit melanin in the keratinocytes transfering them upward to the corneocytes of the stratum corneum. The Corneocytes - along with ceramides and other lipids form the horny layer or stratum corneum and act as a protective mechanism of the skin.


Melanogenesis :Melanogenesis TYROSINASE (enzyme) TYROSINE (amino acid) TYROSINASE (enzyme) OXIDATION DOPA (amino acid) OXIDATION DOPAQUINONE (enzyme) PHEOMELANIN (red or yellow) EUMELANIN (brown or black)


Fitzpatrick Scale :Fitzpatrick Scale


Hereditary Influence :Hereditary Influence Arctic Region Low Sun Exposure Cold, Dry Melanocytes less reactive Scandinavia Russia Iceland Canada Equator Region High Sun Exposure Hot, Humid Melanocytes more reactive South America Africa Mediterranean Mexico Middle East Asia


Evaluating Hyperpigmentation :Evaluating Hyperpigmentation Epidermal Pigment - Hyperpigmentation is easily visible by Wood’s light


Evaluating Hyperpigmentation :Evaluating Hyperpigmentation Dermal/Epidermal Pigment or Mixed Pigment Some pigmentation is more noticeable than others under Wood’s light


Standard Treatment Options :Standard Treatment Options Microdermabrasion Peels Laser/IPL Tyrosinase Inhibitors & Lightening Agents Hydroquinone Kojic Acid Azelaic Acid Arbutin Retin A AHA’s Ascorbic Acid


mesoestetic® Treatment Options for Hyperpigmentation :mesoestetic® Treatment Options for Hyperpigmentation Cosmelan Depigmentation Treatment Professional Peels Mesoestetic Facial Line Radiance Skin Care Line


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments Mesoéclat Skin Rejuvenation Treatment Specifically developed to provide the greatest possible stimulation to cellular defense mechanisms and effectively fight against aging. The results are a “Re-awakening” of the skin, which brightens and revitalizes, improving firmness and elasticity


The Mesoéclat Method :The Mesoéclat Method Pre-exfoliating Solution Acts as a keratolytic, lowers the pH, allows for deeper penetration of active ingredient in ampoule Mesoéclat Ampoule Strengthens the connective tissue, firms and rejuvenates Mesoéclat Firming Cream Daily hydration, protects from free radicals, evens skin tone, firms and tightens skin


Mesoéclat Pre-exfoliating Solution :Mesoéclat Pre-exfoliating Solution Salicylic Acid BHA, encourages cell turnover and softening of pore congestion, anti-inflammatory Azelaic Acid Tyrosinase inhibitor, anti-bacterial, anti-fungal Allantoin Anti-inflammatory, antioxidant


Slide 41:Mesoéclat Pre-exfoliating Solution


Mesoéclat Pre-exfoliating Solution :Mesoéclat Pre-exfoliating Solution Pre-Exfoliating Solution Application Cleanse skin with mesoestetic® Milk or Gel Cleanser and follow with mesoestetic® Facial Tonic Dispense 1/5 of the Mesoéclat Pre-Exfoliating Solution and apply with a cotton or gauze pad Do not remove or neutralize and allow to dry


Mesoéclat Ampoule :Mesoéclat Ampoule Organic Silica Proteochondroitin sulphate L-Carnitine Alfa Lipoic Acid


Mesoéclat Ampoule :Mesoéclat Ampoule Organic Silica Naturally occurs in mineral or organic compounds Strengthens the connective tissue Essential component in healthy skin Regulates cellular metabolism Metabolic protector Proteochondroitin Sulfate Provides cohesion to the connective tissue Balances water & lipids in the connective tissue Binds with proteins strengthening elastin and improving firmness


Mesoéclat Ampoule :Mesoéclat Ampoule L-Carnitine Carrier of fatty acids to the inside of the mitochondria Antioxidant and cell energizer Stimulates cellular respiration Alpha Lipoic Acid Powerful antioxidant Natural photo protector Epidermal and dermal penetration capability


Mesoéclat Ampoule :Mesoéclat Ampoule Mesoéclat Ampoule Application Apply entire ampoule a small amount at a time with fan brush, fingertips or by injection (for trained professionals only) Massage skin allowing to penetrate completely, giving extra attention to expression lines, jaw line and neck Do not remove or neutralize


Mesoéclat Pre-exfoliating Solution :Mesoéclat Pre-exfoliating Solution


Mesoéclat Pre-exfoliating Solution :Mesoéclat Pre-exfoliating Solution


Mesoéclat Firming Cream :Mesoéclat Firming Cream Mesoéclat Firming Cream Vitamin E Kojic Acid Phytic Acid Sodium Pyruvate Phytotensors


The Mesoéclat Method :The Mesoéclat Method Mesoéclat Treatment Pack 1 pack per patient 5 sessions in treatment series One treatment every 7 to 14 days Maintenance – 1 treatment per month


Suggested Home Care Regimen :Suggested Home Care Regimen Mesoéclat Home Care Recommendation mesoestetic® Milk or Gel Cleanser mesoestetic® Facial Tonic mesoestetic® Antiaging Control Radiance® Bx Finishing Lines Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen


Mesoéclat Results :Mesoéclat Results Results Skin Re-Awakening Improvement of skin’s overall appearance Increased tissue respiration Better nourished skin Clearer complexion, less redness, improves actinic damage Not classified as an “anti-wrinkle” treatment however it will soften fine lines and prevents the formation of new wrinkles Excellent pre medical or surgical procedure treatment


Contraindications :Contraindications Do not use Mesoéclat during pregnancy or nursing Do not use Mesoéclat on irritated or inflamed skin Aspirin allergy


Slide 54:COMPLETE OPTION Mesoéclat Pack………………………………. $ 225.00 Prep Solution 5 Ampoules Mesoéclat maintenance cream Moisturizing Sun Screen 40+………………. $ 26.00 Anti-aging Control …………………………... $ 50.00 Radiance Bx Finishing Lines ……………… $ 75.00 Gel Cleanser or Milk Cleanser……………... $ 14.00 Facial Toner…………………………………… $ 16.00 Cost of Goods $ 406.00 Suggested Retail Price $ 875.00 5 SESSIONS x $ 175.00 Gross Profit $ 469.00 Patients Profit 1 2 3 4 5 10 15 $ 469.00 $ 938.00 $ 1,407.00 $ 1,876.00 $ 2,345.00 $ 4,690.00 $ 7,035.00 Mesoéclat Skin Rejuvenation Treatment REVENUE & PROFITS!


Before & After Photos :Before & After Photos


Before & After Photos :Before & After Photos


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments Radiance Bx Anti-Aging Treatment Designed to prevent and correct the signs of facial aging. This versatile cosmetic procedure fights both chronological and extrinsic damage. Scientifically advanced ingredients, clinically proven to reduce visible lines and wrinkles by inhibiting repetitive muscle motion, giving lifeless skin a renewed appearance.


Radiance Bx Anti-aging Treatment :Radiance Bx Anti-aging Treatment 4 Ampoules of Glycolic Acid + Vitamin E & F Glycolic Acid enhanced with antioxidants vitamins E & F, allows for cellular turnover and deep penetration of Perliotox solution 1 Vial of Perliotox Activator Offers a similar effect as Botox® inhibiting the neuromuscular receptors, suppressing the repetitive muscle motion. Softening fine lines and wrinkles 1 Vial of Perliotiox Solution Fortifies and protects cellular matrix while increasing active lipid function. Powerful humectant, anti-inflammatory and firming action 4 Single Dose Sachets of Radiance Bx Anti-aging Mask Antioxidants protect and revitalize dull, tired, aging skin. Rich emollients hydrate and improve skin texture. 1 Dosing Syringe


Glycolic Ampoule + Vitamin E & F :Glycolic Ampoule + Vitamin E & F Glycolic Acid 10% Naturally derived from sugar cane or rhubarb. Glycolic acid offers alpha hydroxy benefits, increasing cell turnover, clearing of pores and smoothing of skin texture. Vitamin E A powerful biological antioxidant that protects the cell membranes and prevents oxidation. It has lipophilic properties that help to maintain the moisture of the epidermis and protect it against environmental aggressions. Vitamin F An effective antioxidant that rejuvenates and speeds healing in the skin. A natural fatty acid, Vitamin F softens fine lines and smoothes skins texture and tone.


Glycolic Ampoule + Vitamin E & F :Glycolic Ampoule + Vitamin E & F Glycolic Ampoule Application Cleanse skin with mesoestetic® Milk or Gel Cleanser and follow with mesoestetic® Facial Tonic Gently massage contents of ampoule onto the skin. Pay extra attention to the areas of expression lines, jaw line and neck. Work into the skin for 3 minutes or until completely absorbed. Do not remove or neutralize


Perliotox :Perliotox Perliotox Active Peptide Solution A non-invasive topical cosmetic solution, used as an alternative to Botox®. It is used to reduce and/or eliminate the appearance of facial wrinkles and expression lines; such as crow’s feet, forehead lines and perioral areas.


Perliotox :Perliotox Perliotox Activator Pentapeptide-amide – 4 Offers a similar effect as Botox® inhibiting the neuromuscular receptors, suppressing the repetitive muscle motion. Softening fine lines and wrinkles Perliotox Solution Chondrus Crispus Rich in trace elements, this natural ingredient found in moss or Red Sea algae, offers both anti-inflammatory and anti-aging benefits. Glycerin A natural protector of the intercellular matrix, increases active lipids function in the skin and attracts water to the skin balancing hydration.


Perliotox :Perliotox Perliotox Application The Perliotox comes in two flasks; the Perliotox activator flask, contains the “freeze dried” peptide and the Perliotox solution flask, contains the active liquid which activates the peptide (see lid of Radiance Bx Treatment Pack for mixing instructions) With the plastic dosing syringe, take 1.5ml of the mixed solution, spread this solution over the surface of the face and neck, particularly over the areas with wrinkles and expression lines (contours of the eyes, forehead, nasal-labial area etc.) Allow solution to penetrate for 15 minutes or until completely absorbed. Do not remove. Storage and preservation of Perliotox Solution: The non-constituted product is stable for a period of three years, preferably at a temperature below 25ºC. The mixed product is stable for at least 1 month, recommended storage in a refrigerator or cool place.


Radiance Bx Mask :Radiance Bx Mask Coenzyme Q10 A very effective antioxidant, Coenzyme Q10 produces healthy respiration in the mitochondria, maintaining the integrity of the organelle while ensuring the strength of the extra-cellular matrix. Retinol Increases cellular turnover, regulating comedone activity and smoothing skin texture. Vitamin C Stimulates collagen synthesis, strengthening the skins structure and fights free radical damage caused by environmental and UV exposure. Vitamin E A powerful biological antioxidant that protects the cell membranes and prevents oxidation. It has lipophilic properties that help to maintain the moisture of the epidermis and protect it against environmental aggressions.


Radiance Bx Mask :Radiance Bx Mask Mask Application With a fan brush, apply a uniform layer of the Radiance Bx Mask over the face and neck, avoiding the contours of the eyes. Allow it to remain on the skin 10 minutes and remove with a tissue. Do not remove with water.


Radiance Bx Anti-aging Treatment :Radiance Bx Anti-aging Treatment Radiance Bx Treatment Pack 1 pack per patient 4 sessions in treatment series One treatment every 7 days Maintenance – 1 treatment per month


Home Care Maintenance :Home Care Maintenance Radiance Bx Finishing Lines Daily application first 4 weeks Apply twice a day, morning and evening, 2 or 3 pumps of Radiance Bx Finishing Lines over the face, neck and contours of the eyes, give extra attention to areas of expression lines. Allow the product to completely absorb. Month 2 – 4 Apply once a day, in the morning Continued use Apply once a day 3 times per week.


Radiance Bx Finishing Lines :Radiance Bx Finishing Lines Acetyl Hexapeptide – 3 This powerful peptide imitates the action of Botox® with 6 active amino acids. When applied topically Bx Finishing Lines penetrates the skins surface, suppressing the neurotransmitter which allows repetitive muscle motion


Suggested Home Care Regimen :Suggested Home Care Regimen Radiance Bx Home Care Regimen mesoestetic® Milk or Gel Cleanser mesoestetic® Facial Tonic mesoestetic Purifying Glycogel (oily skin) mesoestetic® Antiaging Control (dry skin) Radiance® Bx Finishing Lines Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen


Radiance Bx Anti-aging Treatment Results :Radiance Bx Anti-aging Treatment Results Results Prevents and corrects signs of aging Muscle relaxant with effect similar to Botox Powerful antioxidants neutralize free radicals Brightens complexion Topical firming Renewed hydration


Slide 71:COMPLETE OPTION Radiance Pack………………………………. $ 198.00 4 Glycolic Ampoules Perliotox Solution and Activator 4 Radiance Mask Sachets Bx Finishing Lines …………………………… $ 75.00 Moisturizing Sun Screen 40+………………. $ 26.00 Gel Cleanser or Milk Cleanser……………... $ 14.00 Facial Toner…………………………………… $ 16.00 Cost of Goods $ 329.00 Suggested Retail Price $ 700.00 4 SESSIONS x $ 175.00 Gross Profit $ 371.00 Patients Profit 1 2 3 4 5 10 15 $ 371.00 $ 742.00 $ 1,113.00 $ 1,484.00 $ 1,855.00 $ 3,710.00 $ 5,565.00 Radiance Bx Anti-aging Treatment REVENUE & PROFITS!


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments mesoestetic® Professional Peels State-of-the-art formulations which infuse the skin with beneficial antioxidants and cellular regenerating agents. This advanced technology produces a less invasive solution and minimal downtime. Four unique formulas include; Lactic, Mandelic, Salicylic and Glycolic with a range of active graduations tailored to the nature and intensity of the skin condition


Professional Peels :Professional Peels Professional Peel Pack Peel Solution Post Peel Neutralizing Spray Complimentary Treatment Products Professional Degreasing Solution Fast Skin Repair


Professional Peels :Professional Peels Professional Peel Solutions Active Ingredients: Arginine - Amino acid that has antioxidant properties and can be helpful for wound healing Glycine – Antioxidant and wound-healing properties pH: 1.8 Cosmetic Form: Transparent Gel containing no preservatives Attainable results Very Superficial Superficial Medium


Peel Formulations :Peel Formulations Glycolic Acid – 99% pure acid AHA naturally derived from sugar cane or rhubarb. Small molecular structure allows for deep penetration Concentrations: 20%, 35%, 50% and 70% Recommendations & Benefits: Softens fine lines and wrinkles Photo-aging Improves skin pigmentation Stimulates formation of collagen and elastin Treats comedonel type congestion


Peel Formulations :Peel Formulations Mandelic Acid – 98% pure acid AHA naturally derived from bitter almonds. Small molecular structure, not as acidic as Glycolic Concentrations: 30%, 40% and 50% Recommendations & Benefits: Combination skin types Acne mixed with photo-aging and/or hyperpigmentation Very gentle, no visible alterations to skin, no downtime Antiseptic properties


Peel Formulations :Peel Formulations Salicylic Acid – 99% pure BHA naturally derived from wintergreen or willow bark Concentrations: 10%, 20% and 30% Recommendations & Benefits: Ideal for treating congested skin conditions Softens acne scars at low percentages, eliminates scars at higher percentages Effectively treats hyperkeratosis Fades dyschromia due to photo damage Softens fine lines and wrinkles Excellent choice for oily, acne prone complexions Some cases of Rosacea


Peel Formulations :Peel Formulations Lactic Acid – 95% pure AHA naturally derived from fermented milk Concentrations: 30%, 40% and 50% Recommendations & Benefits: Photo-aging Softens fine lines and wrinkles Hydrating Stimulates collagen and elastin Excellent choice for dryer skin types


Indications of Peels :Indications of Peels Peel intensity is dependent on the following Concentration of the peel solution (%) Time on tissue Anatomical areas of treatment, face, hands, back, neck, décolleté, due to thickness of skin Formulation of solution pH of solution Skin Type Consideration A patch test should be done on skin types IV – VI when using solutions of 30% or higher


Indications of Peels :Indications of Peels Occasional Symptoms Excess penetration of acids can cause a frost or blanch Frost – Salt residue, visible when using Salicylic Acid Wipes away easily No long term effects on skin Blanch – Protein coagulation Scab will form & peel off in a few days Do not pull at peeling skin Skin will re-epithelialize


Professional Peels :Professional Peels Peel Application Cleanse skin with mesoestetic® Cleansing Milk or Gel, rinse with warm water and follow with mesoestetic® Facial Toner. Apply the mesoestetic® Professional Degreasing Solution with a cotton pad. If patient has particular areas of sensitivity from degreasing solution, be cautious with peel application in those areas as deeper penetration may occur and cause blanching. Apply an even application of peel solution with a facial fan brush. Peel solution is active, patient may experience a mild to moderate warmth and/or tingling sensation. Fanning the skin will make the patient more comfortable. Allow peel solution to remain on the skin between 3 and 15 minutes depending on the type and percentage of solution. If the patient begins to feel a constant sensation of heat or is uncomfortable it is time to neutralize. Be observant of the skin, if there are areas of severe erythema or irritation lessen the time on tissue. (see suggested times below)


Professional Peels :Professional Peels After time has elapsed remove peel solution with an abundant amount of water. Patient may experience some “heat” at this time, work quickly removing the solution followed by the Post Peel Neutralizing Spray. Apply Post Peel Neutralizing Spray and spread evenly over treated area with cotton pad. Neutralizing spray is best applied cold, to soothe skin and assist in reducing heat sensation and itching. Once the skin has calmed, rinse the skin a final time with warm water. Apply mesoestetic® Fast Skin Repair to the area of treatment. Lightly massage into skin paying special attention to sensitive areas. Complete with an application of mesoestetic® Complete Moisturizing Sunscreen (for normal to dry skin) or mesoestetic® Dermatological Complete Sunscreen (for combination to oily skin).


Professional Peels :Professional Peels


mesoestetic® Professional Peels :mesoestetic® Professional Peels Professional Peel Pack Up to 10 treatment per 50ml. bottle of solution Average recommended treatments per series 3 to 6 Peels may be given 2 to 3 weeks apart Maintenance 1 treatment per month


Complimentary Professional Treatment Products :Complimentary Professional Treatment Products Professional Degreasing Solution Promotes superficial exfoliation. Use as a pre-treatment solution prior to cosmetic treatments. Glycolic and Salicylic acids enhance this unique formulation. Additional benefits: antiseptic, decongestive and evening of skin tone Fast Skin Repair An intensive repair cream which restores, revitalizes and calms the skin. Active ingredient B-Glucan offers skin regenerating properties and DMAE improves skin elasticity, both are powerful anti-aging ingredients.


Suggested Home Care Regimen :Suggested Home Care Regimen Professional Peel Home Care Regimen mesoestetic® Milk or Gel Cleanser mesoestetic® Facial Tonic Fast Skin Repair (twice a day for 5 days post peel) Facial Mask 2 Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen Radiance Eye Lift, Serum Intensive, Bx Finishing Lines, Day or Night Pearls (depending on skin type and condition)


Professional Peel Results :Professional Peel Results Results Improved texture Stimulates collagen and elastin production Brightens complexion Reduces oil and acneic activity Treats photo damage Lightens pigmentations Softens fine lines and wrinkles


Contraindications :Contraindications Pregnancy or nursing Use of retinoids or depigmentation treatments Cold sores Flat warts Keloid scars Aspirin allergy Recent facial surgery Waxing


Slide 89:COMPLETE OPTION Professional Peel Pack……………………… $ 75.00 1 bottle peel solution (50ml.) 1 bottle neutralizing solution (50ml.) Moisturizing Sun Screen 40+………………. $ 26.00 Fast Skin Repair …………………………... $ 45.00 Professional Degreasing Solution…...…… $ 32.00 Gel Cleanser or Milk Cleanser……………... $ 14.00 Facial Toner…………………………………… $ 16.00 Cost of Goods $ 208.00 Suggested Retail Price $ 750.00 6 SESSIONS x $ 125.00 Gross Profit $ 542.00 Patients Profit 1 2 3 4 5 10 15 $ 542.00 $ 1,084.00 $ 1,626.00 $ 2,168.00 $ 2,710.00 $ 5,420.00 $ 8,130.00 mesoestetic® Professional Peels REVENUE & PROFITS!


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments Cosmelan Active Anti-Acne System Cleanses and regulates oily skin conditions and those with a tendency toward acne. This active treatment offers astringent, exfoliating and keratolitic properties and helps to absorb cutaneous sebum build up. It decongests the pores and eliminates dead cells, facilitating the normal functioning of the sebaceous glands. It eliminates post inflammatory pigment and heals breakout without causing excessive dryness giving a moisturizing and calming action.


Cosmelan Active Anti-Acne System :Cosmelan Active Anti-Acne System Degreasing Solution Pre-treatment solution, purifies, degreases and lower pH Cosmelan Active Mask Promotes healing with an astringent effect. Exfoliating and keratolytic properties, reduces sebum and controls breakout Cosmelan Active Cleanser Gentle gel cleanser, compliments treatment results Cosmelan Active Spot Treatment Occasional spot treatment to speed healing of blemishes Cosmelan Active Maintenance Cream Increases superficial cellular turnover and prevents congestion in pores. Regulates sebum production and softens inflammatory pigment


Cosmelan Active Mask :Cosmelan Active Mask Azelaic Acid Derived from oxygenating oleic acid, found in milk or naturally in many grains. Tyrosinase inhibitor, fights oxidation of pigmentation from UVA rays, lightens hyperpigmentation, anti-fungal and anti-bacterial Kojic Acid Derived from mushrooms acts as a tyrosinase inhibitor, fights oxidation, lightens hyperpigmentation, anti-fungal and anti-bacterial Resorcinol Derived from wood bark, offers keratolytic properties and acts as a flaking agent. In low concentrations Resorcinol offers antiseptic benefits Salicylic Acid Naturally derived from wintergreen leaves, a beta hydroxy acid and a keratolytic. Very effective in treating acne by eliminating dead cell accumulation and reducing impacted debris in the pores Zinc Oxide A powerful anti-inflammatory and healing agent. Zinc is often used in UVA/UVB sunscreens and offers a physical block from solar radiation Bisabolol Derived from Chamomile, with powerful anti-inflammatory action


Cosmelan Active Anti-Acne System :Cosmelan Active Anti-Acne System In Office Treatment Application Cleanse skin with mesoestetic® Milk or Gel Cleanser and follow with mesoestetic® Facial Tonic Apply the degreasing Solution with a cotton pad. Do not remove Apply ½ of the Cosmelan Active Mask, using gloved fingertips and spreading evenly over the face. Save the remaining ½ of the mask for a second treatment The Cosmelan Active Mask is to remain on the skin for 3 to 4 hours and is then removed by the patient at home, with warm water and Cosmelan Active Cleanser


Cosmelan Active Anti-Acne System :Cosmelan Active Anti-Acne System Suggested Professional Protocol One week after the initial Cosmelan Active Mask application, treat the skin with a basic cleansing facial and extractions Two to four weeks after the initial mask treatment, repeat the mask application protocol once again in office. Repeat time of application and continue with home care regimen


Cosmelan Active Home Care Protocol :Cosmelan Active Home Care Protocol Cosmelan Active Cleanser Day of mask application After recommended time of application has elapsed, remove the Cosmelan Active Mask with Cosmelan Active Cleansing Gel and warm water. Immediately after removing mask, apply a small amount of the Cosmelan Active Maintenance Cream over the entire facial area. This cream will soothe and hydrate the skin, while contributing to the healing and clearing of the complexion.


Cosmelan Active Home Care Protocol :Cosmelan Active Home Care Protocol Continued Daily Maintenance Wash both morning and evening with Cosmelan Active Cleansing Gel and warm water Apply a small amount of the Cosmelan Active Maintenance Cream over the entire facial area. This cream will soothe and hydrate the skin, while contributing to the healing and clearing of the complexion Cosmelan Active Daily Spot Treatment may be used 3 – 6 times per day on targeted blemishes. Regular use reduces redness and inhibits the formation of blemishes. Complete with an application of mesoestetic® Complete Moisturizing Sunscreen (for normal to dry skin) or mesoestetic® Dermatological Complete Sunscreen (for combination to oily skin)


Cosmelan Active Anti-Acne System & Maintenance Pack :Cosmelan Active Anti-Acne System & Maintenance Pack Cosmelan Active Anti-Acne System 1 pack per patient 1 jar of Cosmelan Mask, divide into 2 applications One treatment every 2 to 4 weeks Maintenance: Salicylic Acid peel once a month Cosmelan Active Maintenance Pack 4 weeks of daily anti-acne home care products


Cosmelan Active Results :Cosmelan Active Results Results Controlled sebum production Healing of blemishes Fading of inflammatory pigmentations Clearing of pores Elimination of excessive cell buildup Prevents future breakouts Safe for all grades of acne


Contraindications :Contraindications Pregnancy or nursing Rosacea Avoid contact with the eyes and mucous membranes. In the event of accidental contact; wash with abundant amount of water Discontinue the use of glycolic, benzoyl peroxide, retinols and other depigmentation treatments 7 to 10 days prior to giving treatment. The use of any glycolic, benzoyl peroxide, retinols other depigmentation products is not recommended during treatment in order to prevent any unpleasant or unexpected interactions.


Cosmelan Active :Cosmelan Active Cosmelan Active Pack………………………………. $ 245.00 Prep Solution Cosmelan Active Mask Cosmelan Active Cleanser Cosmelan Active Maintenance Cream Cosmelan Active Spot Treatment Moisturizing Sunscreen 40+………………. $ 26.00 Cost of Goods $ 271.00 Suggested Retail Price $ 600.00 Gross Profit $ 329.00 No. of Patients Profit Cosmelan Treatment 1 2 3 4 5 10 $ 329.00 $ 658.00 $ 987.00 $ 1,316.00 $ 1,645.00 $ 3,290.00 REVENUE & PROFITS!


Before & After Photos :Before & After Photos Before Mask Application 1st Mask Application


Before & After Photos :Before & After Photos Prior to 2nd Mask Application – Day 14 Day 21 – 7 days after 2nd Mask Application


mesoestetic® Professional Treatments :mesoestetic® Professional Treatments Cosmelan Depigmentation Treatment Based on the inhibition of tyrosinase, a basic enzyme in the production of melanin. The active ingredients in Cosmelan® block this enzyme, inhibiting the cycle of melanogenesis while eliminating epidermal pigment. This dynamic process offers many advantages over other depigmentation treatments found in the market today


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment Why Cosmelan VERY EFFICIENT IN ALL TYPES OF MELASMA, CHLOASMA, UV DAMAGE & PIH PREVENTION OF PIH POST PEELS AND LASER TREATMENTS NON-INVASIVE DEPIGMENTATION ACTION COMPATIBLE WITH ALL SKIN TYPES (I-VI) LIGHT PEELING EFFECT REJUVENATION AND LUMINOSITY OF THE SKIN TREATMENT CAN START AND BE USED ALL YEAR ROUND, NOT PHOTOSYNTESIZING DOES NOT CONTAIN TCA VERY SAFE


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment Degreasing Solution Pre-treatment solution, purifies, degreases and lower pH Cosmelan 1 Mask Active formulation reduces hyperpigmentation, increases hydration and promotes a brighter more luminous skin Cosmelan 2 Maintenance Cream Continues lightening process initiated by Cosmelan Mask. Active tyrosinase inhibitors suppress melanocyte activity HydraVital Factor K Hydrating moisturizer that infuses nutrients and antioxidants into the skin. Anti-inflammatory agents protect and soothe.


Cosmelan 1 & 2 :Cosmelan 1 & 2 Kojic Acid Azelaic Acid Arbutin Phytic Acid Licorice Extract Salicylic Acid Retinol Palmitate Ascorbic Acid Tocopherol Bisabolol Allantoin Nicotinamide Aloe Barbadensis Titanium Dioxide


Actions of Cosmelan Ingredients :Actions of Cosmelan Ingredients Reversible Tyrosinase Inhibitors: Elevates tyrosinase inhibition. Ingredients of both plant and chemical origin, formulated to achieve maximum inhibition strength and are well tolerated and safe. Dopaquinone and Eumelanin Inhibitors: Ingredients of chemical origin acting as enzymatic inhibitors in the more advanced phases of melanogenesis. Diverting dark pigment to light Complementary Melanogenesis Inhibitors: Inhibits the transfer of melanosomes to keratinocytes and cancels out any ultraviolet radiation stimulation. Vitamin Complex: Antioxidant properties, free radical neutralizers which stimulate fibroblast collagen-producing activities and cellular renovation and have a revitalizing effect on the skin. Plant Extract Complex: These are substances of plant origin exhibiting a brightening, hydrating and anti-inflammatory effect on the skin. Filtering Complex: This is a mixture of organic and inorganic filters producing no free radicals and absorbing UVA and UVB radiation. Exfoliating Agent: Exfoliating agents that accelerate the stratum corneum desquamation or shedding process and therefore assists in melanin elimination.


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment Cosmelan Mask Application Cleanse skin with mesoestetic® Milk or Gel Cleanser and follow with mesoestetic® Facial Tonic Apply the degreasing Solution with a cotton pad. Do not remove Apply ¾ of the Cosmelan Mask, using gloved fingertips. Apply thick layer over the areas with heaviest pigmentation, spreading evenly over the rest of the face. Save the remaining ¼ of the mask for a touch up treatment which will be given 3 weeks after initial mask application


Cosmelan Mask Application :Cosmelan Mask Application


Cosmelan Mask Application :Cosmelan Mask Application Initial Mask Application Touch Up Treatment


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment The Cosmelan Mask is to remain on the skin according to the recommended time of application chart below These are recommended application times only. Consideration should be taken in accordance to skin sensitivity, evolution of pigment, and professional experience with the product.


Cosmelan Home Care Protocol :Cosmelan Home Care Protocol 1st DAY – Mask Day After the action time indicated has elapsed, the patient must remove the mask with neutral cleanser and water Immediately following, the patient will apply mesoestetic® Hydravital Factor K cream over the entire treated area 2nd DAY – First 2 Weeks The patient will begin applying Cosmelan® 2 Maintenance Cream 3 x per day (for best results) minimum of 2 x per day 15 minutes after each application of Cosmelan® 2, the patient will apply mesoestetic® Hydravital Factor K cream on top of Cosmelan® 2. mesoestetic® Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen must be used every day.


Cosmelan Home Care Protocol :Cosmelan Home Care Protocol Week 3 – Week 10 Apply Cosmelan® 2 twice a day 15 minutes after each application of Cosmelan® 2, the patient will apply mesoestetic® Hydravital Factor K cream on top of Cosmelan® 2. mesoestetic® Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen must be used every day. Week 11 – 6 Months Apply Cosmelan® 2 once a day 15 minutes after each application of Cosmelan® 2, the patient will apply mesoestetic® Hydravital Factor K cream on top of Cosmelan® 2. mesoestetic® Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen must be used every day.


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment Cosmelan Treatment Pack 1 pack per patient 1 jar of Cosmelan Mask, 2 applications Touch up treatment 14 to 21 days after initial mask application Maintenance: Use Cosmelan 2 for a minimum of 6 months to 1 year. Full treatment may repeated every 4 to 6 months


Suggested Home Care Regimen :Suggested Home Care Regimen Cosmelan Home Care Regimen mesoestetic® Milk or Gel Cleanser mesoestetic® Facial Tonic Radiance Eyelift Facial Mask 2 Complete Moisturizing Sunscreen or Dermatological Complete Sunscreen


Cosmelan Depigmentation Treatment :Cosmelan Depigmentation Treatment Results & Benefits Effective in treating; Melasma, Chloasma, Photo Damage and PIH Prevention of PIH post laser/IPL or peels Non-invasive depigmentation action Rejuvenation and luminosity Safe for all skin types No downtime


Contraindications :Contraindications Do not use the Cosmelan Method during pregnancy or nursing Do not use on Rosacea Avoid contact with the eyes and mucous membranes. In the event of accidental contact; wash with abundant amount of water Discontinue the use of glycolic, retinols and other depigmentation treatments 7 to 10 days prior to giving treatment. The use of any other depigmentation products is not recommended during treatment in order to prevent any unpleasant or unexpected interactions.


Cosmelan Depigmentation Treatment :OPTION 2 – COMPLETE Cosmelan Pack………………………………. $ 265.00 Prep Solution Cosmelan 1 Mask Cosmelan 2 Home Maintenance Hydra Vital Factor K Cream Moisturizing Sun Screen 40+………………... $ 26.00 Gel Cleanser or Milk Cleanser……………… $ 14.00 Facial Toner…………………………………… $ 16.00 Eye Lift…………………………………………. $ 53.00 Cost of Goods $ 374.00 Suggested Retail Price $ 850.00 Gross Profit $ 476.00 No. of Patients Profit Cosmelan Treatment 1 2 3 4 5 10 15 $ 476.00 $ 952.00 $ 1,428.00 $ 1,904.00 $ 2,380.00 $ 4,760.00 $ 7,140.00 REVENUE & PROFITS! Cosmelan Depigmentation Treatment


Before & After Photos :Before & After Photos Before Mask Application Day 28 – 1 Month after initial mask – 1 Week after touch up


Before & After Photos :Before & After Photos


Before & After Photos :Before & After Photos


Before & After Photos :Before & After Photos