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By: akki1347 (39 month(s) ago)

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Smoking and Type-2 Diabetes Mellitus: 

Smoking and Type-2 Diabetes Mellitus Toshimi Sairenchi, M.Sc. Ibaraki Health Plaza, Ibaraki Health Service Association, Ibaraki-ken, JAPAN

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

Prevalence of diabetes among Japanese men: 

Prevalence of diabetes among Japanese men (Ministry of Health, Labour and Welfare Japan, 2004) All age 20-29 30-39 40-49 50-59 60-69 70- Age (years) HbA1c(%)>6.1 or medication 5.6<HbA1c(%)<6.1 without medication Left bar: in 1997 Right bar : in 2002

Prevalence of diabetes among Japanese women: 

(Ministry of Health, Labour and Welfare Japan, 2004) Prevalence of diabetes among Japanese women 40-49 50-59 60-69 70- Age (years) HbA1c(%) > 6.1 or medication 5.6 < HbA1c(%)<6.1 without medication Left bar: in 1997 Right bar: in 2002

Notice: 

Notice The proportion of diabetes of borderline type increased in the elderly for both sexes. Type-2 diabetes mellitus among elderly is an increasing public health problem.

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

Follow-up studies for smoking and type-2 diabetes mellitus among middle-aged persons: 

Follow-up studies for smoking and type-2 diabetes mellitus among middle-aged persons

Sex-specific risk ratios for type-2 diabetes mellitus according smoking habits among 275,190 men and 434,637 women: 

Sex-specific risk ratios for type-2 diabetes mellitus according smoking habits among 275,190 men and 434,637 women (Will JC. et al., 2001)

Next Question: 

Next Question Smoking is a risk of diabetes mellitus among middle-aged men and women. Is there a relationship between smoking and risk of diabetes mellitus among elderly?

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

Age-specific risk ratios for type-2 diabetes mellitus according to smoking habits among 39,528 men, Japan, 1993-2002: 

Age-specific risk ratios for type-2 diabetes mellitus according to smoking habits among 39,528 men, Japan, 1993-2002 (Sairenchi T. et al., 2004)

Age-specific risk ratios for type-2 diabetes mellitus according to smoking habits among 88,613 women, Japan, 1993-2002: 

Age-specific risk ratios for type-2 diabetes mellitus according to smoking habits among 88,613 women, Japan, 1993-2002 (Sairenchi T. et al., 2004)

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

One of the possible mechanisms: 

One of the possible mechanisms Insulin action Smoking Oxdative stress Diabetes mellitus Bridges AB. et al., 1993 Paolisso G, et el., 1993

Contents: 

Contents Epidemiology of type-2 diabetes mellitus in Japan Smoking and type-2 diabetes mellitus in middle-aged population Smoking and type-2 diabetes mellitus in elderly population Possible mechanism Conclusion

Smoking and type-2 diabetes: 

Smoking and type-2 diabetes Smoking is a risk factor of type-2 diabetes mellitus not only among middle-aged but also among elderly men and women.