Hepatitis D (Delta) Virus:
Hepatitis D (Delta) Virus
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Geographic Distribution of HDV Infection
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Coinfection with HBV
severe acute disease
low risk of chronic infection
Superinfection on top of chronic HBV
usually develop chronic HDV infection
high risk of severe chronic liver disease Hepatitis D - Clinical Features
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HBV – HDV Coinfection
Typical Serological Course
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HBV – HDV Super-infection
Typical Serological Course
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Percutanous exposures
injecting drug use
Permucosal exposures
sex contact Hepatitis D Virus
Modes of Transmission
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HBV-HDV Coinfection
Pre or postexposure prophylaxis to prevent HBV infection (HBIG and/or Hepatitis B vaccine)
HBV-HDV Superinfection
Education to reduce risk behaviors among persons with chronic HBV infection Hepatitis D - Prevention