AdvManufacturing SwedishLifeScience

Sweden for Advanced Manufacturing in Life Sciences: 

Sweden for Advanced Manufacturing in Life Sciences Ylva Williams, Invest in Sweden Agency

Agenda 1) A world-class manufacturing location2) Source of great life science3) Advanced manufacturing in life sciences: 

Agenda 1) A world-class manufacturing location 2) Source of great life science 3) Advanced manufacturing in life sciences

Sweden A world-class manufacturing location: 

Sweden A world-class manufacturing location

Introduction to Sweden: 

Introduction to Sweden Largest country in northern Europe Winner men’s Ice Hockey 2006 Olympics A country with great manufacturing expertise Home to world-leading manufacturers

Slide5: 

Manufacturing know-how behind success Labor productivity, average annual increase 1994-2003, percent Source: US Department of Labor, 2004

Profitable production in Sweden: 

Profitable production in Sweden Scania Volvo Cars Sandvik SKF Getinge

Swedish manufacturing strengths : 

Swedish manufacturing strengths Holistic approach and system thinking Complex products and production systems Integration of R&D, design and production Advanced materials flows Competence Communication and accord Working methods Corporate culture Delegation of responsibility Constructive employer/union relations Internationally competitive education/research Clusters of internationally strong companies Transports/logistics Management Business acumen Manufacturing systems

Efficient logistics and distribution networks: 

Efficient logistics and distribution networks ”Centralizing logistics activities to Sweden has shortened delivery lead times, reduced warehousing costs and increased total delivery quality.” Hideo Masuda Managing Director Honda Nordic

Recent manufacturing expansions: 

Recent manufacturing expansions ABB From Switzerland to Västerås AstraZeneca Expansion in Södertälje Atlas Copco From the US to Örebro Ericsson From Hungary to Vaggeryd GE Healthcare From the US to Umeå Getinge From France, Netherlands, Italy and the US Sandvik From Mexico to Sandviken Scania From the Netherlands to Oskarshamn Toyota Industries Expansion in Mjölby Source: Invest in Sweden Agency et al., "Cost or competence? Case studies of companies that have moved production to Sweden", 2005§

Source of great life science: 

Source of great life science

Rich history: 

Rich history The Nobel Prize award ceremony is held annually in Stockholm Astra Astra founded 1913, today part of AstraZeneca Global R&D headquarters in Södertälje Research HQ for gastrointestinal and cardiovascular research in Göteborg Research HQ for neuroscience in Södertälje Pharmacia Founded in 1911, today part of Pfizer Spin-offs: Pharmacia Diagnostics, Pharmacia Biotech (now GE Healthcare) Home of Karolinska Institutet and the Nobel Prize Today: 40,000-strong life science sector

Industry with focus on Drug development, Medical Device and Biotech Tools: 

Industry with focus on Drug development, Medical Device and Biotech Tools Source: "Swedish Biotechnology", Vinnova 2005 Distribution 2004 by number of employees AstraZeneca, Pfizer, Biovitrum, KaroBio, Active Biotech, Medivir Quintiles, TFS Trial Form Support Gambro, Elekta, Siemens-Elema, St. Jude Medical, Nobel Biocare, Astra Tech GE Healthcare, Getinge, Biacore, Biotage, Vitrolife, Fresenius Kabi, Q-Med Pharmacia Diagnostics, Biodisk, CanAg Diagnostics DSM Anti-Infectives Sweden, Ferring, Novozymes Biopharma * Bioproduction at Pfizer and Biovitrum included in ”Drug Development & Manuf.” *

Home to some of Europe’s finest clusters: 

Home to some of Europe’s finest clusters Stockholm/Uppsala Göteborg Region Malmö/Lund/Copenhagen=Medicon Valley

Swedish research breakthroughsDrug development and biotechnology: 

Swedish research breakthroughs Drug development and biotechnology XylocainTM, local anestethics (Astra) Dextran, MacrodexTM, and RheomacrodexTM, blood plasma substitutes (Pharmacia) SalazopyrinTM, anti-inflammatory (Pharmacia) L-dopa (Arvid Carlsson) AptinTM, non-selective betablocker (Astra) Amipaque, nonionic x-ray contrast medium (Nyegaard & Co) Bricanyl, selective beta 2 stimulator (Astra) HealonTM, ophthalmic device (Pharmacia) SelokenTM, selective beta 1 blocker (Astra) Thromboxanes, (Bengt Samuelsson, Hans Bergström) PulmicortTM, cortico-steroid (Astra) FragminTM, low-molecular-weight heparin (Pharmacia) GenotropinTM, human growth hormone (Kabi Vitrum and Genentech U.S.) LosecTM/PrilosecTM, ulcer medicine (Astra) PlendilTM, calcium antagonist (Astra)  NexiumTM, proton pump inhibitor (AstraZeneca) NexiumTM, AstraZeneca

Swedish research breakthroughsMedical devices, diagnostics & biotech supplies : 

Swedish research breakthroughs Medical devices, diagnostics & biotech supplies Sephadex, gel filtration chromatography Pharmacia Biotech Artificial kidney Gambro IgE allergy diagnosis Pharmacia Diagnostics Respirator Siemens-Elema Implantable pacemaker Siemens-Elema Brånemark implant systems Nobel Biocare Gamma knife Elekta DNA sequencing technology Biotage Biosensors Biacore Next successes? Aerocrine, Affibody, Global Genomics, Olink Elekta Gamma Knife

Europe’s fourth-largest biotech industryNumber of companies: 

Europe’s fourth-largest biotech industry Number of companies Source: Ernst & Young, "Global Biotechnology Report – The European Perspective", 2004

Sweden for advanced manufacturing in life sciences : 

Sweden for advanced manufacturing in life sciences

GE Healthcare: 

GE Healthcare $15 million of sales in medical equipment Major facilities in Uppsala and Umeå – global centres of manufacturing excellence Several manufacturing moves to Sweden since 2001, in drive for increased profitability $ 90 million investment in Uppsala facilities announced 2005 “vote of confidence for protein separation activities in Sweden.” ”Sweden offered better competence overall and our production infrastructure was superior.” Peter Ehrenheim President Protein Separations GE Healthcare

Pfizer: 

Pfizer One of the world’s largest pharmaceuticals companies Chose Sweden over ten other possible manufacturing sites for new biomanufacturing plant in Strängnäs $150 million to be invested Site in Helsingborg global center of excellence for consumer health care products ”Sweden has the know-how required to build ultra-modern plants for advanced biotechnological manufacturing.”

St Jude Medical: 

St Jude Medical Global cardiovascular device company. $2.3 billion in sales and nearly 8,000 employees. Sweden one of two global centers of excellence for pacemakers. 250 staff in production. Sweden important part of success Favors having R&D at same location – easier to effectively implement design for manufacturability into products ”The flexibility in aggressively ramping up production has allowed us to meet demand across the board for all of our products.” Michael Coyle President Cardiac Rhythm Management Division St Jude Medical

Advanced Medical Optics: 

Advanced Medical Optics US-based company focused on vision technologies Acquired Pfizer’s Healon® activities in 2004 Invests in Sweden: Has moved manufacturing from Ireland to Sweden Moves R&D from US to Sweden Why Sweden? Know-how, access to skilled staff and proximity to world-leading university

SPX Air Filtration: 

SPX Air Filtration Part of SPX Corporation with 25,000 employees, $ 5 billion in sales Supplies air filters for pharmaceutical applications Concentrates all manufacturing of synthetic bag filters to Sweden Production in Sweden to be doubled from summer 2006 - to supply globally CEO: “We showed that Sweden is a world-class manufacturing site.”

Good reasons to place manufacturing activities in Sweden: 

Good reasons to place manufacturing activities in Sweden

Good reasons to place manufacturing activities in Sweden: 

Good reasons to place manufacturing activities in Sweden A world-class manufacturing location; - productivity, production systems, logistics… Offers great expertise in design, development, quality control and manufacturing Leading pharma, medical device and biotech industries Competitive salary levels and operating costs Cutting-edge academia in both life science and manufacturing Great skill in integrating R&D and production Good access to skilled staff Sweden creates high value-add in production ”Sweden offers knowledgeable engineers in all areas that are relevant, including biochemistry, chemistry, electronics and machine design.” Peter Ehrenheim President Protein Separations GE Healthcare

Contacts & further information: 

Contacts & further information Ylva Williams Head of Life Science Tel: +46 8 402 78 80 ylva.williams@isa.se ISA website contains wealth of information for investors