MSU CSIDC

Weariness Diagnosis System: 

Weariness Diagnosis System Portable Medical System from Moscow State University

Moscow State University team: 

Moscow State University team Faculty mentor: prof. V. P. Ivannikov mentor’s assistant: A. Chernov Team members: P. Iakovenko A. Khokhlov A. Petrov D. Vassioura

Contents: 

Contents Purpose and use of the system Theoretical foundations Architecture overview Conclusions

Purpose of the system: 

Purpose of the system Provide a mean for real-time diagnostics based on heart rate Provide a facility for long-term data storage Allow a doctor reporting a new diagnosis to the patient Allow easy extension of the system with new diagnostics methods

Areas of application: 

Areas of application Human safety-related professions (pilots, drivers, etc) Risk groups (myocardial infarction, etc) General public as health self-monitoring appliance

Theoretical foundations: 

Theoretical foundations Mathematical analysis of cardiac rhythm - a way to examine functional condition of an organism Two-circuit model of cardiac rhythm control by Baevsky R.M. Characteristics of regulation systems Measurement of showings for the certain characteristics

Theoretical foundations (cont.): 

Theoretical foundations (cont.) The regulatory system activity showing (RSAS) - the integral value Medical interpretation of RSAS

Medical works used: 

Medical works used Parin V.V., Baevsky R.M., “Introduction to medical cybernetics”. Moscow: Praga, 1966 Baevsky R.M., Kirillov O.I., Kletskin S.M. “Mathematical analysis of cardiac rhythm variation at stress”. Moscow: Science, 1984 Baevsky R.M., Berseneva A.P., “Estimation of adaptable opportunities of an organism and risk of development of diseases”. Moscow: Medicine, 1997

Cardiac intervals (R-R intervals) : 

Cardiac intervals (R-R intervals)

Two-circuit model by Baevsky: 

Two-circuit model by Baevsky Sinus node Autonomous system Level A - organism reorganization due to environmental factors Level B - regulation of interaction between different systems Level C - parameter aligning inside certain systems Regulatory system Environment S V NC HC S, V, NC, HC - nervous control channels

Cardiac rhythm analysis methods: 

Cardiac rhythm analysis methods Analysis of average, transitional and instant values of heartbeat frequency Heart rate variability analysis Cardiac rhythm trend analysis Evaluation of Regulator Systems condition Statistical analysis Variation analysis Correlation analysis Spectral analysis

The characteristics of cardiac rhythm regulation systems: 

The characteristics of cardiac rhythm regulation systems Overall regulation function Myocardial automatism function Vegetative homeostasis function Stability of regulation function Subcorcial nervous centers activity function

Showing 1: the overall regulation function: 

Showing 1: the overall regulation function The overall regulation function Statistical analysis Heartbeat frequency Mean value

Physiological interpretation of showing 1 (ORF): 

Physiological interpretation of showing 1 (ORF)

Showing 2: the myocardial automatism function: 

Showing 2: the myocardial automatism function Myocardial automatism function Statistical analysis Variation analysis Root-mean-square deviation Variation coefficient Variation amplitude

Showing 3: the vegetative homeostasis function: 

Showing 3: the vegetative homeostasis function Vegetative homeostasis function Variation analysis Variation amplitude Mode amplitude Tension index

Showing 4: stability of regulation: 

Showing 4: stability of regulation Statistical analysis Variation analysis Variation coefficient Correlation analysis Mean value Tension index Correlation coefficient after the first shift Number of shifts before the first negative correlation coefficient Stability of regulation function

Showing 5: SNC activity: 

Showing 5: SNC activity Spectral analysis Subcorcial nervous centers (SNC) activity function The energy of respiratory waves The energy of slow waves The energy of the spectrum in the zero point

RSAS - the integral value: 

RSAS - the integral value The overall regulation function The myocardial automatism function The vegetative homeostasis function Subcorcial nervous centers activity Stability of regulation The regulatory system activity showing

Scale for condition evaluation: 

Scale for condition evaluation

Detailed description of RSAS scale: 

Detailed description of RSAS scale Normal Minimal (or optimal) tension of regulation systems - satisfactory adaptation to environmental factors Functional tension Mobilization of organism protective systems Overwork condition Incapability of adaptation systems to provide optimal reaction to environmental factors Emaciation condition First symptoms of disease may occur

System overview: 

System overview Three tier architecture: 1st tier - RDBMS (MySQL) 2nd tier - Data exchange server 3rd tier - Clients: handheld, administrative, doctor assistant

System architecture diagram: 

System architecture diagram

Exchange server functions: 

Exchange server functions Database access User authorization & access control Messages & diagnostics storage and exchange

Server implementation: 

Server implementation Java ‘daemon’ application Multi - threaded server for parallel client communication & data management Extendable object-based server protocol

Current server implementation : 

Current server implementation Server is now running on: Pentium III 450MHz 64 MB RAM 4GB HDD MySQL serves as a database management system

Server requirements: 

Server requirements Desktop computer Java runtime environment Database access through JDBC Permanent Internet connection

Portable client functions: 

Portable client functions Real-time data collection & filtering Temporal storage for data Real-time evaluations Evaluation results display Visual and sound alarm Regular data uploading to server

Client implementation: 

Client implementation Lightweight Java application Multi - threaded for parallel data collection and real-time processing Establishes only temporary Internet connection for data transfer Pulse sensor as a kernel module

Current client implementation: 

Current client implementation Carrier’s client is working on: AMD K6-2 333MHz 32 MB RAM 8 MB Flash ROM 160 MB PCMCIA hard drive Pulse sensor device attached to a COM port

Client requirements: 

Client requirements ‘Minimal’ hardware requirements Pentium class processor 32 MB RAM 16 MB Flash ROM Minimal Java runtime environment Internet connection (periodically) Some visual & audio capabilities

Add-ons overview: 

Add-ons overview Administrative GUI Doctor assistant Extendable via new clients Extendable via new data evaluation classes

Future... What is to be done?: 

Future... What is to be done? Small handheld or wearable device implementation Develop data filtering methods Extended data analysis methods and classes Embedded Java client platform