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RESEARCH IN AYURVEDA: 

RESEARCH IN AYURVEDA Presented by: Dr. C.D. Siby, B.A.M.S Senior Ayurvedic Physician Ayur Centre Sdn Bhd

Slide2: 

Beginning of Civilization Use of Natural Resources

Differences: 

Differences Ayurvedic Conventional System Synergistic  Active principle Holistic Approach  Reductionist Approach

Active Ingredient Approach compromises:: 

Active Ingredient Approach compromises: Synergetic action Inactive Ingredients Bioflavonoids

Bioflavanoids: 

Bioflavanoids Anti Oxidant Anti Inflammatory Anti Allergic Anti Tumor Anti Allergenic Hepatoprotective

Active Ingredients Approach:: 

Active Ingredients Approach: Side effects Produce free radicals

Free Radicals: 

Free Radicals Oxygen that have lost one electron Terrorist Attack DNA Mutation Disturbs Normal Cell Activities

Free Radicals: 

Free Radicals Hardening of Blood Vessels Stiffness in Tissue ROS (Reactive Oxygen Species) 85% of Chronic and Degenerative Disease (Yulke Niwa)

Diseases linked to Oxy Radicals : 

Diseases linked to Oxy Radicals Cancer  Artheriosclerosis Heart disease Stroke Emphysema  Ulcers Osteoporosis  Cataracts

Diseases linked to Oxy Radicals : 

Diseases linked to Oxy Radicals Sunburns  Diabetes Mellitus Crohn’s Disease Behcet’s Disease Senility  Aging Cerebrovascular Disease Rheumatoid Arthritis

Causes of Free Radicals: 

Causes of Free Radicals Energy Production Pollution Immune System Pollution (Pesticides, Fertilizers)

Drugs: 

Drugs Adriamycin  Bleomycin Mitomycin C  Nitrofurantoin Chloropromazine  Smoking Alcohol  Stress Processed food (Lipid Peroxide) Electro Magnetic Radiation

Free Radical Defenses: 

Free Radical Defenses Anti Oxidant System Enzymes (SOD – Superoxide Dismutase) Nutrients (Vitamin C, Vitamin E, Beta-Carotene, Bioflavanoids, Etc.) Self Repair

Finding the Balance: 

Finding the Balance No need to reduce excess free radicals to zero Strike only proper balance between defense and free radicals

Vitamin (Over Dose): 

Vitamin (Over Dose) Vitamin E to have no effect in reducing death from coronary heart disease when taken in the form of supplementary, in post of menopausal women. But have significant benefits when absorbed from food (Kushi et al, 1996)

Beta Carotene: 

Beta Carotene No effect whatsoever in reducing Malignant Neoplasm’s Cardiovascular disease, or death from all causes (Hennekens et al, 1996)

Beta Carotene: 

Beta Carotene Two recent studies show that beta-carotene and Vitamin E did not prevent lung cancer in male smokers, in fact beta-carotene was linked higher incidence of lung cancer, beta-carotene and Vitamin A were found to increase risk of lung cancer in smokers and workers exposed to asbestos (Omenn et al, 1996)

Enzymes Superoxide Dismutase (SOD): 

Enzymes Superoxide Dismutase (SOD) They are gigantic protein molecules that cannot pass through the walls of the digestive system and into the bloodstream. SOD has only a brief halt-life in the bloodstream.

Enzymes Superoxide Dismutase (SOD): 

Enzymes Superoxide Dismutase (SOD) In less then 5 minutes 50% of it is gone. Broken down by natural body processes Within an hour only 0.1% of it is left.

Artificial Polymer: 

Artificial Polymer Japanese researcher Tatsuya Oda found a way around this – he succeeded in attaching SOD to artificial polymer molecules. Riding on the polymers, the SOD lasts in the bloodstream for around 5 hours But this raises questions about the long term effects of adding an enzyme to the body in large quantities.

How can we keep the balance?: 

How can we keep the balance? In an ideal world, we must find an antioxidant substance with – low molecular weight so they can slip from the digestive tract to the bloodstream undamaged. The anti-freeze radical stability, weight for weight, of an enzyme like SOD The ability to defuse a wide range of free radicals.

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy RASAYANAM (Rejuvenation Combinations) Natural anti-oxidant Weight for weight Stop lipid proxide chain reaction Thousands of times better than antioxidant vitamin and a much researched anti-oxidant

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Food Supplement Increase general immune strength General health General well-being Activate tissue repair mechanism Arresting aging Reversing deterioration therapy

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Plant Chronobiology Optimum time to harvest a herb – is vital since the presence and levels of phytochemicals (such as bioflavanoids) differ at different times of the year.

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Ayurveda herbs were traditional prepared through a long and careful process of grinding in order to reduce each component of a formula to the finest possible powder. Thus, in a complex natural product, many of the important components are tangled together and unassimilable and the grinding process apparently works to enhance their digestibility.

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Ayurveda rasayanam help prevention and regression of breast carcinoma Reduction of aggressive lung cancer metastases Increased survival in skin tumors Prevention of cell transformation Transfromation of cancer cells to normal cells.

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Reduces chemical toxicity and providing protection. Against Cisplatin (potent chemotherapeutic agent but toxin to the kidneys) Detoxifying Adriamycin (which creates free radicals which destroy the DNA of the cancer cells but also damage healthy cells especially in the heart)

Ayurvedic approach to Free Radical Rejuvenation therapy: 

Ayurvedic approach to Free Radical Rejuvenation therapy Protection against toluene (hazardous industrial solvent) Reduces cardiovascular risk factors has anti-aging effects.

Rejuvenation Therapy : 

Rejuvenation Therapy Analysis of one of these Rasayanas revealed a mixture of rich in low molecular weight substances that are well known antioxidants including Vitamin C, Vitamin E, beta carotene, polyphenols, bioflavanoids and riboflavin.

Panchakarma : 

Panchakarma Vasoactive intestinal peptide (VIP), a neuropeptide which dilates the coronary arteries, increased by as much as 80% after a course of panchakarma treatment.

Panchakarma : 

Panchakarma HDL rose by 75% three months after the treatment in subjects whose original values were low. Lipid peroxide levels went up during the treatment but three months after the treatment, were actually lower than what they had been before the treatment. Lowered the stress syndrome and anxiety.

Milk : 

Milk Lowered LDL HDL remained

Vegetarian Recommendation: 

Vegetarian Recommendation Vegetarianism – research has found long term vegetarians to have reduced risk of lipid peroxidation (Krajcovicova-Kudlackova et al, 1995). Vegetarians have a significantly lower incidence of coronary heart disease (slattery et al, 1991). Vegetarianism can actively help reduce coronary heart diseases (Ornish et al, 1990)

Oil Therapy: 

Oil Therapy Sesame oil – cointains 18.4% of sesamol, powerful antioxidant, reduce stress, slow down the aging process, useful in atherosclerosis, arthritis.

Oil Therapy: 

Oil Therapy A number of studies have found significant benefits from massaging new born babies such as enhanced weight gain and responsiveness (Field et al, 1986, rice, 1997). Dr Edward Smith found that those who do abhyanga daily with sesame oil have significantly less bacterial infection on the skin. Sesame Oil is linoleic acid which makes up 40% of the oil.

Oil Therapy: 

Oil Therapy Linoleic acid is know to inhibit the growth of certain bacteria, especially pathogenic bacteria. Linoleic acid is also a powerful anti-inflammatory agent. Finally linoleic acid appears to be an anticarcinogen; inhibit in vitro malignant melanoma growth, colon adenocarcinoma cell line growth (Salerno and Smith, 1991)

Daily Lifestyle: 

Daily Lifestyle People who sleep before 10p.m. will have better digestion and sound sleep as compared to people who sleep after 10 p.m. Stronger chances of ulcers to occur in night shift workers as compared to day shift workers.

Daily Lifestyle: 

Daily Lifestyle “Early to rise” this is also confirmed by a study of the hormone cortisol which regulates the body’s metabolism and is the primary biochemical means of resisting stress (Minors & Waterhouse 1981)

Conclusion: 

Conclusion The ancient herbal formulations are completely different from modern drugs. They are compilations of intact plants or parts of plants, and comprise a profusion of components, a rich stew of molecules intended to enrich the human physiology in its entirety. There is no attempt to isolate the individual molecules.

Conclusion: 

Conclusion Moreover, these formulations are not drugs, but rich herbal foods that are used as supplements to the everyday diet and said to produce overall health and well being.

Conclusion: 

Conclusion Ayurveda asserts that the effectiveness of these herbal formulations comes precisely from the richness of their mixtures. They are a deliberate attempt to maximize synergism; the components help each other to move through the digestive system, arrive at the correct cells, penetrate the cell membranes and achieve intercellular effects.

Conclusion: 

Conclusion Science and Synergism Synergistic effects that enhance effectiveness and reduce side effects. Harmonious direction

Conclusion: 

Conclusion 6000 years ago Creating perfect self Natural beauty Long life More than 600 scientific studies in 27 countries at 200 institutions.

Conclusion: 

Conclusion In Ayurveda the treatment: Assist the nature Support the natural process They do not irritate nor do thy substitute or supress what the body can do itself Ayurveda is a way of life A way of co-operating with the nature

Conclusion: 

Conclusion In Ayurveda the treatment: Living in harmony with her Balances and rejuvenates Reducing its susceptibility Empowering immunity Prevent new disease

THANK YOU: 

THANK YOU

Slide49: 

In the name of Ayurveda: Ayur Centre Sdn Bhd 10 Jalan Dato’ Abu Bakar Seksyen 16 Petaling Jaya Tel : 03-7954 2899 Ayur Centre Sdn Bhd 8, Tambun Heights 31400 Ipoh, Perak Tel : 05-547 3299