Ominiya

Doctors For Life International: An NGO’s perspective on Malaria in Southern AfricaBola Omoniyi, Ph.D.: 

Doctors For Life International: An NGO’s perspective on Malaria in Southern Africa Bola Omoniyi, Ph.D. http: www.doctorsforlifeinternational.com

Doctors For Life (DFL) International: 

Doctors For Life (DFL) International Who we are NGO, NPO Founded in 1991 Over 1300 Medical professionals 75% Africa based HQ: South Africa Operations in SADC countries What we do Malaria R & D (Artemisia) Access to Medicines Care of Orphans & Vulnerable Children Home Based (AIDS) Care Life Skills Education WorkPlace AIDS Programs Care of Abused Women

Caring for Orphans and Vulnerable Children: 

Caring for Orphans and Vulnerable Children

Reaching People With No Access to Medical Care: 

Reaching People With No Access to Medical Care

Taking Medical Care to AIDS Patients at Home: 

Taking Medical Care to AIDS Patients at Home

Education: 

Education Life Skills Based HIV/AIDS Prevention

Developing Artemisia for Treatment of Malaria in Poor and Rural Communities: 

Developing Artemisia for Treatment of Malaria in Poor and Rural Communities

Malaria – Southern Africa: 

Malaria – Southern Africa South Africa: Decreasing incidence of malaria Mozambique: Primary cause of ill health. 40% of outpatients, 60% of pediatric patients One third of all hospital deaths More than 90% of children infected in most areas Significant contributor to high infant & under- 5 mortality 15-30% deaths in pregnant women. Poor rural communities with little medical access most affected. Angola: Number one killer

Malaria Map – Southern Africa: 

Malaria Map – Southern Africa Department of Health RSA

Plasmodium Falciparum: 

Plasmodium Falciparum Majority of cases in South Africa Most South Africans are non-immune Low altitude areas of NE S. Africa P. vivax and P.ovale are rare Seasonal Transmission: Oct - May

Available Anti-Malarials: 

Available Anti-Malarials Quinine Artemisinin derivatives Mefloquine Tetracyclines Clindamycin Chloroquine Halofantrine

Choice of Treatment: 

Choice of Treatment Severity of malaria Resistance pattern Parasite species Patient characteristic – age, pregnancy Geography; Kwazulu-Natal, Limpopo, Mpumalanga

Products under Development: 

Products under Development Doctors For Life International (DFL): Artemisia South African Traditional Medicines Group (SATMERG): Screening of Plant extracts. 25/500 plants with anti-malarial activity identified. National Bioproducts Institute (BPI): Rapid malaria diagnostic kit ( designed for use in rural areas) Ongoing Research: South African Malaria Initiative (SAMI): drug discovery, diagnostics and epidemiology National Institute of Communicable Diseases (NICD): Insecticide resistance University of Cape Town (UCT): Mechanism of chloroquine resistance reversal

Doctors For Life: Malarlife: 

Doctors For Life: Malarlife Artemisia based product Capsules Under preclinical and clinical development Pilot study in the DRC

Mozambique: Improving Malaria Prevention in Rural Areas: 

Mozambique: Improving Malaria Prevention in Rural Areas

Mozambique: Decreasing Malaria Related Mortality in Children: 

Mozambique: Decreasing Malaria Related Mortality in Children

Mozambique: Health Education and Access to Medicines: 

Mozambique: Health Education and Access to Medicines

Angola – Reaching People in War Ravaged Areas: 

Angola – Reaching People in War Ravaged Areas

Angola – Tackling Malaria in RuralAreas: 

Angola – Tackling Malaria in Rural Areas

Doctors For Life: Future Goals: 

Doctors For Life: Future Goals Development of effective and affordable artemisia-based treatment for Malaria Combining artemisia with other effective and affordable products to tackle recrudescence Establish a permanent presence in Mozambique and Angola Expand care of orphans and vulnerable children Expand HIV prevention programs Increase effective collaboration with other organizations and international agencies working on Malaria & HIV/AIDS