EppWestNileVirusADED

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West Nile Virus: in SK Horses 2003 Tasha Epp, DVM MSc graduate student, Epidemiology WCVM: 

West Nile Virus: in SK Horses 2003 Tasha Epp, DVM MSc graduate student, Epidemiology WCVM

WNV Clinical Cases: 

WNV Clinical Cases Passive system of case identification ‘Clinical case‘ = neurologic symptoms and positive IgM ELISA Telephone interview of owner

Case Information: 

Case Information 64% were < 10 yrs 82% were ‘light’ horses 55% were males 72% were dark colored 83% were pleasure horses 68% had no shelter 7% were vaccinated 96% had no travel history

Clinical Picture in SK: 

Clinical Picture in SK

Multi-level model: 

Multi-level model 2-level hierarchy: Horse (130) within RHA (10) Outcome of interest: Health status Significant variables: Color Gender Week of Onset

Interpretation of IgG results: 

Interpretation of IgG results Impact of vaccination on ELISA results Kinetics of positive IgG result once infected Identify a cut-point for the ELISA test

Vaccination study: 

Vaccination study Vaccination dates: Nov 20 and Dec 10 Cut-point = 0.300

Kinetics study: 

Kinetics study

WNV Sero-Prevalence: 

WNV Sero-Prevalence 20 herds Sampled 10 horses August and October IgG and IgM ELISA

IgG results: 

IgG results created 5 regions with 4 herds in each Originally results reported as Pos or Neg/Susp 79% were vacc

Thanks: 

Thanks WCVM Equine Health Research Fund WCVM Interprovincial Graduate Student Fellowship Fund Saskatchewan Health Saskatoon Health Region Saskatchewan Agriculture Canadian Co-operative Wildlife Health Center Wyeth Animal Health